|
Xtr.zbtb21emHorb
|
X.tropicalis |
zbtb21
|
CRISPR knockout of zbtb21(zinc finger and BTB domain containing 21), Current mosaic founders, Not te... |
NXR
|
Xtr.zbtb14emHorb
|
X.tropicalis |
zbtb14
|
CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Germ line transmission not yet... |
NXR
|
Xtr.wt1emHorb
|
X.tropicalis |
wt1
|
CRISPR knockout of wt1 (Wilms tumor 1). Not screened for germline transmission. |
NXR
|
Xtr.tyremNXR
|
X.tropicalis |
tyr
|
CRISPR knockout of tyr (tyrosinase), Confirmed germline transmission. Custom mutant generated by the... |
NXR
|
Xtr.tupmZimml
|
X.tropicalis |
unknown
|
Mutation affecting axial development identified in the Mill Hill screen of ENU-induced mutations. |
EXRC
|
Xtr.tspan8emHorb
|
X.tropicalis |
tspan8
|
CRISPR knockout of tspan8 (tetraspanin 8), Current mosaic founders, Not tested for germline transmis... |
NXR
|
Xtr.tp53em_del2/+_Vlemx
|
X.tropicalis |
tp53
|
Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deletio... |
|
Xtr.tp53em_del1/em_del2_Vlemx
|
X.tropicalis |
tp53
|
Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del... |
|
Xtr.tp53em_del1/+_Vlemx
|
X.tropicalis |
tp53
|
Deletion is expected to give rise to nonsense-mediated
decay since due to the frame-shifting deleti... |
|
Xtr.tlx3em2Horb
|
X.tropicalis |
tlx3
|
2nd CRISPR mutant line targeting tlx3 (T cell leukemia homeobox 3). Germ lIne transmission confirmed... |
NXR
|
Xtr.tlx3em1Horb
|
X.tropicalis |
tlx3
|
CRISPR knockout of tlx3 (T cell leukemia homeobox 3). Confirmed germline transmission. Custom mutant... |
NXR
|
Xtr.thratmShiyb
|
X.tropicalis |
|
This line was created using TALENS targeting exon 4 (the third coding exon) of the X. tropicalis thr... |
|
Xtr.tbxtemJcsm
|
X.tropicalis |
tbxt
|
Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ... |
EXRC
|
Xtr.tbxt.2em2Jcsm
|
X.tropicalis |
tbxt.2
|
Talen-induced mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... |
EXRC
|
Xtr.tbxt.2em1Jcsm
|
X.tropicalis |
tbxt.2
|
Talen-mediated mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... |
EXRC
|
Xtr.tbxt,tbxt.2emJcsm
|
X.tropicalis |
tbxt
|
Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in... |
EXRC
|
Xtr.tbx5emHorb
|
X.tropicalis |
tbx5
|
CRISPR knockout of tbx5 (T-box 5 ), Confirmed germline transmission. Custom mutant generated by Horb... |
NXR
|
Xtr.tbx2emHorb
|
X.tropicalis |
tbx2
|
CRISPR knockout of tbx2 (T-box 2), Current mosaic founders, Not tested for germline transmission. |
NXR
|
Xtr.sox3emHorb
|
X.tropicalis |
sox3
|
CRISPR knockout of sox3 (SRY-box 3), Current mosaic founders, Not tested for germline transmission. ... |
NXR
|
Xtr.smad4.1mZimml
|
X.tropicalis |
smad4
|
Mutation affecting haematopoiesis identified in a screen for ENU-induced mutations at Mill Hill. Pos... |
EXRC
|
Xtr.shroom3emHorb
|
X.tropicalis |
shroom3
|
CRISPR knockout of shroom3 (shroom family member 3), Current mosaic founders, Not tested for germlin... |
NXR
|
Xtr.rxrgemHorb
|
X.tropicalis |
rxrg
|
Description: CRISPR knockout of rxrg (retinoid X receptor gamma). Confirmed germline transmission. C... |
NXR
|
Xtr.rxrbemHorb
|
X.tropicalis |
rxrb
|
CRISPR knockout of rxrb (retinoid X receptor beta). Confirmed germline transmission. Custom mutant g... |
NXR
|
Xtr.runx1emHorb
|
X.tropicalis |
runx1
|
CRISPR knockout of runx1(runt related transcription factor 1). Current mosaic founders, not tested f... |
NXR
|
Xtr.runx1t1emHorb
|
X.tropicalis |
runx1t1
|
CRISPR knockout of runx1t1( RUNX1 translocation partner 1) gene. Germ line transmission not yet conf... |
NXR
|
Xtr.raxmGrngr
|
X.tropicalis |
rax
|
This mutant line was generated in an ENU screen from the Grainger lab by TILLING (Targeting Induced ... |
