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Xtr.zmym4emNXR
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X. tropicalis |
zmym4
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CRISPR KO of zmym4 (zinc finger MYM-type containing 4) in X. tropicalis. Currently mosaic founds F0 ... |
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Xtr.zeb2emNXR
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X. tropicalis |
zeb2
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CRISPR KO of zeb2 (zinc finger E-box binding homeobox 2), a gene associated with Mowat-Wilson syndro... |
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Xtr.zbtb21emHorb
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X. tropicalis |
zbtb21
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CRISPR knockout of zbtb21(zinc finger and BTB domain containing 21), Current mosaic founders, Not te... |
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Xtr.zbtb14emHorb
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X. tropicalis |
zbtb14
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CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Germ line transmission confirm... |
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Xtr.ywhazemNXR
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X. tropicalis |
ywhaz
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CRISPR KO of ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). ge... |
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Xtr.xbp1emNXR
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X. tropicalis |
xbp1
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CRISPR KO of xbp1 ( X-box binding protein 1 ) a gene assocaited with Major Affected Disorder in huma... |
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Xtr.wwoxemHorb
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X. tropicalis |
wwox
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CRISPR knockout of wwox (WW domain containing oxidoreductase), a gene associated with esophageal can... |
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Xtr.wt1emHorb
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X. tropicalis |
wt1
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CRISPR knockout of wt1 (Wilms tumor 1). Germ line transmission confirmed. Animals carry a 5bp deleti... |
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Xtr.wnt11bemNXR
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X. tropicalis |
wnt11b
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CRISPR knockout of wnt11b (wingless-type MMTV integration site family, member 11B ), Germ line tran... |
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Xtr.wbp11emNXR
|
X. tropicalis |
wbp11
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CRISPR knockout of wbp11 (WW domain binding protein 11). Germline transmission confirmed, F2s growin... |
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Xtr.vwa2emNXR
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X. tropicalis |
vwa2
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CRISPR knock out of vwa2 (von Willebrand factor A domain containing 2 ). Germ line transmission conf... |
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Xtr.vangl2emNXR
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X. tropicalis |
vangl2
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CRISPR knockout of vangl2 (VANGL planar cell polarity protein 2 ), a gene associated with neural tub... |
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Xtr.unc45bmZimml
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X. tropicalis |
unc45b
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Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. |
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Xtr.tyremNXR
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X. tropicalis |
tyr
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CRISPR knockout of tyr (tyrosinase), Confirmed germline transmission. Animal carry a 241bp insertion... |
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Xtr.tupmZimml
|
X. tropicalis |
unknown
|
Mutation affecting axial development identified in the Mill Hill screen of ENU-induced mutations. |
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Xtr.tspan8em3Horb
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X. tropicalis |
tspan8
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CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 3rd of 3 tspan lines at... |
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Xtr.tspan8em2Horb
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X. tropicalis |
tspan8
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CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 2nd of 3 tspan lines at... |
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Xtr.tspan8em1Horb
|
X. tropicalis |
tspan8
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CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 1of 3 tspan lines at th... |
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Xtr.tp53em_del2/+_Vlemx
|
X. tropicalis |
tp53
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Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deletio... |
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Xtr.tp53em_del1/em_del2_Vlemx
|
X. tropicalis |
tp53
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Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del... |
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Xtr.tp53em_del1/+_Vlemx
|
X. tropicalis |
tp53
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Deletion is expected to give rise to nonsense-mediated
decay since due to the frame-shifting deleti... |
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Xtr.tlx3em2Horb
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X. tropicalis |
tlx3
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CRISPR mutant line targeting tlx3 (T cell leukemia homeobox 3). Germ lIne transmission was confirmed... |
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Xtr.tlx3em1Horb
|
X. tropicalis |
tlx3
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CRISPR knockout of tlx3 (T cell leukemia homeobox 3). Confirmed germline transmission. Custom mutant... |
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Xtr.thratmShiyb
|
X. tropicalis |
thra
