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GABAA receptor function is enhanced by Interleukin-10 in human epileptogenic gangliogliomas and its effect is counteracted by Interleukin-1β. , Ruffolo G., Sci Rep. October 26, 2022; 12 (1): 17956.
Picrotoxin Delineates Different Transport Configurations for Malate and γ Aminobutyric Acid through TaALMT1. , Ramesh SA., Biology (Basel). August 2, 2022; 11 (8):
Sea anemone Bartholomea annulata venom inhibits voltage-gated Na+ channels and activates GABAA receptors from mammals. , Colom-Casasnovas A., Sci Rep. March 30, 2022; 12 (1): 5352.
Dissecting the Molecular Determinants of GABAA Receptors Current Rundown, a Hallmark of Refractory Human Epilepsy. , Cifelli P., Brain Sci. March 30, 2021; 11 (4):
Characterization of the GABRB2-Associated Neurodevelopmental Disorders. , El Achkar CM., Ann Neurol. March 1, 2021; 89 (3): 573-586.
A critical residue in the α1M2-M3 linker regulating mammalian GABAA receptor pore gating by diazepam. , Nors JW., Elife. February 16, 2021; 10
GABAA Receptors Expressed in Oligodendrocytes Cultured from the Neonatal Rat Contain α3 and γ1 Subunits and Present Differential Functional and Pharmacological Properties. , Ordaz RP., Mol Pharmacol. February 1, 2021; 99 (2): 133-146.
GABAA Receptor Subunit Composition Drives Its Sensitivity to the Insecticide Fipronil. , Soualah Z., Front Neurosci. January 1, 2021; 15 768466.
PNU-120596, a positive allosteric modulator of mammalian α7 nicotinic acetylcholine receptor, is a negative modulator of ligand-gated chloride-selective channels of the gastropod Lymnaea stagnalis. , Vulfius CA., J Neurochem. November 1, 2020; 155 (3): 274-284.
The desensitization pathway of GABAA receptors, one subunit at a time. , Gielen M., Nat Commun. October 23, 2020; 11 (1): 5369.
Functional characterization of the antiepileptic drug candidate, padsevonil, on GABAA receptors. , Niespodziany I., Epilepsia. May 1, 2020; 61 (5): 914-923.
Reduced neurosteroid potentiation of GABAA receptors in epilepsy and depolarized hippocampal neurons. , Joshi S., Ann Clin Transl Neurol. April 1, 2020; 7 (4): 527-542.
The effects of a competitive antagonist on GABA-evoked currents in the presence of sedative-hypnotic agents. , McGrath M., Pharmacol Rep. February 1, 2020; 72 (1): 260-266.
Competitive Antagonism of Etomidate Action by Diazepam. , McGrath M., Anesthesiology. January 1, 2020; 133 (3): 583-594.
Drug-selective Anesthetic Insensitivity of Zebrafish Lacking γ-Aminobutyric Acid Type A Receptor β3 Subunits. , Yang X., Anesthesiology. December 1, 2019; 131 (6): 1276-1291.
A FLIPR Assay for Discovery of GABAA Receptor Modulators of Natural Origin. , Faleschini MT., Planta Med. August 1, 2019; 85 (11-12): 925-933.
Involvement of the GABAA receptor α subunit in the mode of action of etifoxine. , Mattei C., Pharmacol Res. July 1, 2019; 145 104250.
In vitro and in vivo GABAA Receptor Interaction of the Propanidid Metabolite 4-(2-[Diethylamino]-2-Oxoethoxy)-3-Methoxy-Benzeneacetic Acid. , Cenani A., Pharmacology. January 1, 2019; 103 (1-2): 10-16.
Etomidate and Etomidate Analog Binding and Positive Modulation of γ-Aminobutyric Acid Type A Receptors: Evidence for a State-dependent Cutoff Effect. , McGrath M., Anesthesiology. November 1, 2018; 129 (5): 959-969.
Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission. , Knoflach F., J Vis Exp. August 16, 2018; (138):
Differential modulation of human GABAC-ρ1 receptor by sulfur-containing compounds structurally related to taurine. , Ochoa-de la Paz LD., BMC Neurosci. August 3, 2018; 19 (1): 47.
Direct neurotransmitter activation of voltage-gated potassium channels. , Manville RW., Nat Commun. May 10, 2018; 9 (1): 1847.
Towards functional selectivity for α6β3γ2 GABAA receptors: a series of novel pyrazoloquinolinones. , Treven M., Br J Pharmacol. February 1, 2018; 175 (3): 419-428.
Diversity of Nicotinic Acetylcholine Receptor Positive Allosteric Modulators Revealed by Mutagenesis and a Revised Structural Model. , Newcombe J., Mol Pharmacol. February 1, 2018; 93 (2): 128-140.
Expression and purification of a functional heteromeric GABAA receptor for structural studies. , Claxton DP., PLoS One. January 1, 2018; 13 (7): e0201210.
