XB-ART-29535Nature October 25, 1984; 311 (5988): 716-21.
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Cell type-specific activation of actin genes in the early amphibian embryo.
Muscle actin genes are the earliest yet described to show cell type-specific activation in amphibian embryos. Gene-specific probes show that alpha-skeletal and alpha-cardiac actin genes start to be transcribed simultaneously at the end of gastrulation, but only in those regions of the mesoderm that subsequently form embryonic muscle. Their expression provides a molecular marker for early cell determination.
PubMed ID: 6548550
Species referenced: Xenopus
Genes referenced: acta4 actc1 actl6a