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Progesterone induces meiosis through two obligate co-receptors with PLA2 activity. , Nader N, Assaf L, Zarif L, Halama A, Yadav S, Dib M, Attarwala N, Chen Q, Suhre K, Gross S, Machaca K ., Elife. January 28, 2025; 13
The carboxy terminal coiled-coil modulates Orai1 internalization during meiosis. , Hodeify R, Dib M, Alcantara-Adap E, Courjaret R, Nader N, Reyes CZ, Hammad AS, Hubrack S, Yu F, Machaca K ., Sci Rep. January 27, 2021; 11 (1): 2290.
Membrane progesterone receptor induces meiosis in Xenopus oocytes through endocytosis into signaling endosomes and interaction with APPL1 and Akt2. , Nader N, Dib M, Hodeify R, Courjaret R, Elmi A, Hammad AS, Dey R, Huang XY , Machaca K ., PLoS Biol. November 2, 2020; 18 (11): e3000901.
The VLDL receptor regulates membrane progesterone receptor trafficking and non-genomic signaling. , Nader N, Dib M, Courjaret R, Hodeify R, Machaca R, Graumann J, Machaca K ., J Cell Sci. May 23, 2018; 131 (10):
Transition metal dependent regulation of the signal transduction cascade driving oocyte meiosis. , Schaefer-Ramadan S, Hubrack S, Machaca K ., J Cell Physiol. April 1, 2018; 233 (4): 3164-3175.
Ion Channel Function During Oocyte Maturation and Fertilization. , Carvacho I, Piesche M, Maier TJ, Machaca K ., Front Cell Dev Biol. January 1, 2018; 6 63.
Store-Operated Ca2+ Entry in Oocytes Modulate the Dynamics of IP3 -Dependent Ca2+ Release From Oscillatory to Tonic. , Courjaret R, Dib M, Machaca K ., J Cell Physiol. May 1, 2017; 232 (5): 1095-1103.
The Ca2+-activated Cl- channel Ano1 controls microvilli length and membrane surface area in the oocyte. , Courjaret R, Hodeify R, Hubrack S, Ibrahim A, Dib M, Daas S, Machaca K ., J Cell Sci. July 1, 2016; 129 (13): 2548-58.
Xenopus Oocyte As a Model System to Study Store-Operated Ca(2+) Entry (SOCE). , Courjaret R, Machaca K ., Front Cell Dev Biol. June 24, 2016; 4 66.
Release from Xenopus oocyte prophase I meiotic arrest is independent of a decrease in cAMP levels or PKA activity. , Nader N, Courjaret R, Dib M, Kulkarni RP, Machaca K ., Development. June 1, 2016; 143 (11): 1926-36.
A novel approach to the expression and purification of recombinant Xenopus Cdc25C. , Schaefer-Ramadan S, Bendriss G, Hubrack S, Al-Abdulmalek A, Machaca K ., Protein Expr Purif. April 1, 2016; 120 148-52.
The Role of Flexible Loops in Folding, Trafficking and Activity of Equilibrative Nucleoside Transporters. , Aseervatham J, Tran L, Machaca K , Boudker O., PLoS One. September 1, 2015; 10 (9): e0136779.
Role for endocytosis of a constitutively active GPCR (GPR185) in releasing vertebrate oocyte meiotic arrest. , Nader N, Dib M, Daalis A, Kulkarni RP, Machaca K ., Dev Biol. November 15, 2014; 395 (2): 355-66.
The role of IP3 receptor channel clustering in Ca2+ wave propagation during oocyte maturation. , Ullah A, Jung P, Ullah G, Machaca K ., Prog Mol Biol Transl Sci. January 1, 2014; 123 83-101.
Mid-range Ca2+ signalling mediated by functional coupling between store-operated Ca2+ entry and IP3-dependent Ca2+ release. , Courjaret R, Machaca K ., Nat Commun. January 1, 2014; 5 3916.
The Xenopus TRPV6 homolog encodes a Mg(2+) -permeant channel that is inhibited by interaction with TRPC1. , Courjaret R, Hubrack S, Daalis A, Dib M, Machaca K ., J Cell Physiol. December 1, 2013; 228 (12): 2386-98.
Downregulation of store-operated Ca2+ entry during mammalian meiosis is required for the egg-to- embryo transition. , Lee B, Palermo G, Machaca K ., J Cell Sci. April 1, 2013; 126 (Pt 7): 1672-81.
How to make a good egg!: The need for remodeling of oocyte Ca(2+) signaling to mediate the egg-to- embryo transition. , Nader N, Kulkarni RP, Dib M, Machaca K ., Cell Calcium. January 1, 2013; 53 (1): 41-54.
Phosphorylation of the rat Ins(1,4,5)P₃ receptor at T930 within the coupling domain decreases its affinity to Ins(1,4,5)P₃. , Haun S, Sun L, Hubrack S, Yule D, Machaca K ., Channels (Austin). January 1, 2012; 6 (5): 379-84.
Role of the STIM1 C-terminal domain in STIM1 clustering. , Yu F, Sun L, Courjaret R, Machaca K ., J Biol Chem. March 11, 2011; 286 (10): 8375-8384.
Endoplasmic reticulum remodeling tunes IP₃-dependent Ca²+ release sensitivity. , Sun L, Yu F, Ullah A, Hubrack S, Daalis A, Jung P, Machaca K ., PLoS One. January 1, 2011; 6 (11): e27928.
Constitutive recycling of the store-operated Ca2+ channel Orai1 and its internalization during meiosis. , Yu F, Sun L, Machaca K ., J Cell Biol. November 1, 2010; 191 (3): 523-35.
Orai1 internalization and STIM1 clustering inhibition modulate SOCE inactivation during meiosis. , Yu F, Sun L, Machaca K ., Proc Natl Acad Sci U S A. October 13, 2009; 106 (41): 17401-6.
Kinase-dependent regulation of inositol 1,4,5-trisphosphate-dependent Ca2+ release during oocyte maturation. , Sun L, Haun S, Jones RC, Edmondson RD, Machaca K ., J Biol Chem. July 24, 2009; 284 (30): 20184-96.
Internalization of plasma membrane Ca2+-ATPase during Xenopus oocyte maturation. , El-Jouni W, Haun S, Machaca K ., Dev Biol. December 1, 2008; 324 (1): 99-107.
Ca2+ homeostasis regulates Xenopus oocyte maturation. , Sun L, Hodeify R, Haun S, Charlesworth A , MacNicol AM , Ponnappan S, Ponnappan U, Prigent C , Machaca K ., Biol Reprod. April 1, 2008; 78 (4): 726-35.
Modeling Ca2+ signaling differentiation during oocyte maturation. , