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XB-MORPHOLINO-17250345

Morpholino Name: smn1 MO2
Synonyms: MoSMNatg
Target mRNA: smn1

Morpholino Type: translation blocking morpholino (ATG)
Sequence: 5' GAGCCTGCCATAGACACGCTACTTC 3'

Source: Gene Tools LLC


Target mRNA tropicalis laevis.L laevis.S
Identities 25/25 22/25 22/25
genomic

MO
5' GAAGTAGCGTGTCTATGGCAGGCTC 3' ||||||||||||||||||||||||| 3' CTTCATCGCACAGATACCGTCCGAG 5' 5' AAAGTAGCGTGTCTATGGCAGGTTT 3' ||||||||||||||||||||| | 3' CTTCATCGCACAGATACCGTCCGAG 5' 5' AAAGTAGCGTGTCTATGGCAGGTTT 3' ||||||||||||||||||||| | 3' CTTCATCGCACAGATACCGTCCGAG 5'
Genomic Alignments Position Identity Strand Target Target mRNA
laevis 10.1 Chr1L:198698126..198698150 22/25 Antisense target smn1.L
Chr1S:170693686..170693710 22/25 Antisense target smn1.S
Chr4L:151781802..151781826 21/25 Sense off-target cacna2d3.L
Chr2L:23007915..23007939 21/25 Sense off-target cadm2.L
tropicalis 10.0 Chr1:182582339..182582363 25/25 Antisense target smn1
Chr2:60450393..60450417 21/25 Sense off-target cttnbp2nl
Publications
First: Reduced levels of survival motor neuron protein leads to aberrant motoneuron growth in a Xenopus model of muscular atrophy., Neurogenetics 2010    
Most recent:
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