|
Xtr.wwoxemHorb
|
X.tropicalis |
wwox
|
CRISPR knockout of wwox (WW domain containing oxidoreductase), a gene associated with esophageal can... |
NXR
|
Xtr.vwa2emNXR
|
X.tropicalis |
vwa2
|
CRISPR knock out of vwa2 (von Willebrand factor A domain containing 2 ). Germ line transmission conf... |
NXR
|
Xtr.tupmZimml
|
X.tropicalis |
unknown
|
Mutation affecting axial development identified in the Mill Hill screen of ENU-induced mutations. |
EXRC
|
Xtr.tp53em_del2/+_Vlemx
|
X.tropicalis |
tp53
|
Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deletio... |
|
Xtr.tp53em_del1/em_del2_Vlemx
|
X.tropicalis |
tp53
|
Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del... |
|
Xtr.tp53em_del1/+_Vlemx
|
X.tropicalis |
tp53
|
Deletion is expected to give rise to nonsense-mediated
decay since due to the frame-shifting deleti... |
|
Xtr.thratmShiyb
|
X.tropicalis |
|
This line was created using TALENS targeting exon 4 (the third coding exon) of the X. tropicalis thr... |
|
Xtr.tbxtemJcsm
|
X.tropicalis |
tbxt
|
Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ... |
EXRC
|
Xtr.tbxt.2em2Jcsm
|
X.tropicalis |
tbxt.2
|
Talen-induced mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... |
EXRC
|
Xtr.tbxt.2em1Jcsm
|
X.tropicalis |
tbxt.2
|
Talen-mediated mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... |
EXRC
|
Xtr.tbxt,tbxt.2emJcsm
|
X.tropicalis |
tbxt
|
Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in... |
EXRC
|
Xtr.srd5a2emNXR
|
X.tropicalis |
srd5a2
|
CRISPR knockout of srd5a2 (steroid 5 alpha-reductase 2), Confirmed germ line transmission. animals c... |
NXR
|
Xtr.sox3emHorb
|
X.tropicalis |
sox3
|
CRISPR knockout of sox3 (SRY-box 3), Current mosaic founders, Not tested for germline transmission. ... |
NXR
|
Xtr.snai1emNXR
|
X.tropicalis |
snai1
|
CRISPR knockout of snai1 (snail family zinc finger 1) in X. tropicalis. germline transmission confir... |
NXR
|
Xtr.smad4.1mZimml
|
X.tropicalis |
smad4
|
Mutation affecting haematopoiesis identified in a screen for ENU-induced mutations at Mill Hill. Pos... |
EXRC
|
Xtr.six1em2NXR
|
X.tropicalis |
six1
|
CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc... |
|
Xtr.six1em1NXR
|
X.tropicalis |
six1
|
CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc... |
NXR
|
Xtr.rflciiemNXR
|
X.tropicalis |
rflcii
|
CRISPR KO of rflcii ( relaxin family locus C type II ) in X tropicalis. Germ line transmission not y... |
NXR
|
Xtr.raxmGrngr
|
X.tropicalis |
rax
|
This mutant line was generated in an ENU screen from the Grainger lab by TILLING (Targeting Induced ... |
NXR
|
Xtr.pou3f4emHorb
|
X.tropicalis |
pou3f4
|
CRISPR knockout of pou3f4 (POU class 3 homeobox 4). Current mosaic founders, not tested for germline... |
NXR
|
Xtr.olig4emHorb
|
X.tropicalis |
olig4
|
CRISPR knockout of olig4 (oligodendrocyte transcription factor 4). Current mosaic founders, not test... |
NXR
|
Xtr.nr2f2emNXR
|
X.tropicalis |
nr2f2
|
CRISPR knockout fo nr2f2 (nuclear receptor subfamily 2 group F member 2 ). Germ line transmission co... |
NXR
|
Xtr.npntinsZimml
|
X.tropicalis |
npnt
|
Nephronectin insertional mutation (probably null). Insertion of Tg(nkx2.5:GFP) transgene between 3rd... |
EXRC
|
Xtr.myf6emNXR
|
X.tropicalis |
myf6
|
TALENS knockout of myf6 (myogenic factor 6) in X tropicalis. Germ line transmission not yet confirme... |
NXR
|
Xtr.legmZimml
|
X.tropicalis |
unknown
|
Mutation affecting otoconia formation identified in the Mill Hill screen of ENU-induced mutations. |
EXRC
|
Xtr.kiff11emHorb
|
X.tropicalis |
kif11
|
CRISPR knockout of kif11 (kinesin family member 11). Germ line transmission not yet confirmed. F0 fo... |