The novel isoxazoline ectoparasiticide lotilaner (Credelio™): a non-competitive antagonist specific to invertebrates γ-aminobutyric acid-gated chloride channels (GABACls). , Rufener L., Parasit Vectors. November 1, 2017; 10 (1): 530.
Assembly rules for GABAA receptor complexes in the brain. , Martenson JS., Elife. August 17, 2017; 6
Anesthetic synergy between two n-alkanes. , Brosnan RJ., Vet Anaesth Analg. May 1, 2017; 44 (3): 577-588.
GABAB receptor attenuation of GABAA currents in neurons of the mammalian central nervous system. , Shen W., Physiol Rep. March 1, 2017; 5 (6):
The Effect of 4-hydroxybenzaldehyde on the γ-aminobutyric Acid Type A Receptor. , Zhang J., Malays J Med Sci. March 1, 2017; 24 (2): 94-99.
Preclinical development of moxidectin as a novel therapeutic for alcohol use disorder. , Huynh N., Neuropharmacology. February 1, 2017; 113 (Pt A): 60-70.
Low Expression in Xenopus Oocytes and Unusual Functional Properties of α1β2γ2 GABAA Receptors with Non-Conventional Subunit Arrangement. , Baur R., PLoS One. January 3, 2017; 12 (1): e0170572.
Xenopus Oocytes: Optimized Methods for Microinjection, Removal of Follicular Cell Layers, and Fast Solution Changes in Electrophysiological Experiments. , Maldifassi MC., J Vis Exp. December 31, 2016; (118):
Cannabis in epilepsy: From clinical practice to basic research focusing on the possible role of cannabidivarin. , Morano A., Epilepsia Open. September 19, 2016; 1 (3-4): 145-151.
Zolpidem is a potent stoichiometry-selective modulator of α1β3 GABAA receptors: evidence of a novel benzodiazepine site in the α1-α1 interface. , Che Has AT., Sci Rep. June 27, 2016; 6 28674.
Correction for Inhibition Leads to an Allosteric Co-Agonist Model for Pentobarbital Modulation and Activation of α1β3γ2L GABAA Receptors. , Ziemba AM., PLoS One. April 21, 2016; 11 (4): e0154031.
Potentiating effect of glabridin from Glycyrrhiza glabra on GABAA receptors. , Hoffmann KM., Biochem Biophys Rep. March 31, 2016; 6 197-202.
Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels. , Bertozzi C., PLoS Biol. March 4, 2016; 14 (3): e1002393.
Pharmacological induction of skin pigmentation unveils the neuroendocrine circuit regulated by light. , Bertolesi GE ., Pigment Cell Melanoma Res. March 1, 2016; 29 (2): 186-98.
Propofol and AZD3043 Inhibit Adult Muscle and Neuronal Nicotinic Acetylcholine Receptors Expressed in Xenopus Oocytes. , Jonsson Fagerlund M., Pharmaceuticals (Basel). February 6, 2016; 9 (1):
Identification of the putative binding pocket of valerenic acid on GABAA receptors using docking studies and site-directed mutagenesis. , Luger D., Br J Pharmacol. November 1, 2015; 172 (22): 5403-13.
The Direct Actions of GABA, 2'-Methoxy-6-Methylflavone and General Anaesthetics at β3γ2L GABAA Receptors: Evidence for Receptors with Different Subunit Stoichiometries. , Chua HC., PLoS One. October 20, 2015; 10 (10): e0141359.
Interactions of L-3,5,3'-Triiodothyronine [corrected], Allopregnanolone, and Ivermectin with the GABAA Receptor: Evidence for Overlapping Intersubunit Binding Modes. , Westergard T., PLoS One. September 4, 2015; 10 (9): e0139072.
GABA signalling modulates plant growth by directly regulating the activity of plant-specific anion transporters. , Ramesh SA., Nat Commun. July 29, 2015; 6 7879.
Identification of amino acids involved in histamine potentiation of GABA A receptors. , Thiel U., Front Pharmacol. May 26, 2015; 6 106.
MmTX1 and MmTX2 from coral snake venom potently modulate GABAA receptor activity. , Rosso JP., Proc Natl Acad Sci U S A. February 24, 2015; 112 (8): E891-900.
Identification of dehydroabietc acid from Boswellia thurifera resin as a positive GABAA receptor modulator. , Rueda DC., Fitoterapia. December 1, 2014; 99 28-34.
Phosphatidylinositol 4,5-bisphosphate depletion fails to affect neurosteroid modulation of GABAA receptor function. , Mennerick S., Psychopharmacology (Berl). September 1, 2014; 231 (17): 3493-501.
Engineering a light-regulated GABAA receptor for optical control of neural inhibition. , Lin WC., ACS Chem Biol. July 18, 2014; 9 (7): 1414-9.
Esters of valerenic acid as potential prodrugs. , Hintersteiner J., Eur J Pharmacol. July 15, 2014; 735 123-31.