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XB-MORPHOLINO-17249296
Morpholino Name:
chrd.1 MO2
Synonyms: Chd MO2, Chd-MO, Chd-MO2, Chordin 1, Chordin 2
Target mRNA: chrd.1
Morpholino Type: translation blocking morpholino (ATG)
Sequence: 5' ACAGCATTTTTGTGGTTGTCCCGAA 3'
Source: Gene Tools LLC
Synonyms: Chd MO2, Chd-MO, Chd-MO2, Chordin 1, Chordin 2
Target mRNA: chrd.1
Morpholino Type: translation blocking morpholino (ATG)
Sequence: 5' ACAGCATTTTTGTGGTTGTCCCGAA 3'
Source: Gene Tools LLC
| Target mRNA | tropicalis | laevis.L | laevis.S | ||
| Identities | 21/25 | 23/25 | |||
| genomic MO |
5' CTCGGGGCTACCACAAAAATGCTTT 3' ||||| | |||||||||||||| | 3' AAGCCCTGTTGGTGTTTTTACGACA 5' | 5' TTCAGGACTACCACAAAAATGCTGT 3' ||| |||| |||||||||||||||| 3' AAGCCCTGTTGGTGTTTTTACGACA 5' | |||
Genomic Alignments  |
Position | Identity | Strand | Target | mRNA |
| laevis 9.2 | chr5L:97277967..97277991 | 23/25 | Antisense | target | chrd.1.L |
| chr5L:97331623..97331647 | 25/25 | Antisense | off-target | chrd.2.L | |
| chr2S:65749335..65749359 | 21/25 | Sense | off-target | col8a2.S | |
| Scaffold30:388764..388788 | 21/25 | unknown | |||
| chr5L:69648971..69648995 | 21/25 | unknown | |||
| tropicalis 10.0 | Chr5:99618063..99618087 | 21/25 | Antisense | target | chrd.1 |
| Chr8:41085274..41085298 | 21/25 | unknown | |||
| Publications | |||||
| First: |
Chordin is required for the Spemann organizer transplantation phenomenon in Xenopus embryos., Dev Cell 2003  |
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| Most recent: |
R-spondins are BMP receptor antagonists in Xenopus early embryonic development., Nat Commun 2020  |
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| View All Papers | |||||
