Summary Attributions

Line Name: Xtr.mlomZimml

Line Images [+] show captions [-] hide captions Xtr.mlo tadpole, also known as 'mrs lot' phenotype. ENU-mutants exhibits paralysis and motor neuron defects. Neural tissue of mlo and diploid control was stained with the HNK-1 antibody. In wild-type tadpoles motor neuron axons travel down the intermyotomal cleft from the neural tube; in mlo ([B] and [D]) the axonal tracts (black arrow) wander away from the intermyotomal space.

Summary
Synonym:	Mrs lot, mlo mh19 F3-C, T143-C, Xtr.mlo
Species:	Xenopus tropicalis
Background Strain:	Xtr.Nigerian 1EXRC
Paternal Line:
Maternal Line:
Color Morph:	pigmented
Phenotype Description:	Homozygous mutants are completely paralyzed with no heartbeat.
Breeding Type:	OUTBRED
Description:	Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. Maps to a genetic interval containing the titin (ttn) gene.
Lab of Origin:	Zimmerman Lab
Line Type:	Mutant
Mutated Gene:	unknown
MTA Required:	Yes
Public:	Yes
Catalogue Number:

Vendor	RRID	Availability
NXR (US):		No
EXRC (Europe):	EXRC_6012	Yes, order
NBRP (Japan):		No
XLRRI (US):		No
CRB (Europe):		No