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This line was created using TALENS targeting exon 4 (the third coding exon) of the X. tropicalis thr... |
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Xtr.Tg(mlc2:dnfosl1-eGFP)Qi
|
X. tropicalis |
fosl1
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Fosl1 protein was mutated and truncated to generate 3 mutant polypeptides which then cloned into pc... |
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Xtr.tdrd1emNXR
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X. tropicalis |
tdrd1
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CRISPR knockout of tdrd1 (tudor domain containing 1). Germline transmission not yet confirmed. growi... |
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Xtr.tbxtemJcsm
|
X. tropicalis |
tbxt
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Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ... |
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Xtr.tbxt.2em2Jcsm
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X. tropicalis |
tbxt.2
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Talen-induced mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... |
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Xtr.tbxt.2em1Jcsm
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X. tropicalis |
tbxt.2
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Talen-mediated mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... |
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Xtr.tbxt,tbxt.2emJcsm
|
X. tropicalis |
tbxt
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Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in... |
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Xtr.tbx5emHorb
|
X. tropicalis |
tbx5
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CRISPR knockout of tbx5 (T-box 5 ), Confirmed germline transmission. Custom mutant generated by Horb... |
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Xtr.tbx2emHorb
|
X. tropicalis |
tbx2
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CRISPR knockout of tbx2 (T-box 2), Current mosaic founders, Not tested for germline transmission. |
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Xtr.supt5hmZimml
|
X. tropicalis |
supt5h
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Mutation affecting eye development and melanophore migration identified in the Mill Hill screen for ... |
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Xtr.srd5a3emNXR
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X. tropicalis |
srd5a3
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CRISPR knockout of srd5a3 (steroid 5 alpha-reductase 3), Germ line transmission not yet confirmed. C... |
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Xtr.srd5a2emNXR
|
X. tropicalis |
srd5a2
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CRISPR knockout of srd5a2 (steroid 5 alpha-reductase 2), Confirmed germ line transmission. animals c... |
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Xtr.sox3emHorb
|
X. tropicalis |
sox3
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CRISPR knockout of sox3 (SRY-box 3), Current mosaic founders, Not tested for germline transmission. ... |
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Xtr.sox2emHorb
|
X. tropicalis |
sox2
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CRISPR knockout of sox2 (SRY-box 2). Germ line transmission confirmed. Animals carry a 1bp insertion... |
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Xtr.snai2emNXR
|
X. tropicalis |
snai2
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CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi... |
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Xtr.snai1emNXR
|
X. tropicalis |
snai1
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CRISPR knockout of snai1 (snail family zinc finger 1) in X. tropicalis. germline transmission confir... |
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Xtr.smad4mZimml
|
X. tropicalis |
smad4
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Mutation affecting haematopoiesis identified in a screen for ENU-induced mutations at Mill Hill. Pos... |
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Xtr.six1em2NXR
|
X. tropicalis |
six1
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CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc... |
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Xtr.six1em1NXR
|
X. tropicalis |
six1
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CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc... |
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Xtr.shroom3emHorb
|
X. tropicalis |
shroom3
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CRISPR knockout of shroom3 (shroom family member 3), Current mosaic founders, Germ line transmissio... |
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Xtr.sf3b4emNXR
|
X. tropicalis |
sf3b4
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CRISPR knockout of sf3b4 (splicing factor 3b subunit 4) in X tropicalis. sf3b4 is a gene associated ... |
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Xtr.rxrgemHorb
|
X. tropicalis |
rxrg
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Description: CRISPR knockout of rxrg (retinoid X receptor gamma). Confirmed germline transmission. C... |
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Xtr.rxrbemHorb
|
X. tropicalis |
rxrb
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CRISPR knockout of rxrb (retinoid X receptor beta). Confirmed germline transmission. Animals carry a... |
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Xtr.rxraemNXR
|
X. tropicalis |
rxra
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CRISPR knockout of rxra (retinoid X receptor alpha ). Germ line transmission confirmed. Contact NXR... |
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Xtr.runx2emHorb
|
X. tropicalis |
runx2
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CRISPR knockout of runx2 (runt related transcription factor 2). Contact NXR to inquire about availab... |
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Xtr.runx1em3NXR
|
X. tropicalis |
runx1
|
CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani... |
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Xtr.runx1em2NXR
|
X. tropicalis |
runx1
|
CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani... |
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