Papers associated with whole organism (and lrp6)

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	R-Spondin 2 governs Xenopus left-right body axis formation by establishing an FGF signaling gradient., Lee H, Lee H., Nat Commun. February 2, 2024; 15 (1): 1003.
	The early dorsal signal in vertebrate embryos requires endolysosomal membrane trafficking., Azbazdar Y., Bioessays. January 1, 2024; 46 (1): e2300179.
	The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH., Nat Commun. October 5, 2023; 14 (1): 6173.
	ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer., Pandey A., Front Cell Dev Biol. January 1, 2023; 11 1271178.
	Maternal Wnt11b regulates cortical rotation during Xenopus axis formation: analysis of maternal-effect wnt11b mutants., Houston DW., Development. September 1, 2022; 149 (17):
	Lysosomes are required for early dorsal signaling in the Xenopus embryo., Tejeda-Muñoz N., Proc Natl Acad Sci U S A. April 26, 2022; 119 (17): e2201008119.
	The role of Xenopus developmental biology in unraveling Wnt signalling and antero-posterior axis formation., Niehrs C., Dev Biol. February 1, 2022; 482 1-6.
	Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd., Lee H, Lee H., J Biol Chem. February 1, 2022; 298 (2): 101586.
	LRP6 Receptor Plays Essential Functions in Development and Human Diseases., Alrefaei AF., Genes (Basel). January 10, 2022; 13 (1):
	Signaling Control of Mucociliary Epithelia: Stem Cells, Cell Fates, and the Plasticity of Cell Identity in Development and Disease., Walentek P., Cells Tissues Organs. January 1, 2022; 211 (6): 736-753.
	A catenin of the plakophilin-subfamily, Pkp3, responds to canonical-Wnt pathway components and signals., Hong JY., Biochem Biophys Res Commun. July 23, 2021; 563 31-39.
	Purified Bighead protein efficiently promotes head development in the South African clawed frog, Xenopus laevis., Colozza G., MicroPubl Biol. January 5, 2021; 2021
	R-spondins are BMP receptor antagonists in Xenopus early embryonic development., Lee H, Lee H., Nat Commun. November 4, 2020; 11 (1): 5570.
	TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M., Elife. September 14, 2020; 9
	The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer., Chang LS., Elife. January 14, 2020; 9
	Crystal structure of a mammalian Wnt-frizzled complex., Hirai H., Nat Struct Mol Biol. May 1, 2019; 26 (5): 372-379.
	Maternal Huluwa dictates the embryonic body axis through β-catenin in vertebrates., Yan L., Science. November 23, 2018; 362 (6417):
	Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis., Ding Y., Proc Natl Acad Sci U S A. September 25, 2018; 115 (39): E9135-E9144.
	Head formation requires Dishevelled degradation that is mediated by March2 in concert with Dapper1., Lee H, Lee H., Development. April 10, 2018; 145 (7):
	PAWS1 controls Wnt signalling through association with casein kinase 1α., Bozatzi P., EMBO Rep. April 1, 2018; 19 (4):
	Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus., Mii Y., Nat Commun. December 7, 2017; 8 (1): 1973.
	Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Kirsch N., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.
	The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning., Rauschenberger V., Development. June 15, 2017; 144 (12): 2234-2247.
	Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling., Han W., Sci Rep. February 15, 2017; 7 42590.
	Apolipoprotein C-I mediates Wnt/Ctnnb1 signaling during neural border formation and is required for neural crest development., Yokota C., Int J Dev Biol. January 1, 2017; 61 (6-7): 415-425.
	Capsaicin inhibits the Wnt/β-catenin signaling pathway by down-regulating PP2A., Park DS., Biochem Biophys Res Commun. September 9, 2016; 478 (1): 455-461.
	Spatial and temporal aspects of Wnt signaling and planar cell polarity during vertebrate embryonic development., Sokol SY., Semin Cell Dev Biol. June 1, 2015; 42 78-85.
	Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation., Zhang X., Dev Cell. March 23, 2015; 32 (6): 719-30.
	Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism., Haramoto Y., Sci Rep. January 12, 2015; 5 11603.
	A Molecular atlas of Xenopus respiratory system development., Rankin SA, Rankin SA., Dev Dyn. January 1, 2015; 244 (1): 69-85.
	Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway., Amado NG., J Biol Chem. December 19, 2014; 289 (51): 35456-67.
	Getting to know your neighbor: cell polarization in early embryos., Nance J., J Cell Biol. September 29, 2014; 206 (7): 823-32.
	In vivo analysis of formation and endocytosis of the Wnt/β-catenin signaling complex in zebrafish embryos., Hagemann AI., J Cell Sci. September 15, 2014; 127 (Pt 18): 3970-82.
	Cholesterol selectively activates canonical Wnt signalling over non-canonical Wnt signalling., Sheng R., Nat Commun. July 15, 2014; 5 4393.
	Polarized Wnt signaling regulates ectodermal cell fate in Xenopus., Huang YL., Dev Cell. April 28, 2014; 29 (2): 250-7.
	The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength., de Lau W., Genes Dev. February 15, 2014; 28 (4): 305-16.
	PTK7 modulates Wnt signaling activity via LRP6., Bin-Nun N., Development. January 1, 2014; 141 (2): 410-21.
	RAB8B is required for activity and caveolar endocytosis of LRP6., Demir K., Cell Rep. September 26, 2013; 4 (6): 1224-34.
	Lypd6 enhances Wnt/β-catenin signaling by promoting Lrp6 phosphorylation in raft plasma membrane domains., Özhan G., Dev Cell. August 26, 2013; 26 (4): 331-45.
	structural Studies of Wnts and identification of an LRP6 binding site., Chu ML., Structure. July 2, 2013; 21 (7): 1235-42.
	The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling., Wang F., Dev Biol. July 1, 2013; 379 (1): 16-27.
	Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling., Park DS., Biochem Biophys Res Commun. June 28, 2013; 436 (2): 338-43.
	Single blastomere expression profiling of Xenopus laevis embryos of 8 to 32-cells reveals developmental asymmetry., Flachsova M., Sci Rep. January 1, 2013; 3 2278.
	Essential role of AWP1 in neural crest specification in Xenopus., Seo JH., Int J Dev Biol. January 1, 2013; 57 (11-12): 829-36.
	Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation., Zhang X., Cell. June 22, 2012; 149 (7): 1565-77.
	Maternal xNorrin, a canonical Wnt signaling agonist and TGF-β antagonist, controls early neuroectoderm specification in Xenopus., Xu S., PLoS Biol. January 1, 2012; 10 (3): e1001286.
	Cortical rotation and messenger RNA localization in Xenopus axis formation., Houston DW., Wiley Interdiscip Rev Dev Biol. January 1, 2012; 1 (3): 371-88.
	Waif1/5T4 inhibits Wnt/β-catenin signaling and activates noncanonical Wnt pathways by modifying LRP6 subcellular localization., Kagermeier-Schenk B., Dev Cell. December 13, 2011; 21 (6): 1129-43.
	Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation., Liang J., Mol Cell Biol. July 1, 2011; 31 (13): 2577-90.
	Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development., Paulsen M., Proc Natl Acad Sci U S A. June 21, 2011; 108 (25): 10202-7.

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