Rusten TE , Vaccari T , Stenmark H .

Audhya, MVB-12, a fourth subunit of metazoan ESCRT-I, functions in receptor downregulation. 2007, Pubmed

Audhya, MVB-12, a fourth subunit of metazoan ESCRT-I, functions in receptor downregulation. 2007, Pubmed
Auth, The TSG101 protein binds to connexins and is involved in connexin degradation. 2009, Pubmed
Babst, Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body. 2002, Pubmed
Babst, The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function. 1998, Pubmed
Babst, Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking. 2000, Pubmed
Babst, Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting. 2002, Pubmed
Bache, STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes. 2003, Pubmed
Bache, The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor. 2006, Pubmed
Bache, The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation. 2004, Pubmed
Bache, Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes. 2003, Pubmed
Bastos, Plk1 negatively regulates Cep55 recruitment to the midbody to ensure orderly abscission. 2010, Pubmed
Berg, Isolation and characterization of rat liver amphisomes. Evidence for fusion of autophagosomes with both early and late endosomes. 1998, Pubmed
Bishop, TSG101/mammalian VPS23 and mammalian VPS28 interact directly and are recruited to VPS4-induced endosomes. 2001, Pubmed
Bishop, ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking. 2000, Pubmed
Buchanan, Proteolytic processing of protocadherin proteins requires endocytosis. 2010, Pubmed
Carlton, Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery. 2007, Pubmed
Chanut-Delalande, The Hrs/Stam complex acts as a positive and negative regulator of RTK signaling during Drosophila development. 2010, Pubmed
Denton, Autophagy, not apoptosis, is essential for midgut cell death in Drosophila. 2009, Pubmed
Doyotte, Depletion of TSG101 forms a mammalian "Class E" compartment: a multicisternal early endosome with multiple sorting defects. 2005, Pubmed
Elia, Dynamics of endosomal sorting complex required for transport (ESCRT) machinery during cytokinesis and its role in abscission. 2011, Pubmed
Fabbro, Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis. 2005, Pubmed
Filimonenko, Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease. 2007, Pubmed
Gibbings, Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity. 2009, Pubmed
Gilbert, Functional interactions between the erupted/tsg101 growth suppressor gene and the DaPKC and rbf1 genes in Drosophila imaginal disc tumors. 2009, Pubmed
Guizetti, Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments. 2011, Pubmed
Herz, vps25 mosaics display non-autonomous cell survival and overgrowth, and autonomous apoptosis. 2006, Pubmed
Huang, Endocytic pathway is required for Drosophila Toll innate immune signaling. 2010, Pubmed
Hurley, Membrane budding and scission by the ESCRT machinery: it's all in the neck. 2010, Pubmed
Hurley, The ESCRT complexes: structure and mechanism of a membrane-trafficking network. 2006, Pubmed
Irion, bicoid RNA localization requires specific binding of an endosomal sorting complex. 2007, Pubmed , Xenbase
Jékely, Hrs mediates downregulation of multiple signalling receptors in Drosophila. 2003, Pubmed
Kantamneni, GISP binding to TSG101 increases GABA receptor stability by down-regulating ESCRT-mediated lysosomal degradation. 2008, Pubmed
Katzmann, Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. 2001, Pubmed
Komada, Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis. 1999, Pubmed
Komander, Breaking the chains: structure and function of the deubiquitinases. 2009, Pubmed
Langelier, Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release. 2006, Pubmed
Lee, Silencing by small RNAs is linked to endosomal trafficking. 2009, Pubmed
Lee, ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration. 2007, Pubmed
Lee, Inhibition of autophagy induction delays neuronal cell loss caused by dysfunctional ESCRT-III in frontotemporal dementia. 2009, Pubmed
Leithe, Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101. 2009, Pubmed
Leung, Evolution of the multivesicular body ESCRT machinery; retention across the eukaryotic lineage. 2008, Pubmed
Lindås, A unique cell division machinery in the Archaea. 2008, Pubmed
Lloyd, Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila. 2002, Pubmed
