Results 1 - 50 of 603 results
CIROZ is dispensable in ancestral vertebrates but essential for left- right patterning in humans. , Szenker-Ravi E., Am J Hum Genet. January 6, 2025; 112 (2): 353-373.
Proliferation associated 2G4 is required for the ciliation of vertebrate motile cilia. , Lee M., Commun Biol. November 4, 2024; 7 (1): 1430.
The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation. , Kulkarni SS ., Cytoskeleton (Hoboken). October 31, 2024;
CC2D1A causes ciliopathy, intellectual disability, heterotaxy, renal dysplasia, and abnormal CSF flow. , Kim AH., Life Sci Alliance. October 21, 2024; 7 (10):
Dzip1 is dynamically expressed in the vertebrate germline and regulates the development of Xenopus primordial germ cells. , Turgeon A., Dev Biol. October 1, 2024; 514 28-36.
Actin Depolymerizing Factor Destrin Regulates Cilia Development and Function during Vertebrate Embryogenesis. , Kim Y., Dev Reprod. September 30, 2024; 28 (3): 109-119.
The FAM13A Long Isoform Regulates Cilia Movement and Co-ordination in Airway Mucociliary Transport. , Howes A., Am J Respir Cell Mol Biol. September 1, 2024; 71 (3): 282-293.
The binding of LARP6 and DNAAF6 in biomolecular condensates influences ciliogenesis of multiciliated cells. , Earwood R., J Biol Chem. June 1, 2024; 300 (6): 107373.
Mebendazole preferentially inhibits cilia formation and exerts anticancer activity by synergistically augmenting DNA damage. , Hong J., Biomed Pharmacother. May 1, 2024; 174 116434.
S100Z is expressed in a lateral subpopulation of olfactory receptor neurons in the main olfactory system of Xenopus laevis. , Kahl M., Dev Neurobiol. April 1, 2024; 84 (2): 59-73.
A vertebrate Vangl2 translational variant required for planar cell polarity. , Walton A., J Biol Chem. April 1, 2024; 300 (4): 106792.
Crb3 is required to organize the apical domain of multiciliated cells. , Burcklé C., J Cell Sci. March 1, 2024; 137 (5):
Label-free proteomic comparison reveals ciliary and nonciliary phenotypes of IFT-A mutants. , Leggere JC., Mol Biol Cell. March 1, 2024; 35 (3): ar39.
R-Spondin 2 governs Xenopus left- right body axis formation by establishing an FGF signaling gradient. , Lee H ., Nat Commun. February 2, 2024; 15 (1): 1003.
Early life exposure to perfluorooctanesulfonate (PFOS) impacts vital biological processes in Xenopus laevis: Integrated morphometric and transcriptomic analyses. , Ismail T., Ecotoxicol Environ Saf. January 1, 2024; 269 115820.
TBC1D32 variants disrupt retinal ciliogenesis and cause retinitis pigmentosa. , Bocquet B., JCI Insight. November 8, 2023; 8 (21):
Bidirectional multiciliated cell extrusion is controlled by Notch-driven basal extrusion and Piezo1-driven apical extrusion. , Ventrella R., Development. September 1, 2023; 150 (17):
Ruvbl1 is Essential for Ciliary Beating during Xenopus laevis Embryogenesis. , Kim CY., Dev Reprod. September 1, 2023; 27 (3): 159-165.
The histone H4K20 methyltransferase SUV4-20H1/KMT5B is required for multiciliated cell differentiation in Xenopus. , Angerilli A., Life Sci Alliance. July 1, 2023; 6 (7):
CFAP45, a heterotaxy and congenital heart disease gene, affects cilia stability. , Deniz E ., Dev Biol. July 1, 2023; 499 75-88.
Calcium dynamics at the neural cell primary cilium regulate Hedgehog signaling-dependent neurogenesis in the embryonic neural tube. , Shim S ., Proc Natl Acad Sci U S A. June 6, 2023; 120 (23): e2220037120.
Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease. , Mishra-Gorur K., Proc Natl Acad Sci U S A. April 18, 2023; 120 (16): e2214997120.
A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development. , Lee J ., Sci Adv. April 7, 2023; 9 (14): eadd5745.
