Summary Attributions

Line Name: Xtr.tbxt,tbxt.2emJcsm

Line Images [+] show captions [-] hide captions Double Knockout tbtx and tbtx.2 mutant embryos Xtr.tbxt,tbxt.2{tmJcsm} at NF stage 26/27 (left) and NF stage 35/37 (right). Note the phenotype is lack of tailbud formation. tbxt/tbxt.2 double TALEN induced mutant X tropicalis embryos [Xtr.tbxt,tbxt.2{tmJcsm}] . showing the tail-less phenotype ( bottom ) compared to wildtype (top) and heterozygous (middle). Scale bar = 0.25mm

Summary
Synonym:	t (Xbra) -/+ t2 (Xbra3) -/+, Xtr.tbxt,tbxt.2tmJcsm,Xenopus tropicalis te1.2D/+t2e3.7D/+
Species:	Xenopus tropicalis
Background Strain:	Xtr.Outbred
Paternal Line:	Xtr.tbxtemJcsm
Maternal Line:	Xtr.tbxtemJcsm
Description:	Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in exon 3 of tbxt.2. Mutations are on the same chromosome, 30kb apart, so are inherited together.
Phenotype Description:	Tailess. Homozygous tailbud stage embryos tbxt (t, Xbra) -/- tbxt.2 (t2,Xbra3) -/- ) do not develop any tail.
Color Morph:
Breeding Type:	OUTBRED
Lab of Origin:	Smith Lab
Line Type:	Mutant
Mutated Gene(s):	tbxt
MTA Required:	No
Public:	Yes
Catalogue Number:

Stock Center	RRID	Generation	Availability	Mutant Details	Information
NXR (US)
EXRC (Europe)	EXRC_6021
NBRP (Japan)
XLRRI (US)

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