NXR
|
Xtr.prph2emHorb
|
X.tropicalis |
prph2
|
CRISPR knockout of prph2 (peripherin 2 (retinal degeneration, slow)). Confirmed germline transmissio... |
NXR
|
Xtr.pou3f4emHorb
|
X.tropicalis |
pou3f4
|
CRISPR knockout of pou3f4 (POU class 3 homeobox 4). Current mosaic founders, not tested for germline... |
NXR
|
Xtr.olig4emHorb
|
X.tropicalis |
olig4
|
CRISPR knockout of olig4 (oligodendrocyte transcription factor 4). Current mosaic founders, not test... |
NXR
|
Xtr.olig2emHorb
|
X.tropicalis |
olig2
|
CRISPR knockout of olig2 (oligodendrocyte lineage transcription factor 2). Confirmed germline transm... |
NXR
|
Xtr.npntinsZimml
|
X.tropicalis |
npnt
|
Nephronectin insertional mutation (probably null). Insertion of Tg(nkx2.5:GFP) transgene between 3rd... |
EXRC
|
Xtr.notch4emHorb
|
X.tropicalis |
notch4
|
CRISPR knockout of notch4. Confirmed germline transmission. |
NXR
|
Xtr.nhlh1emHorb
|
X.tropicalis |
nhlh1
|
CRISPR knockout of nhlh1 (nescient helix-loop-helix 1). Not screened for germline transmission. |
NXR
|
Xtr.myt1emHorb
|
X.tropicalis |
myt1
|
CRISPR knockout of myt1 (myelin transcription factor 1). Not tested for germline transmission. |
NXR
|
Xtr.mitfemHorb
|
X.tropicalis |
mitf
|
CRISPR knockout of mitf (melanocyte inducing transcription factor). Current mosaic founders, not tes... |
NXR
|
Xtr.map3k13emHorb
|
X.tropicalis |
map3k13
|
CRISPR knockout of map3k13 (mitogen-activated protein kinase kinase kinase 13). Confirmed germline t... |
NXR
|
Xtr.lmnaemHorb
|
X.tropicalis |
lmna
|
CRISPR knockout of lmna (lamin A/C).Confirmed germline transmission. Custom mutant generated by Horb... |
NXR
|
Xtr.legmZimml
|
X.tropicalis |
unknown
|
Mutation affecting otoconia formation identified in the Mill Hill screen of ENU-induced mutations. |
EXRC
|
Xtr.kng1emHorb
|
X.tropicalis |
kng1
|
CRISPR knockout of kng1(kininogen 1), Current mosaic founders, Not tested for germline transmission.... |
NXR
|
Xtr.junbemHorb
|
X.tropicalis |
junb
|
CRISPR knockout of junb (jun B proto-oncogene), Current mosaic founders, Not tested for germline tra... |
NXR
|
Xtr.insm2emHorb
|
X.tropicalis |
insm2
|
CRISPR knockout of insm2 (insulinoma-associated 2). Confirmed germline transmission. Custom mutant g... |
NXR
|
Xtr.hpse2emHorb
|
X.tropicalis |
hpse2
|
CRISPR knockout of hpse2 (heparanase 2 (inactive)). Confirmed germline transmission. Custom mutant g... |
NXR
|
Xtr.glis3emHorb
|
X.tropicalis |
glis3
|
CRISPR knockout of glis3 (GLIS family zinc finger 3). Confirmed germline transmission. Custom mutant... |
NXR
|
Xtr.gdf1emHorb
|
X.tropicalis |
gdf1
|
CRISPR knockout of gdf1 (growth differentiation factor 1). Confirmed germline transmission. Custom ... |
NXR
|
Xtr.frzb,frzb2emHorb
|
X.tropicalis |
frzb2
|
double CRISPR knockout of frzb (frizzled related protein ) and frzb2 (frizzled related protein 2). C... |
NXR
|
Xtr.foxc2emHorb
|
X.tropicalis |
foxc2
|
CRISPR knockout of foxc2 (forkhead box C2). Confirmed germline transmission. Custom mutant generate... |
NXR
|
Xtr.foxb1emHorb
|
X.tropicalis |
foxb1
|
CRISPR knockout of foxb1 (forkhead box B1 ), Current mosaic founders, Not tested for germline transm... |
NXR
|
Xtr.ezh2emHorb
|
X.tropicalis |
ezh2
|
CRISPR knockout of ezh2 (enhancer of zeste 2 polycomb repressive complex 2 subunit), Current mosaic ... |
NXR
|
Xtr.erfemHorb
|
X.tropicalis |
erf
|
CRISPR knockout of erf (ETS2 repressor factor). Confirmed germline transmission.
Custom mutant gene... |
NXR
|
Xtr.eomesemHorb
|
X.tropicalis |
eomes
|
CRISPR knockout of eomes (eomesodermin), Current mosaic founders, Not tested for germline transmissi... |
NXR
|
