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XB-ART-53442
Mol Cell 2007 Jul 20;272:311-323. doi: 10.1016/j.molcel.2007.06.014.
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RETRACTED: Sealing of chromosomal DNA nicks during nucleotide excision repair requires XRCC1 and DNA ligase III alpha in a cell-cycle-specific manner.

Moser J , Kool H , Giakzidis I , Caldecott K , Mullenders LHF , Fousteri MI .


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This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the editors. Molecular Cell has retracted this article following the results of an investigation carried out by Leiden University Medical Center's Committee of Scientific Integrity, which concluded that unacceptable data manipulation by the last author Maria Fousteri led to breaches of scientific integrity, making these results unreliable. Section 2.2, item 2 of the report indicates several duplications in Figure 4 and that, upon inspection of original data, several proteins stained for by western blotting following immunoprecipitation were incorrectly assigned (Figure 4B). The XPA panel in Figure 4A is a mirrored duplication of an image that was published in Figure 5C of Fousteri et al., 2006 (Mol. Cell 23, 471-482, https://doi.org/10.1016/j.molcel.2006.06.029). Additional details can be found in the redacted version of the investigation report (https://www.lumc.nl/cen/att/80813053317221/1263833/report-lumc-committee-scientific-integrity).

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Species referenced: Xenopus
Genes referenced: lig3 xpa xrcc1