Lobert, Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes. 2010, Pubmed
Lobert, The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain. 2012, Pubmed
Lu, TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation. 2003, Pubmed
Malerød, Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation. 2007, Pubmed
Martin-Serrano, Host factors involved in retroviral budding and release. 2011, Pubmed
Michelet, The ESCRT-III protein CeVPS-32 is enriched in domains distinct from CeVPS-27 and CeVPS-23 at the endosomal membrane of epithelial cells. 2009, Pubmed
Mizushima, Autophagy fights disease through cellular self-digestion. 2008, Pubmed
Moberg, Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth. 2005, Pubmed
Morita, Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance. 2010, Pubmed
Morita, Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis. 2007, Pubmed
Mukai, Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt. 2010, Pubmed
Nezis, Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis. 2010, Pubmed
Piddini, Arrow (LRP6) and Frizzled2 cooperate to degrade Wingless in Drosophila imaginal discs. 2005, Pubmed
Pérez-Sala, The C-terminal sequence of RhoB directs protein degradation through an endo-lysosomal pathway. 2009, Pubmed
Raiborg, The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins. 2009, Pubmed
Raiborg, FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes. 2001, Pubmed
Rodahl, Disruption of Vps4 and JNK function in Drosophila causes tumour growth. 2009, Pubmed
Roudier, CeVPS-27 is an endosomal protein required for the molting and the endocytic trafficking of the low-density lipoprotein receptor-related protein 1 in Caenorhabditis elegans. 2005, Pubmed
Ruland, p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101. 2001, Pubmed
Rusten, ESCRTs and Fab1 regulate distinct steps of autophagy. 2007, Pubmed
Rusten, How do ESCRT proteins control autophagy? 2009, Pubmed
Sagona, PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody. 2010, Pubmed
Sahu, Microautophagy of cytosolic proteins by late endosomes. 2011, Pubmed
Saksena, ESCRTing proteins in the endocytic pathway. 2007, Pubmed
Samson, Molecular and structural basis of ESCRT-III recruitment to membranes during archaeal cell division. 2011, Pubmed
Samson, A role for the ESCRT system in cell division in archaea. 2008, Pubmed
Seto, Internalization is required for proper Wingless signaling in Drosophila melanogaster. 2006, Pubmed
Sevrioukov, A mutation in dVps28 reveals a link between a subunit of the endosomal sorting complex required for transport-I complex and the actin cytoskeleton in Drosophila. 2005, Pubmed
Shim, CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis. 2006, Pubmed
Slagsvold, Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain. 2005, Pubmed
Spitzer, The Arabidopsis elch mutant reveals functions of an ESCRT component in cytokinesis. 2006, Pubmed
Taelman, Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes. 2010, Pubmed , Xenbase
Teo, ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes. 2006, Pubmed
Thompson, Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila. 2005, Pubmed
Tsunematsu, Distinct functions of human MVB12A and MVB12B in the ESCRT-I dependent on their posttranslational modifications. 2010, Pubmed
Tu, Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions. 2010, Pubmed
Urwin, Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations. 2010, Pubmed
Vaccari, Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants. 2009, Pubmed
Vaccari, The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking. 2005, Pubmed
Vardhana, Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster. 2010, Pubmed
Vicente-Manzanares, Non-muscle myosin II takes centre stage in cell adhesion and migration. 2009, Pubmed
Williams, The emerging shape of the ESCRT machinery. 2007, Pubmed
Wollert, Membrane scission by the ESCRT-III complex. 2009, Pubmed
Wollert, Molecular mechanism of multivesicular body biogenesis by ESCRT complexes. 2010, Pubmed
Yamada, Signal-transducing adaptor molecules STAM1 and STAM2 are required for T-cell development and survival. 2002, Pubmed
Yamada, Loss of hippocampal CA3 pyramidal neurons in mice lacking STAM1. 2001, Pubmed
Yorikawa, Human CHMP6, a myristoylated ESCRT-III protein, interacts directly with an ESCRT-II component EAP20 and regulates endosomal cargo sorting. 2005, Pubmed