XB-ART-46962Biochim Biophys Acta August 1, 2012; 1818 (8): 1952-61.
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Connexins in epidermal homeostasis and skin disease.
The expression of multiple connexin (Cx) types in the epidermis, their differential expression during wound closure and the association of skin pathology with specific Cx gene mutations, are indicative of important functions for Cxs in the skin. In this review, we focus on the role of Cx proteins in the epidermis and during wound healing and discuss mutations in Cx genes which cause skin disease. This article is part of a Special Issue entitled: The Communicating junctions, composition, structure and characteristics.
PubMed ID: 21933662
Article link: Biochim Biophys Acta
Species referenced: Xenopus
Genes referenced: gja1 gjb2 gjb3 gjb4
GO keywords: wound healing
Disease Ontology terms: Bart-Pumphrey syndrome
OMIMs: KERATITIS-ICHTHYOSIS-DEAFNESS SYNDROME, AUTOSOMAL DOMINANT; KIDAD