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XB-ANTIBODY-17252034

Antibody Name: Cdk1 Ab2

Common Name: Phospho-cdc2 (Tyr15)

RRID: AB_331460
Synonyms: 9111

Antigens
Gene: cdk1 , cdk5

Clone Type: Polyclonal
Source: Cell Signaling Technology

Antibody
Clone Number
Purification Affinity Purification
Isotype isotype unknown
Host Organism rabbit
Xenopus Reactivity tropicalis, laevis
Non-Xenopus Reactivity
Description: Phospho-cdc2 (Tyr15) Antibody, supplied by Cell Signalliung Technologies Cat #9111. Phospho-cdc2 (Tyr15) Antibody detects endogenous levels of cdc2, CDK2 and CDK5 only when phosphorylated at tyrosine 15. Based on sequence similarity, the antibody may also cross-react with CDK3. The antibody does not cross-react with CDK4, CDK6 or CDK7. It does detect the yeast orthologue of cdc2 (cdc28) when phosphorylated at tyrosine 19. Cite this (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
Immunogen
Name CDK1
Type synthetic sequence
Post Translational Modifications Phosphorylated
Source Organism human
Description Synthetic phosphopeptide corresponding to residues surrounding Tyr15 of human cdk1.
Sequence
Reported Usage
western blot 1:1000
immunoprecipitation 1:50
Publications
First: Thr-161 phosphorylation of monomeric Cdc2. Regulation by protein phosphatase 2C in Xenopus oocytes., J Biol Chem 2002  
Most recent: Bistable, Biphasic Regulation of PP2A-B55 Accounts for the Dynamics of Mitotic Substrate Phosphorylation., Curr Biol 2021                                
View All Papers