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Summary Attributions Transgene

Line Name: Xla.Tg(rho:Eco.nfsA)Zuber

Line Images

Species: Xenopus laevis
Background Strain: Unknown
Paternal Line:
Maternal Line:
Color Morph: unknown
Phenotype Description: Expression pattern is best detected by in situ hybridization for nitroreductase transgene and is expressed specifically in rod photoreceptors Transgenic animals express nitroreductase in rod photoreceptors. Expression of the transgene has no deleterious effect on the development or survival of transgenic animals. However, addition of Metronidazole results in rapid, specific death of rod cells
Breeding Type: UNKNOWN
Description: rhodopsin (rho) promoter driving E. coli nitroreductase.Plasmid used for transgenesis (pXOP(-508/+41)-NTR) consists of the E. coli nitroreductase (NTR) expressed under the control of the Xenopus laevis rhodopsin promoter from Barry Knox. Base vector is pEGFP-N1 (Clontech) lacking CMV immediate early promoter & eGFP.
Lab of Origin: Zuber Lab
Line Type: Transgenic
Mutated Gene:
MTA Required: No
Public: Yes
Catalogue Number:

Vendor RRID Availability
NXR (US): NXR_0067 Yes, order
EXRC (Europe): No
NBRP (Japan): No
CRB (Europe): No