NXR
|
Xtr.gfi1em2Horb
|
X.tropicalis |
gfi1
|
CRISPR knockout of gfi1 (growth factor independent 1 transcription repressor). Germ line transmissio... |
NXR
|
Xtr.gfi1em1Horb
|
X.tropicalis |
gfi1
|
CRISPR knockout of gfi1 (growth factor independent 1 transcription repressor). Germ line transmissio... |
NXR
|
Xtr.frzb,frzb2emHorb
|
X.tropicalis |
frzb2
|
double CRISPR knockout of frzb (frizzled related protein ) and frzb2 (frizzled related protein 2). C... |
NXR
|
Xtr.fibinemHorb
|
X.tropicalis |
fibin
|
CRISPR knockout of fibin (fin bud initiation factor homolog), Confirmed germline transmission. Custo... |
NXR
|
Xtr.ezh2emHorb
|
X.tropicalis |
ezh2
|
CRISPR knockout of ezh2 (enhancer of zeste 2 polycomb repressive complex 2 subunit), Germ line trans... |
NXR
|
Xtr.eya1em1NXR
|
X.tropicalis |
eya1
|
CRISPR knockout of eya1 (EYA transcriptional coactivator and phosphatase 1). Germline transmission ... |
NXR
|
Xtr.dtlemHorb
|
X.tropicalis |
dtl
|
CRISPR knockout of dtl (denticleless E3 ubiquitin protein ligase homolog), Current mosaic founders, ... |
NXR
|
Xtr.dstmZimml
|
X.tropicalis |
unknown
|
Mutation affecting the haematopoietic system identified in the Mill Hill screen for ENU-induced muta... |
EXRC
|
Xtr.csnk1g2emNXR
|
X.tropicalis |
csnk1g2
|
CRISPR knockout of csnk1g2 (casein kinase 1 gamma 2). Germ line transmission confirmed. Mutation is ... |
NXR
|
Xtr.cacna1hem1NXR
|
X.tropicalis |
cacna1h
|
CRISPR knockout of cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit). Mutation ... |
NXR
|
Xtr.amhem3NXR
|
X.tropicalis |
amh
|
CRISPR knockout of amh (anti-Mullerian hormone ). Confirmed germline transmission. Custom mutant gen... |
NXR
|
Xtr.amhem1NXR
|
X.tropicalis |
amh
|
CRISPR knockout of amh (anti-Mullerian hormone). Germline transmission confirmed. +8bp mutation in a... |
NXR
|
Xtr.amhr2emNXR
|
X.tropicalis |
amhr2
|
CRISPR knockout of amhr2 (anti-Mullerian hormone receptor type II ). Confirmed germline transmission... |
NXR
|
Xtr.aif1lem1Horb
|
X.tropicalis |
aif1l
|
CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Confirmed germline transmission. Cu... |
NXR
|
Xtr.ahrem1NXR
|
X.tropicalis |
ahr
|
TALEN generated mutant line, made by the NXR. Germ line transmission confirmed. ,+2bp mutation: CCAT... |
NXR
|
Xla.xdm-wemNXR
|
X.laevis |
xdm-w.L
|
CRISPR knock out of xdm-w (doublesex and mab3 related transcription factor W ). Germ Line transmissi... |
NXR
|
Xla.thrbem1NXR
|
X.laevis |
thrb.L
|
CRISPR knockout of thrb.L thyroid hormone receptor, beta L homolog). germline transmission confirmed... |
NXR
|
Xla.sox10emHorb
|
X.laevis |
sox10.L
|
CRISPR knockout of sox10 (SRY-box 10). Confirmed germline transmission in sox10.L (waiting for confi... |
NXR
|
Xla.slc45a2em2NXR
|
X.laevis |
slc45a2.L
|
CRISPR knockout of slc45a2 (solute carrier family 45 member 2 ). Screened for germline transmission.... |
NXR
|
Xla.pkhd1emHorb
|
X.laevis |
pkhd1.L
|
CRISPR knockout of pkhd1 (PKHD1, fibrocystin/polyductin), Germ line transmission confirmed. Animals ... |
NXR
|
Xla.pkd2emHorb
|
X.laevis |
pkd2.L
|
CRISPR knockout of pkd2 (polycystin 2, transient receptor potential cation channel ). Confirmed germ... |
NXR
|
Xla.pcntemHorb
|
X.laevis |
pcnt.L
|
CRISPR knockout of pcnt (pericentrin ). Confirmed germline transmission. Custom mutant generated by ... |
NXR
|
Xla.olig2emHorb
|
X.laevis |
olig2.L
|
CRISPR knockout of olig2 (oligodendrocyte lineage transcription factor 2) in X. laevis. KOs both oli... |
NXR
|
Xla.npffr1.1emEXRC
|
X.laevis |
npffr1.1.L
|
Crispr-Cas9 mutation in the npffr1.1 gene (neuropeptide FF receptor 1, gene 1 ). |
EXRC
|
