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Pharmacological characterization of a novel negative allosteric modulator of NMDA receptors, UBP792. , Sapkota K., Neuropharmacology. December 15, 2021; 201 108818.
Juvenile African Clawed Frogs (Xenopus laevis) Express Growth, Metamorphosis, Mortality, Gene Expression, and Metabolic Changes When Exposed to Thiamethoxam and Clothianidin. , Jenkins JA., Int J Mol Sci. December 10, 2021; 22 (24):
Eya1 protein distribution during embryonic development of Xenopus laevis. , Almasoudi SH., Gene Expr Patterns. December 1, 2021; 42 119213.
Distinct type II opsins in the eye decode light properties for background adaptation and behavioural background preference. , Bertolesi GE ., Mol Ecol. December 1, 2021; 30 (24): 6659-6676.
Galloway-Mowat syndrome: New insights from bioinformatics and expression during Xenopus embryogenesis. , Treimer E., Gene Expr Patterns. December 1, 2021; 42 119215.
Generation of a new six1-null line in Xenopus tropicalis for study of development and congenital disease. , Coppenrath K ., Genesis. December 1, 2021; 59 (12): e23453.
A missense mutation converts the Na+,K+-ATPase into an ion channel and causes therapy-resistant epilepsy. , Ygberg S., J Biol Chem. December 1, 2021; 297 (6): 101355.
Clustering of Aromatic Residues in Prion-like Domains Can Tune the Formation, State, and Organization of Biomolecular Condensates. , Holehouse AS., Biochemistry. November 30, 2021; 60 (47): 3566-3581.
Gene Structure Analysis of Chemokines and Their Receptors in Allotetraploid Frog, Xenopus laevis. , Fukui A ., Front Genet. November 25, 2021; 12 787979.
Identification of ZBTB26 as a Novel Risk Factor for Congenital Hypothyroidism. , Vick P ., Genes (Basel). November 24, 2021; 12 (12):
DNAJB6b-enriched small extracellular vesicles decrease polyglutamine aggregation in in vitro and in vivo models of Huntington disease. , Joshi BS., iScience. November 19, 2021; 24 (11): 103282.
Bacterial lipopolysaccharides can initiate regeneration of the Xenopus tadpole tail. , Bishop TF., iScience. November 19, 2021; 24 (11): 103281.
A convergent molecular network underlying autism and congenital heart disease. , Rosenthal SB., Cell Syst. November 17, 2021; 12 (11): 1094-1107.e6.
Pharmacological modulation of the cAMP signaling of two isoforms of melanocortin-3 receptor by melanocortin receptor accessory proteins in the tetrapod Xenopus laevis. , Xu Y ., Endocr Connect. November 15, 2021; 10 (11): 1477-1488.
The molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics. , Kollewe A., Elife. November 12, 2021; 10
Electrophysiological Approaches to Studying Normal and Abnormal Retinotectal Circuit Development in the Xenopus Tadpole. , Pratt KG ., Cold Spring Harb Protoc. November 1, 2021; 2021 (11):
Teriflunomide Promotes Oligodendroglial 8,9-Unsaturated Sterol Accumulation and CNS Remyelination. , Martin E., Neurol Neuroimmunol Neuroinflamm. November 1, 2021; 8 (6):
The early development and physiology of Xenopus laevis tadpole lateral line system. , Saccomanno V., J Neurophysiol. November 1, 2021; 126 (5): 1814-1830.
Deep learning is widely applicable to phenotyping embryonic development and disease. , Naert T., Development. November 1, 2021; 148 (21):
Structural basis of gating modulation of Kv4 channel complexes. , Kise Y., Nature. November 1, 2021; 599 (7883): 158-164.
Enhancing mask activity in dopaminergic neurons extends lifespan in flies. , Tian X., Aging Cell. November 1, 2021; 20 (11): e13493.
Physiological Functions of Thiol Peroxidases (Gpx1 and Prdx2) during Xenopus laevis Embryonic Development. , Lee H ., Antioxidants (Basel). October 17, 2021; 10 (10):
Green oxygen power plants in the brain rescue neuronal activity. , Özugur S., iScience. October 13, 2021; 24 (10): 103158.
Vestibular Influence on Vertebrate Skeletal Symmetry and Body Shape. , Gordy C., Front Syst Neurosci. October 6, 2021; 15 753207.
A role for zinc transporter gene SLC39A12 in the nervous system and beyond. , Davis DN., Gene. October 5, 2021; 799 145824.
Sodium-calcium exchanger mediates sensory-evoked glial calcium transients in the developing retinotectal system. , Benfey NJ., Cell Rep. October 5, 2021; 37 (1): 109791.
