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XB-ART-9260
Mech Dev 2001 Apr 01;1021-2:227-30. doi: 10.1016/s0925-4773(01)00296-9.
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Cloning and expression of CSAL2, a new member of the spalt gene family in chick.

Farrell ER , Tosh G , Church E , Münsterberg AE .


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In this study we describe cloning and expression of CSAL2, a second member of the spalt gene family in chick. All spalt proteins are characterized by the presence of multiple zinc-finger motifs, which are highly conserved. Mutations in HSAL1, a human spalt gene result in Townes-Brocks syndrome (TBS). We show here that CSAL2 is expressed in many of the tissues affected in TBS, including neural tissue, limb buds, mesonephros and cloaca.

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Species referenced: Xenopus
Genes referenced: sall1