Label-free proteomic comparison reveals ciliary and non-ciliary phenotypes of IFT-A mutants. , Leggere JC., bioRxiv. March 9, 2023;
Kif9 is an active kinesin motor required for ciliary beating and proximodistal patterning of motile axonemes. , Konjikusic MJ., J Cell Sci. March 1, 2023; 136 (5):
Ckb and Ybx2 interact with Ribc2 and are necessary for the ciliary beating of multi- cilia. , Kwon KY., Genes Genomics. February 1, 2023; 45 (2): 157-167.
Ordered deployment of distinct ciliary beating machines in growing axonemes of vertebrate multiciliated cells. , Lee C ., Differentiation. January 1, 2023; 131 49-58.
Expression and cilia associated localization of Histone deacetylases 6 in Xenopus. , Tisler M., MicroPubl Biol. January 1, 2023; 2023
INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex. , Mascibroda LG., Nat Commun. October 13, 2022; 13 (1): 6054.
GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base. , Jang DG., Elife. August 25, 2022; 11
Development of a multiciliated cell. , Mahjoub MR., Curr Opin Cell Biol. August 1, 2022; 77 102105.
Evo-Devo of Urbilateria and its larval forms. , De Robertis EM ., Dev Biol. July 1, 2022; 487 10-20.
Cilia-localized GID/CTLH ubiquitin ligase complex regulates protein homeostasis of sonic hedgehog signaling components. , Hantel F., J Cell Sci. May 1, 2022; 135 (9):
Male infertility-associated Ccdc108 regulates multiciliogenesis via the intraflagellar transport machinery. , Zhao H ., EMBO Rep. April 5, 2022; 23 (4): e52775.
TPX2 is a prognostic marker and promotes cell proliferation in neuroblastoma. , Koike Y., Oncol Lett. April 1, 2022; 23 (4): 136.
Lrrcc1 and Ccdc61 are conserved effectors of multiciliated cell function. , Nommick A., J Cell Sci. February 15, 2022; 135 (4):
PCD Genes-From Patients to Model Organisms and Back to Humans. , Niziolek M., Int J Mol Sci. February 3, 2022; 23 (3):
CEP97 phosphorylation by Dyrk1a is critical for centriole separation during multiciliogenesis. , Lee M., J Cell Biol. January 3, 2022; 221 (1):
Discovery of a genetic module essential for assigning left- right asymmetry in humans and ancestral vertebrates. , Szenker-Ravi E., Nat Genet. January 1, 2022; 54 (1): 62-72.
dmrt2 and myf5 Link Early Somitogenesis to Left- Right Axis Determination in Xenopus laevis. , Tingler M., Front Cell Dev Biol. January 1, 2022; 10 858272.
Abnormal left- right organizer and laterality defects in Xenopus embryos after formin inhibitor SMIFH2 treatment. , Petri N., PLoS One. January 1, 2022; 17 (11): e0275164.
Kinematic self-replication in reconfigurable organisms. , Kriegman S., Proc Natl Acad Sci U S A. December 7, 2021; 118 (49):
Fluid Mechanics of Mosaic Ciliated Tissues. , Boselli F., Phys Rev Lett. November 5, 2021; 127 (19): 198102.
Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease. , Getwan M ., Proc Natl Acad Sci U S A. September 28, 2021; 118 (39):
Bicc1 and Dicer regulate left- right patterning through post-transcriptional control of the Nodal inhibitor Dand5. , Maerker M., Nat Commun. September 16, 2021; 12 (1): 5482.
A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts. , Grosch M., J Cell Sci. August 15, 2021; 134 (16):
ZC3HC1 Is a Novel Inherent Component of the Nuclear Basket, Resident in a State of Reciprocal Dependence with TPR. , Gunkel P., Cells. July 30, 2021; 10 (8):
Axon terminals control endolysosome diffusion to support synaptic remodelling. , Terni B., Life Sci Alliance. July 5, 2021; 4 (8):
DLG5 variants are associated with multiple congenital anomalies including ciliopathy phenotypes. , Marquez J ., J Med Genet. July 1, 2021; 58 (7): 453-464.
Ciliogenesis and autophagy are coordinately regulated by EphA2 in the cornea to maintain proper epithelial architecture. , Kaplan N., Ocul Surf. July 1, 2021; 21 193-205.