Pommereit D et al. (2001), Xpitx3: a member of the Rieg/Pitx gene family e...

XB-ART-9256

Mech Dev 2001 Apr 01;1021-2:255-7. doi: 10.1016/s0925-4773(01)00305-7.

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Xpitx3: a member of the Rieg/Pitx gene family expressed during pituitary and lens formation in Xenopus laevis.

Pommereit D , Pieler T , Hollemann T .

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Xpitx3 is the Xenopus homologue of the mouse Pitx3 gene and belongs to the family of RIEG/PITX homeobox genes. Here, we report on the embryonic expression of Xpitx3. It is transcribed in the presumptive pituitary already at the open neural tube stage. During further development Xpitx3 is strongly transcribed in the pituitary Anlage, the lens placodes and head mesenchyme, respectively.

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Species referenced: Xenopus laevis
Genes referenced: pitx3 rpe

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	Fig. 2. Expression of Xpitx3 during Xenopus development. Whole-mount in situ hybridization was performed using Xpitx3 antisense RNA and staged Xenopus embryos. Nieuwkoop–Faber stages of embryogenesis are indicated. (a,b′,c,d,e,f,f′,g) Lateral view; (b) anterior view of the embryo; to improve resolution cleared embryos in lateral view are shown in (b′,f′,f′). (g′,g′) show frontal sections of the embryo shown in (g). In (f′) the embryo of (f) is shown in an anterior view. ale, anterior lens epithel; fbv, forebrain ventricle; ec, eye cup; fe, foregut endoderm; gl, ganglion layer; hm, head mesenchyme; il, inner layer; inl, inner nuclear layer; lp, lens placode; lpm, lateral plate mesoderm; lv, lens vesicle; nc, notochord; pa, pituitary Anlage; pt, pituitary; rpe, retinal pigment epithel; pfl, primary lens fibres; roa, roof of archenteron.
	pitx3 (paired-like homeodomain 3) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 17, lateral view, anterior left, dorsal up.
	pitx3 (paired-like homeodomain 3)gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 21, anterior view, dorsal up.
	pitx3 (paired-like homeodomain 3) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 21, mid section, lateral view, anterior left, dorsal up.
	pitx3 (paired-like homeodomain 3) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 28, anterior view, dorsal up.
	pitx3 (paired-like homeodomain 3) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 38, anterior view, dorsal up.
	pitx3 (paired-like homeodomain 3) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 38, transverse section through eye/head region, dorsal up.