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Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney. , Zhang B., Development. March 22, 2018; 145 (6):
Renal localization and regulation by dietary phosphate of the MCT14 orphan transporter. , Knöpfel T., PLoS One. June 29, 2017; 12 (6): e0177942.
ROMK expression remains unaltered in a mouse model of familial hyperkalemic hypertension caused by the CUL3Δ403-459 mutation. , Murthy M., Physiol Rep. July 1, 2016; 4 (13):
Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3. , McCormick JA., J Clin Invest. November 1, 2014; 124 (11): 4723-36.
Insulin increases the functional activity of the renal NaCl cotransporter. , Chávez-Canales M., J Hypertens. February 1, 2013; 31 (2): 303-11.
A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo. , Oi K., Biol Open. February 15, 2012; 1 (2): 120-7.
Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone- SGK1- Nedd4-2 pathway. , Arroyo JP., J Am Soc Nephrol. September 1, 2011; 22 (9): 1707-19.
Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models. , Liu Z., Hum Mol Genet. March 1, 2011; 20 (5): 855-66.
Inversin relays Frizzled-8 signals to promote proximal pronephros development. , Lienkamp S ., Proc Natl Acad Sci U S A. November 23, 2010; 107 (47): 20388-93.
The activity of the thiazide-sensitive Na(+)-Cl(-) cotransporter is regulated by protein phosphatase PP4. , Glover M., Can J Physiol Pharmacol. October 1, 2010; 88 (10): 986-95.
Effects of dietary K on cell-surface expression of renal ion channels and transporters. , Frindt G., Am J Physiol Renal Physiol. October 1, 2010; 299 (4): F890-7.
The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice. , Leviel F., J Clin Invest. May 1, 2010; 120 (5): 1627-35.
Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway. , Rozansky DJ., J Clin Invest. September 1, 2009; 119 (9): 2601-12.
Renal Na+-K+-Cl- cotransporter activity and vasopressin-induced trafficking are lipid raft-dependent. , Welker P., Am J Physiol Renal Physiol. September 1, 2008; 295 (3): F789-802.
Surface expression of epithelial Na channel protein in rat kidney. , Frindt G., J Gen Physiol. June 1, 2008; 131 (6): 617-27.
Organization of the pronephric kidney revealed by large-scale gene expression mapping. , Raciti D ., Genome Biol. January 1, 2008; 9 (5): R84.
The prepattern transcription factor Irx3 directs nephron segment identity. , Reggiani L., Genes Dev. September 15, 2007; 21 (18): 2358-70.
WNK4 enhances TRPV5-mediated calcium transport: potential role in hypercalciuria of familial hyperkalemic hypertension caused by gene mutation of WNK4. , Jiang Y., Am J Physiol Renal Physiol. February 1, 2007; 292 (2): F545-54.
WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K+ channel ROMK1 ( Kir1.1). , Leng Q., J Physiol. March 1, 2006; 571 (Pt 2): 275-86.
Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform. , Subramanya AR., Am J Physiol Renal Physiol. March 1, 2006; 290 (3): F619-24.
WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis. , Rinehart J., Proc Natl Acad Sci U S A. November 15, 2005; 102 (46): 16777-82.
Effects of chemical chaperones on partially retarded NaCl cotransporter mutants associated with Gitelman's syndrome in a mouse cortical collecting duct cell line. , de Jong JC., Nephrol Dial Transplant. May 1, 2004; 19 (5): 1069-76.
WNK kinases regulate thiazide-sensitive Na-Cl cotransport. , Yang CL., J Clin Invest. April 1, 2003; 111 (7): 1039-45.
Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4. , Wilson FH., Proc Natl Acad Sci U S A. January 21, 2003; 100 (2): 680-4.
Interaction with grp58 increases activity of the thiazide-sensitive Na-Cl cotransporter. , Wyse B., Am J Physiol Renal Physiol. March 1, 2002; 282 (3): F424-30.