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Summary Attributions Wiki
XB-MORPHOLINO-19778018
Morpholino Name: ascl1 MO7
Synonyms: Ascl1a spMO, ascl1a splicing MO
Target mRNA: ascl1

Morpholino Type: splice blocking morpholino
Sequence: 5' GATGGAGGCAACTCACCTGCTACTC 3'

Source: Gene Tools LLC


Target mRNA laevis.L laevis.S
Identities 25/25 23/25
genome
MO
 
5' GAGTAGCAGGTGAGTTGCCTCCATC 3'
   |||||||||||||||||||||||||
3' CTCATCGTCCACTCAACGGAGGTAG 5'
 
5' GAGAAGCAGGTCAGTTGCCTCCATC 3'
   ||| ||||||| |||||||||||||
3' CTCATCGTCCACTCAACGGAGGTAG 5'
     
Genomic Alignments Position Identity Strand Target Target mRNA
laevis 10.1 Chr3L:57039979..57040003 25/25 Antisense target ascl1.L
Chr3S:97600255..97600279 23/25 Antisense target ascl1.S
Chr7L:33202844..33202868 22/25 Antisense off-target rpp30.L
Chr6L:61903052..61903076 21/25 Antisense off-target sugct.L
Chr1S:142893711..142893735 21/25 Sense off-target LOC108707130
tropicalis 10.0 Chr6:120019532..120019556 21/25 Antisense off-target slco5a1
Publications
???morpholino.displaySummary.papersFirst??? A novel role for Ascl1 in the regulation of mesendoderm formation via HDAC-dependent antagonism of VegT., Development 2016                              
???morpholino.displaySummary.papersRecent??? KDM3A-mediated demethylation of histone H3 lysine 9 facilitates the chromatin binding of Neurog2 during neurogenesis., Development 2017                            
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