Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Dev Neurobiol April 1, 2012; 72 (4): 585-99.
Show Gene links Show Anatomy links

Imaging adhesion and signaling dynamics in Xenopus laevis growth cones.

Santiago-Medina M , Myers JP , Gomez TM .

Xenopus laevis provides a robust model system to study cellular signaling and downstream processes during development both in vitro and in vivo. Intracellular signals must function within highly restricted spatial and temporal domains to activate specific downstream targets and cellular processes. Combining the versatility of developing Xenopus neurons with advances in fluorescent protein biosensors and imaging technologies has allowed many dynamic cellular processes to be visualized. This review will focus on the techniques we use to visualize and measure cell signaling, motility and adhesion by quantitative fluorescence microscopy in vitro and in vivo.

PubMed ID: 21465668
PMC ID: PMC3158960
Article link: Dev Neurobiol
Grant support: [+]

Species referenced: Xenopus laevis

Article Images: [+] show captions
References [+] :
Andersen, Live imaging of cell motility and actin cytoskeleton of individual neurons and neural crest cells in zebrafish embryos. 2010, Pubmed