Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-7575
Biosci Biotechnol Biochem 2002 Jan 01;661:185-7.
Show Gene links Show Anatomy links

Inhibition of translation and progesterone-induced maturation of Xenopus oocytes by expressing the amino-terminal portion of the eukaryotic translation initiation factor 4G.

Wakiyama M , Miura K .


???displayArticle.abstract???
The eukaryotic translation initiation factor 4G (eIF4G) plays a pivotal role in translation. EIF4G interacts with several other factors including eIF4E, which is a cap-binding protein, and the poly(A)-binding protein (PABP). In this work, we demonstrate that the expression of the amino-terminal one-third of eIF4G, which interacts with eIF4E and PABP, in Xenopus oocyte inhibits translation and progesterone-induced maturation.

???displayArticle.pubmedLink??? 11866104
???displayArticle.link??? Biosci Biotechnol Biochem


Species referenced: Xenopus
Genes referenced: eif4e eif4g1 pabpc1 pabpc4