Papers
(21)
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R-spondins are BMP receptor antagonists in Xenopus early embryonic development. , Lee H , Lee H , Seidl C, Sun R, Glinka A , Niehrs C ., Nat Commun. November 4, 2020; 11 (1): 5570.
Development: scaling to size by protease inhibition. , De Robertis EM , Colozza G ., Curr Biol. August 5, 2013; 23 (15): R652-4.
Dorsal- ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases. , Ploper D, Lee HX , De Robertis EM ., Dev Biol. April 15, 2011; 352 (2): 317-28.
A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer. , Rankin SA , Rankin SA , Kormish J , Kofron M , Jegga A, Zorn AM ., Dev Biol. March 15, 2011; 351 (2): 297-310.
BMP antagonists and FGF signaling contribute to different domains of the neural plate in Xenopus. , Wills AE , Choi VM, Bennett MJ, Khokha MK , Harland RM ., Dev Biol. January 15, 2010; 337 (2): 335-50.
Enzymatic regulation of pattern: BMP4 binds CUB domains of Tolloids and inhibits proteinase activity. , Lee HX , Mendes FA, Plouhinec JL, De Robertis EM ., Genes Dev. November 1, 2009; 23 (21): 2551-62.
Syndecan-1 regulates BMP signaling and dorso- ventral patterning of the ectoderm during early Xenopus development. , Olivares GH, Carrasco H, Aroca F, Carvallo L, Segovia F, Larraín J ., Dev Biol. May 15, 2009; 329 (2): 338-49.
Differential requirements of BMP and Wnt signalling during gastrulation and neurulation define two steps in neural crest induction. , Steventon B , Araya C, Linker C, Kuriyama S , Mayor R ., Development. March 1, 2009; 136 (5): 771-9.
Crossveinless-2 Is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning. , Ambrosio AL, Taelman VF, Lee HX , Lee HX , Metzinger CA, Coffinier C, De Robertis EM ., Dev Cell. August 1, 2008; 15 (2): 248-60.
Scaling of the BMP activation gradient in Xenopus embryos. , Ben-Zvi D, Shilo BZ, Fainsod A , Barkai N., Nature. June 26, 2008; 453 (7199): 1205-11.
The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm. , Spagnoli FM , Brivanlou AH ., Development. February 1, 2008; 135 (3): 451-61.
The Xenopus Nieuwkoop center and Spemann-Mangold organizer share molecular components and a requirement for maternal Wnt activity. , Vonica A , Gumbiner BM ., Dev Biol. December 1, 2007; 312 (1): 90-102.
The opposing homeobox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning. , Sander V, Reversade B , De Robertis EM ., EMBO J. June 20, 2007; 26 (12): 2955-65.
The secreted EGF-Discoidin factor xDel1 is essential for dorsal development of the Xenopus embryo. , Arakawa A, Matsuo-Takasaki M, Takai A, Inomata H , Matsumura M, Ikeya M, Takahashi K, Miyachi Y, Sasai N, Sasai Y ., Dev Biol. June 1, 2007; 306 (1): 160-9.
Embryonic dorsal- ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases. , Lee HX , Ambrosio AL, Reversade B , De Robertis EM ., Cell. January 13, 2006; 124 (1): 147-59.
Regulation of ADMP and BMP2/4/7 at opposite embryonic poles generates a self-regulating morphogenetic field. , Reversade B , De Robertis EM ., Cell. December 16, 2005; 123 (6): 1147-60.
Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos. , Reversade B , Kuroda H , Lee H , Mays A, De Robertis EM ., Development. August 1, 2005; 132 (15): 3381-92.
Biglycan is a new extracellular component of the Chordin- BMP4 signaling pathway. , Moreno M, Muñoz R, Aroca F, Labarca M, Brandan E, Larraín J ., EMBO J. April 6, 2005; 24 (7): 1397-405.
Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus. , Kuroda H , Wessely O , De Robertis EM ., PLoS Biol. May 1, 2004; 2 (5): E92.
The pro-BMP activity of Twisted gastrulation is independent of BMP binding. , Oelgeschläger M , Reversade B , Larraín J , Little S, Mullins MC, De Robertis EM ., Development. September 1, 2003; 130 (17): 4047-56.
Chordin is required for the Spemann organizer transplantation phenomenon in Xenopus embryos. , Oelgeschläger M , Kuroda H , Reversade B , De Robertis EM ., Dev Cell. February 1, 2003; 4 (2): 219-30.