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Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR. , Sempou E., Nat Commun. November 5, 2022; 13 (1): 6681.
Lysosomes are required for early dorsal signaling in the Xenopus embryo. , Tejeda-Muñoz N., Proc Natl Acad Sci U S A. April 26, 2022; 119 (17): e2201008119.
Kindlin2 regulates neural crest specification via integrin-independent regulation of the FGF signaling pathway. , Wang H., Development. May 15, 2021; 148 (10):
Chromatin accessibility and histone acetylation in the regulation of competence in early development. , Esmaeili M., Dev Biol. June 1, 2020; 462 (1): 20-35.
The secreted BMP antagonist ERFE is required for the development of a functional circulatory system in Xenopus. , Melchert J., Dev Biol. March 15, 2020; 459 (2): 138-148.
Head formation requires Dishevelled degradation that is mediated by March2 in concert with Dapper1. , Lee H , Lee H ., Development. April 10, 2018; 145 (7):
Candidate Heterotaxy Gene FGFR4 Is Essential for Patterning of the Left- Right Organizer in Xenopus. , Sempou E., Front Physiol. January 1, 2018; 9 1705.
Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. , Kirsch N., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.
The RNF146 E3 ubiquitin ligase is required for the control of Wnt signaling and body pattern formation in Xenopus. , Zhu X., Mech Dev. October 1, 2017; 147 28-36.
The phosphatase Pgam5 antagonizes Wnt/ β-Catenin signaling in embryonic anterior- posterior axis patterning. , Rauschenberger V., Development. June 15, 2017; 144 (12): 2234-2247.
Brg1 chromatin remodeling ATPase balances germ layer patterning by amplifying the transcriptional burst at midblastula transition. , Wagner G., PLoS Genet. May 12, 2017; 13 (5): e1006757.
Cholesterol-rich membrane microdomains modulate Wnt/ β-catenin morphogen gradient during Xenopus development. , Reis AH., Mech Dev. November 1, 2016; 142 30-39.
Measuring Absolute RNA Copy Numbers at High Temporal Resolution Reveals Transcriptome Kinetics in Development. , Owens ND., Cell Rep. January 26, 2016; 14 (3): 632-47.
NF2/ Merlin is required for the axial pattern formation in the Xenopus laevis embryo. , Zhu X., Mech Dev. November 1, 2015; 138 Pt 3 305-12.
The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation. , Acosta H., Development. March 15, 2015; 142 (6): 1146-58.
Fezf2 promotes neuronal differentiation through localised activation of Wnt/ β-catenin signalling during forebrain development. , Zhang S ., Development. December 1, 2014; 141 (24): 4794-805.
NEDD4L regulates convergent extension movements in Xenopus embryos via Disheveled-mediated non-canonical Wnt signaling. , Zhang Y ., Dev Biol. August 1, 2014; 392 (1): 15-25.
Maternal Dead-End1 is required for vegetal cortical microtubule assembly during Xenopus axis specification. , Mei W., Development. June 1, 2013; 140 (11): 2334-44.
Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis. , Colas AR., Genes Dev. December 1, 2012; 26 (23): 2567-79.
Serotonin signaling is required for Wnt-dependent GRP specification and leftward flow in Xenopus. , Beyer T., Curr Biol. January 10, 2012; 22 (1): 33-9.
Maternal xNorrin, a canonical Wnt signaling agonist and TGF-β antagonist, controls early neuroectoderm specification in Xenopus. , Xu S., PLoS Biol. January 1, 2012; 10 (3): e1001286.
Maternal Wnt/ β-catenin signaling coactivates transcription through NF-κB binding sites during Xenopus axis formation. , Armstrong NJ., PLoS One. January 1, 2012; 7 (5): e36136.
Notch destabilises maternal beta-catenin and restricts dorsal- anterior development in Xenopus. , Acosta H., Development. June 1, 2011; 138 (12): 2567-79.
Wnt/beta-catenin signaling is involved in the induction and maintenance of primitive hematopoiesis in the vertebrate embryo. , Tran HT., Proc Natl Acad Sci U S A. September 14, 2010; 107 (37): 16160-5.
beta-Catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2. , Blythe SA ., Dev Cell. August 17, 2010; 19 (2): 220-31.
Early activation of FGF and nodal pathways mediates cardiac specification independently of Wnt/beta-catenin signaling. , Samuel LJ., PLoS One. October 28, 2009; 4 (10): e7650.
Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1. , Louie SH., PLoS One. January 1, 2009; 4 (2): e4310.
Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways. , Zhao H ., Development. April 1, 2008; 135 (7): 1283-93.
Beta- arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo. , Bryja V ., Proc Natl Acad Sci U S A. April 17, 2007; 104 (16): 6690-5.
Shisa2 promotes the maturation of somitic precursors and transition to the segmental fate in Xenopus embryos. , Nagano T., Development. December 1, 2006; 133 (23): 4643-54.
Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides. , Rana AA., PLoS Genet. November 17, 2006; 2 (11): e193.
NARF, an nemo-like kinase ( NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF). , Yamada M., J Biol Chem. July 28, 2006; 281 (30): 20749-20760.
Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/beta-catenin signaling. , Swain RK., Cell Commun Signal. October 19, 2005; 3 12.
New roles for FoxH1 in patterning the early embryo. , Kofron M ., Development. October 1, 2004; 131 (20): 5065-78.
XSENP1, a novel sumo-specific protease in Xenopus, inhibits normal head formation by down-regulation of Wnt/beta-catenin signalling. , Yukita A., Genes Cells. August 1, 2004; 9 (8): 723-36.
PP2A:B56epsilon is required for Wnt/beta-catenin signaling during embryonic development. , Yang J ., Development. December 1, 2003; 130 (23): 5569-78.
Xhex-expressing endodermal tissues are essential for anterior patterning in Xenopus. , Smithers LE ., Mech Dev. December 1, 2002; 119 (2): 191-200.
FGF signaling restricts the primary blood islands to ventral mesoderm. , Kumano G ., Dev Biol. December 15, 2000; 228 (2): 304-14.
The maternal Xenopus beta-catenin signaling pathway, activated by frizzled homologs, induces goosecoid in a cell non-autonomous manner. , Brown JD., Dev Growth Differ. August 1, 2000; 42 (4): 347-57.
Antagonist activity of DWnt-4 and wingless in the Drosophila embryonic ventral ectoderm and in heterologous Xenopus assays. , Gieseler K ., Mech Dev. July 1, 1999; 85 (1-2): 123-31.
XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development. , Brannon M., Development. June 1, 1999; 126 (14): 3159-70.
Frizzled-8 is expressed in the Spemann organizer and plays a role in early morphogenesis. , Deardorff MA., Development. July 1, 1998; 125 (14): 2687-700.
Mutant Vg1 ligands disrupt endoderm and mesoderm formation in Xenopus embryos. , Joseph EM ., Development. July 1, 1998; 125 (14): 2677-85.
The Xenopus Emx genes identify presumptive dorsal telencephalon and are induced by head organizer signals. , Pannese M., Mech Dev. April 1, 1998; 73 (1): 73-83.
Animal and vegetal pole cells of early Xenopus embryos respond differently to maternal dorsal determinants: implications for the patterning of the organiser. , Darras S., Development. November 1, 1997; 124 (21): 4275-86.