Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Methods Mol Biol January 1, 2013; 935 113-25.
Show Gene links Show Anatomy links

Generation of transgenic X. laevis models of retinal degeneration.

Tam BM , Lai CC , Zong Z , Moritz OL .

Transgenic models are invaluable tools for researching retinal degenerative disease mechanisms. However, they are time-consuming and expensive to generate and maintain. We have developed an alternative to transgenic rodent models of retinal degeneration using transgenic Xenopus laevis. We have optimized this system to allow rapid analysis of transgene effects in primary transgenic animals, thereby providing an alternative to establishing transgenic lines, and simultaneously allowing rigorous comparisons between the effects of different transgenes.

PubMed ID: 23150364
Article link: Methods Mol Biol
Grant support: [+]