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Distinctive mechanisms of epilepsy-causing mutants discovered by measuring S4 movement in KCNQ2 channels. , Edmond MA., Elife. June 1, 2022; 11
Proteomic screen reveals diverse protein transport between connected neurons in the visual system. , Schiapparelli LM., Cell Rep. January 25, 2022; 38 (4): 110287.
A convergent molecular network underlying autism and congenital heart disease. , Rosenthal SB., Cell Syst. November 17, 2021; 12 (11): 1094-1107.e6.
Functional Integrity of Synapses in the Central Nervous System of Cognitively Intact Individuals with High Alzheimer's Disease Neuropathology Is Associated with Absence of Synaptic Tau Oligomers. , Singh A., J Alzheimers Dis. January 1, 2020; 78 (4): 1661-1678.
In silico re-engineering of a neurotransmitter to activate KCNQ potassium channels in an isoform-specific manner. , Manville RW., Commun Biol. January 1, 2019; 2 401.
Negative allosteric modulation of alpha 5-containing GABAA receptors engenders antidepressant-like effects and selectively prevents age-associated hyperactivity in tau-depositing mice. , Xu NZ., Psychopharmacology (Berl). April 1, 2018; 235 (4): 1151-1161.
Large, long range tensile forces drive convergence during Xenopus blastopore closure and body axis elongation. , Shook DR ., Elife. March 13, 2018; 7
Mechanism of functional interaction between potassium channel Kv1.3 and sodium channel NavBeta1 subunit. , Kubota T., Sci Rep. March 28, 2017; 7 45310.
Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption. , Jimah JR., Elife. December 1, 2016; 5
Selective inhibition of the kinase DYRK1A by targeting its folding process. , Kii I., Nat Commun. April 22, 2016; 7 11391.
A synergistic blocking effect of Mg²⁺ and spermine on the inward rectifier K⁺ (Kir2.1) channel pore. , Huang CW., Sci Rep. January 22, 2016; 6 21493.
Molecular Cloning and Functional Expression of the Equine K+ Channel KV11.1 (Ether à Go-Go-Related/KCNH2 Gene) and the Regulatory Subunit KCNE2 from Equine Myocardium. , Pedersen PJ., PLoS One. September 4, 2015; 10 (9): e0138320.
The active Hsc70/ tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics. , Fontaine SN., Hum Mol Genet. July 15, 2015; 24 (14): 3971-81.
Microtubule-associated protein tau promotes neuronal class II β-tubulin microtubule formation and axon elongation in embryonic Xenopus laevis. , Liu Y ., Eur J Neurosci. May 1, 2015; 41 (10): 1263-75.
Paxilline inhibits BK channels by an almost exclusively closed-channel block mechanism. , Zhou Y., J Gen Physiol. November 1, 2014; 144 (5): 415-40.
FAK is required for tension-dependent organization of collective cell movements in Xenopus mesendoderm. , Bjerke MA., Dev Biol. October 15, 2014; 394 (2): 340-56.
Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channel. , Zaydman MA., Elife. March 12, 2014; 3 e03606.
Comparative expression analysis of cysteine-rich intestinal protein family members crip1, 2 and 3 during Xenopus laevis embryogenesis. , Hempel A., Int J Dev Biol. January 1, 2014; 58 (10-12): 841-9.
c- Jun N-terminal kinase phosphorylation of heterogeneous nuclear ribonucleoprotein K regulates vertebrate axon outgrowth via a posttranscriptional mechanism. , Hutchins EJ ., J Neurosci. September 11, 2013; 33 (37): 14666-80.
Conformational changes in the lower palm domain of ASIC1a contribute to desensitization and RFamide modulation. , Frey EN., PLoS One. August 12, 2013; 8 (8): e71733.
Imbalance of Hsp70 family variants fosters tau accumulation. , Jinwal UK., FASEB J. April 1, 2013; 27 (4): 1450-9.
Heterogeneous nuclear ribonucleoprotein K, an RNA-binding protein, is required for optic axon regeneration in Xenopus laevis. , Liu Y ., J Neurosci. March 7, 2012; 32 (10): 3563-74.
Asymmetric divergence in structure and function of HCN channel duplicates in Ciona intestinalis. , Jackson HA., PLoS One. January 1, 2012; 7 (11): e47590.
State-independent intracellular access of quaternary ammonium blockers to the pore of TREK-1. , Rapedius M., Channels (Austin). January 1, 2012; 6 (6): 473-8.
hnRNP K post-transcriptionally co-regulates multiple cytoskeletal genes needed for axonogenesis. , Liu Y ., Development. July 1, 2011; 138 (14): 3079-90.
