XB-ART-50611Curr Biol August 18, 2014; 24 (16): R746-9.
Multiciliogenesis: multicilin directs transcriptional activation of centriole formation.
During differentiation of multiciliated cells, numerous centrioles are generated in each cell to act as templates for the formation of a corresponding number of cilia. A new study reveals that multicilin, a protein required for multiciliogenesis, is a key component of a regulatory complex that activates the transcription of genes required for centriole formation.
PubMed ID: 25137586
Article link: Curr Biol
Species referenced: Xenopus
Genes referenced: mcidas