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Distinctive mechanisms of epilepsy-causing mutants discovered by measuring S4 movement in KCNQ2 channels. , Edmond MA., Elife. June 1, 2022; 11
Familial neonatal seizures caused by the Kv7.3 selectivity filter mutation T313I. , Maghera J., Epilepsia Open. December 1, 2020; 5 (4): 562-573.
Epilepsy-associated mutations in the voltage sensor of KCNQ3 affect voltage dependence of channel opening. , Barro-Soria R., J Gen Physiol. February 4, 2019; 151 (2): 247-257.
In silico re-engineering of a neurotransmitter to activate KCNQ potassium channels in an isoform-specific manner. , Manville RW., Commun Biol. January 1, 2019; 2 401.
Deconstruction of an African folk medicine uncovers a novel molecular strategy for therapeutic potassium channel activation. , De Silva AM., Sci Adv. November 14, 2018; 4 (11): eaav0824.
One drug-sensitive subunit is sufficient for a near-maximal retigabine effect in KCNQ channels. , Yau MC., J Gen Physiol. October 1, 2018; 150 (10): 1421-1431.
Ancient and modern anticonvulsants act synergistically in a KCNQ potassium channel binding pocket. , Manville RW., Nat Commun. September 21, 2018; 9 (1): 3845.
Direct neurotransmitter activation of voltage-gated potassium channels. , Manville RW., Nat Commun. May 10, 2018; 9 (1): 1847.
Atomic basis for therapeutic activation of neuronal potassium channels. , Kim RY., Nat Commun. September 3, 2015; 6 8116.
Impaired ion channel function related to a common KCNQ1 mutation - implications for risk stratification in long QT syndrome 1. , Aidery P., Gene. December 10, 2012; 511 (1): 26-33.
Surface expression and subunit specific control of steady protein levels by the Kv7.2 helix A-B linker. , Aivar P., PLoS One. January 1, 2012; 7 (10): e47263.
The acrylamide (S)-2 as a positive and negative modulator of Kv7 channels expressed in Xenopus laevis oocytes. , Blom SM., PLoS One. December 11, 2009; 4 (12): e8251.
Second coiled-coil domain of KCNQ channel controls current expression and subfamily specific heteromultimerization by salt bridge networks. , Nakajo K., J Physiol. June 15, 2008; 586 (12): 2827-40.
Inhibitory effects of pimozide on cloned and native voltage-gated potassium channels. , Zhang ZH ., Brain Res Mol Brain Res. July 4, 2003; 115 (1): 29-38.