Identification of the pre-T-cell receptor alpha chain in nonmammalian vertebrates challenges the structure-function of the molecule. , Smelty P., Proc Natl Acad Sci U S A. November 16, 2010; 107 (46): 19991-6.
Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A. , Ogawa Y., Nat Commun. October 5, 2010; 1 86.
Macroscopic stiffening of embryonic tissues via microtubules, RhoGEF and the assembly of contractile bundles of actomyosin. , Zhou J., Development. August 1, 2010; 137 (16): 2785-94.
MID1 and MID2 are required for Xenopus neural tube closure through the regulation of microtubule organization. , Suzuki M ., Development. July 1, 2010; 137 (14): 2329-39.
Fast and slow voltage sensor rearrangements during activation gating in Kv1.2 channels detected using tetramethylrhodamine fluorescence. , Horne AJ., J Gen Physiol. July 1, 2010; 136 (1): 83-99.
Development of a sensitive non-radioactive protein kinase assay and its application for detecting DYRK activity in Xenopus laevis oocytes. , Lilienthal E., BMC Biochem. May 20, 2010; 11 20.
Multiple intermediate states precede pore block during N-type inactivation of a voltage-gated potassium channel. , Prince-Carter A., J Gen Physiol. July 1, 2009; 134 (1): 15-34.
Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6. , Wu G., PLoS One. January 1, 2009; 4 (3): e4926.
Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells. , Park TJ., Nat Genet. July 1, 2008; 40 (7): 871-9.
Characterization of fetal and postnatal enteric neuronal cell lines with improvement in intestinal neural function. , Anitha M., Gastroenterology. May 1, 2008; 134 (5): 1424-35.
Developmental regulation of central spindle assembly and cytokinesis during vertebrate embryogenesis. , Kieserman EK ., Curr Biol. January 22, 2008; 18 (2): 116-23.
H bonding at the helix-bundle crossing controls gating in Kir potassium channels. , Rapedius M., Neuron. August 16, 2007; 55 (4): 602-14.
Anisotropic diffusion of metabolites in peripheral nerve using diffusion weighted magnetic resonance spectroscopy at ultra-high field. , Ellegood J., J Magn Reson. January 1, 2007; 184 (1): 20-8.
Differential role of 14-3-3 family members in Xenopus development. , Lau JM., Dev Dyn. July 1, 2006; 235 (7): 1761-76.
Role of charged residues in the S1-S4 voltage sensor of BK channels. , Ma Z., J Gen Physiol. March 1, 2006; 127 (3): 309-28.
Expression and functional characterization of the human ether-à- go-go-related gene ( HERG) K+ channel cardiac splice variant in Xenopus laevis oocytes. , Aydar E., J Membr Biol. January 1, 2006; 211 (2): 115-26.
Multiprotein assembly of Kv4.2, KChIP3 and DPP10 produces ternary channel complexes with ISA-like properties. , Jerng HH., J Physiol. November 1, 2005; 568 (Pt 3): 767-88.
The circadian clock-containing photoreceptor cells in Xenopus laevis express several isoforms of casein kinase I. , Constance CM ., Brain Res Mol Brain Res. May 20, 2005; 136 (1-2): 199-211.
Hysteresis in the voltage dependence of HCN channels: conversion between two modes affects pacemaker properties. , Männikkö R., J Gen Physiol. March 1, 2005; 125 (3): 305-26.
Perturbation analysis of the voltage-sensitive conformational changes of the Na+/glucose cotransporter. , Loo DD., J Gen Physiol. January 1, 2005; 125 (1): 13-36.
Lidocaine: a foot in the door of the inner vestibule prevents ultra-slow inactivation of a voltage-gated sodium channel. , Sandtner W., Mol Pharmacol. September 1, 2004; 66 (3): 648-57.
Cell-type-specific splicing of KChIP4 mRNA correlates with slower kinetics of A-type current. , Baranauskas G., Eur J Neurosci. July 1, 2004; 20 (2): 385-91.
Activation and desensitization of the recombinant P2X1 receptor at nanomolar ATP concentrations. , Rettinger J ., J Gen Physiol. May 1, 2003; 121 (5): 451-61.
Negative charges in the DIII-DIV linker of human skeletal muscle Na+ channels regulate deactivation gating. , Groome JR ., J Physiol. April 1, 2003; 548 (Pt 1): 85-96.
Fluorescent labeling of endothelial cells allows in vivo, continuous characterization of the vascular development of Xenopus laevis. , Levine AJ., Dev Biol. February 1, 2003; 254 (1): 50-67.