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Summary Anatomy Item Literature (5836) Expression Attributions Wiki
XB-ANAT-2

Papers associated with ectoderm (and lefty)

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Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR., Sempou E., Nat Commun. November 5, 2022; 13 (1): 6681.                                            

HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs., Liang T., Cell Rep. July 12, 2022; 40 (2): 111038.                              

Pinhead antagonizes Admp to promote notochord formation., Itoh K., iScience. May 7, 2021; 24 (6): 102520.                            

RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis., Kim H., Dev Cell. April 19, 2021; 56 (8): 1118-1130.e6.                                  

Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis., Ding Y., Proc Natl Acad Sci U S A. September 25, 2018; 115 (39): E9135-E9144.                    

An Early Function of Polycystin-2 for Left-Right Organizer Induction in Xenopus., Vick P., iScience. April 27, 2018; 2 76-85.                                        

Maternal Gdf3 is an obligatory cofactor in Nodal signaling for embryonic axis formation in zebrafish., Bisgrove BW., Elife. November 15, 2017; 6                 

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL., PLoS Biol. October 19, 2017; 15 (10): e2004045.                                              

Xenopus pitx3 target genes lhx1 and xnr5 are identified using a novel three-fluor flow cytometry-based analysis of promoter activation and repression., Hooker LN., Dev Dyn. September 1, 2017; 246 (9): 657-669.                    

Nodal signalling in Xenopus: the role of Xnr5 in left/right asymmetry and heart development., Tadjuidje E., Open Biol. August 1, 2016; 6 (8):             

E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation., Wills AE., Dev Cell. February 9, 2015; 32 (3): 345-57.                  

The Xenopus homologue of Down syndrome critical region protein 6 drives dorsoanterior gene expression and embryonic axis formation by antagonising polycomb group proteins., Li HY., Development. December 1, 2013; 140 (24): 4903-13.                                

Dvr1 transfers left-right asymmetric signals from Kupffer's vesicle to lateral plate mesoderm in zebrafish., Peterson AG., Dev Biol. October 1, 2013; 382 (1): 198-208.    

Developmental mechanisms directing early anterior forebrain specification in vertebrates., Andoniadou CL., Cell Mol Life Sci. October 1, 2013; 70 (20): 3739-52.        

TBX3 Directs Cell-Fate Decision toward Mesendoderm., Weidgang CE., Stem Cell Reports. August 29, 2013; 1 (3): 248-65.                

RFX2 is broadly required for ciliogenesis during vertebrate development., Chung MI., Dev Biol. March 1, 2012; 363 (1): 155-65.                                                          

Neurally Derived Tissues in Xenopus laevis Embryos Exhibit a Consistent Bioelectrical Left-Right Asymmetry., Pai VP., Stem Cells Int. January 1, 2012; 2012 353491.          

Distinct Xenopus Nodal ligands sequentially induce mesendoderm and control gastrulation movements in parallel to the Wnt/PCP pathway., Luxardi G., Development. February 1, 2010; 137 (3): 417-26.          

The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selection., Rosa A., Dev Cell. April 1, 2009; 16 (4): 517-27.    

Long-range action of Nodal requires interaction with GDF1., Tanaka C., Genes Dev. December 15, 2007; 21 (24): 3272-82.        

Xenopus Lefty requires proprotein cleavage but not N-linked glycosylation to inhibit nodal signaling., Westmoreland JJ., Dev Dyn. August 1, 2007; 236 (8): 2050-61.        

Evolution of axis specification mechanisms in jawed vertebrates: insights from a chondrichthyan., Coolen M., PLoS One. April 18, 2007; 2 (4): e374.              

Inhibitor-resistant type I receptors reveal specific requirements for TGF-beta signaling in vivo., Ho DM., Dev Biol. July 15, 2006; 295 (2): 730-42.            

Nodal-related gene Xnr5 is amplified in the Xenopus genome., Takahashi S., Genesis. July 1, 2006; 44 (7): 309-21.          

Formation of the ascidian epidermal sensory neurons: insights into the origin of the chordate peripheral nervous system., Pasini A., PLoS Biol. July 1, 2006; 4 (7): e225.              

Cooperative non-cell and cell autonomous regulation of Nodal gene expression and signaling by Lefty/Antivin and Brachyury in Xenopus., Cha YR., Dev Biol. February 15, 2006; 290 (2): 246-64.                        

The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo., Chen C., Development. January 1, 2006; 133 (2): 319-29.              

XCR2, one of three Xenopus EGF-CFC genes, has a distinct role in the regulation of left-right patterning., Onuma Y., Development. January 1, 2006; 133 (2): 237-50.                                      

Exploration of the extracellular space by a large-scale secretion screen in the early Xenopus embryo., Pera EM., Int J Dev Biol. January 1, 2005; 49 (7): 781-96.                                  

Xantivin suppresses the activity of EGF-CFC genes to regulate nodal signaling., Tanegashima K., Int J Dev Biol. June 1, 2004; 48 (4): 275-83.          

Regulation of nodal and BMP signaling by tomoregulin-1 (X7365) through novel mechanisms., Chang C., Dev Biol. March 1, 2003; 255 (1): 1-11.                    

PKCgamma regulates syndecan-2 inside-out signaling during xenopus left-right development., Kramer KL., Cell. December 27, 2002; 111 (7): 981-90.                

Lefty-dependent inhibition of Nodal- and Wnt-responsive organizer gene expression is essential for normal gastrulation., Branford WW., Curr Biol. December 23, 2002; 12 (24): 2136-41.              

Ectodermal syndecan-2 mediates left-right axis formation in migrating mesoderm as a cell-nonautonomous Vg1 cofactor., Kramer KL., Dev Cell. January 1, 2002; 2 (1): 115-24.  

Neural induction in the absence of mesoderm: beta-catenin-dependent expression of secreted BMP antagonists at the blastula stage in Xenopus., Wessely O., Dev Biol. June 1, 2001; 234 (1): 161-73.              

The pitx2 homeobox protein is required early for endoderm formation and nodal signaling. ., Faucourt M., Dev Biol. January 15, 2001; 229 (2): 287-306.                

Dickkopf1 and the Spemann-Mangold head organizer., Niehrs C., Int J Dev Biol. January 1, 2001; 45 (1): 237-40.    

Expression cloning of Xantivin, a Xenopus lefty/antivin-related gene, involved in the regulation of activin signaling during mesoderm induction., Tanegashima K., Mech Dev. December 1, 2000; 99 (1-2): 3-14.  

Expression of the zinc finger gene fez-like in zebrafish forebrain., Hashimoto H., Mech Dev. October 1, 2000; 97 (1-2): 191-5.

The lefty-related factor Xatv acts as a feedback inhibitor of nodal signaling in mesoderm induction and L-R axis development in xenopus., Cheng AM., Development. March 1, 2000; 127 (5): 1049-61.                

Zebrafish Dkk1 functions in forebrain specification and axial mesendoderm formation., Hashimoto H., Dev Biol. January 1, 2000; 217 (1): 138-52.  

Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos., Meno C., Genes Cells. August 1, 1997; 2 (8): 513-24.    

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