Everything in Modulation: Neuromodulators as Keys to Understanding Communication Dynamics. , Barkan CL., Integr Comp Biol. October 4, 2021; 61 (3): 854-866.
Function of chromatin modifier Hmgn1 during neural crest and craniofacial development. , Ihewulezi C., Genesis. October 1, 2021; 59 (10): e23447.
Analysis of M4 Transmembrane Segments in NMDA Receptor Function: A Negative Allosteric Modulatory Site at the GluN1 M4 is Determining the Efficiency of Neurosteroid Modulation. , Langer K., Front Pharmacol. October 1, 2021; 12 769046.
A Glutamate N-Methyl-d-Aspartate (NMDA) Receptor Subunit 2B-Selective Inhibitor of NMDA Receptor Function with Enhanced Potency at Acidic pH and Oral Bioavailability for Clinical Use. , Myers SJ., J Pharmacol Exp Ther. October 1, 2021; 379 (1): 41-52.
A glutamate concentration-biased allosteric modulator potentiates NMDA-induced ion influx in neurons. , Costa BM., Pharmacol Res Perspect. October 1, 2021; 9 (5): e00859.
Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease. , Getwan M ., Proc Natl Acad Sci U S A. September 28, 2021; 118 (39):
Polo-like kinase 1 (Plk1) regulates DNA replication origin firing and interacts with Rif1 in Xenopus. , Ciardo D., Nucleic Acids Res. September 27, 2021; 49 (17): 9851-9869.
The pyriproxyfen metabolite, 4'-OH-PPF, disrupts thyroid hormone signaling in neural stem cells, modifying neurodevelopmental genes affected by ZIKA virus infection. , Vancamp P., Environ Pollut. September 15, 2021; 285 117654.
Physical basis for distinct basal and mechanically gated activity of the human K+ channel TRAAK. , Rietmeijer RA., Neuron. September 15, 2021; 109 (18): 2902-2913.e4.
Ex Vivo Brain Preparation to Analyze Vocal Pathways of Xenopus Frogs. , Yamaguchi A ., Cold Spring Harb Protoc. September 1, 2021; 2021 (9):
Protein phosphatase 2A holoenzymes regulate leucine-rich repeat kinase 2 phosphorylation and accumulation. , Drouyer M., Neurobiol Dis. September 1, 2021; 157 105426.
A systemic cell cycle block impacts stage-specific histone modification profiles during Xenopus embryogenesis. , Pokrovsky D., PLoS Biol. September 1, 2021; 19 (9): e3001377.
BAC transgenic mice to study the expression of P2X2 and P2Y1 receptors. , Grohmann M., Purinergic Signal. September 1, 2021; 17 (3): 449-465.
The dual-specificity protein kinase Clk3 is essential for Xenopus neural development. , Virgirinia RP., Biochem Biophys Res Commun. August 27, 2021; 567 99-105.
The Role of RNA-Binding Proteins in Vertebrate Neural Crest and Craniofacial Development. , Forman TE., J Dev Biol. August 27, 2021; 9 (3):
Synthesis and Biological Evaluation of Novel Triazine Derivatives as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors. , Wang X ., J Med Chem. August 26, 2021; 64 (16): 12379-12396.
Modeling human congenital disorders with neural crest developmental defects using patient-derived induced pluripotent stem cells. , Okuno H., Regen Ther. August 24, 2021; 18 275-280.
Organization of DNA Replication Origin Firing in Xenopus Egg Extracts: The Role of Intra-S Checkpoint. , Ciardo D., Genes (Basel). August 9, 2021; 12 (8):
Unique variants in CLCN3, encoding an endosomal anion/proton exchanger, underlie a spectrum of neurodevelopmental disorders. , Duncan AR., Am J Hum Genet. August 5, 2021; 108 (8): 1450-1465.
GluN2A and GluN2B NMDA receptors use distinct allosteric routes. , Tian M., Nat Commun. August 5, 2021; 12 (1): 4709.
Retinol binding protein 1 affects Xenopus anterior neural development via all-trans retinoic acid signaling. , Flach H., Dev Dyn. August 1, 2021; 250 (8): 1096-1112.
Protein kinase D1 variant associated with human epilepsy and peripheral nerve hypermyelination. , Omer S., Clin Genet. August 1, 2021; 100 (2): 176-186.
Bisphenols disrupt thyroid hormone (TH) signaling in the brain and affect TH-dependent brain development in Xenopus laevis. , Niu Y., Aquat Toxicol. August 1, 2021; 237 105902.
Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod. , Alejevski F., Open Biol. August 1, 2021; 11 (8): 210065.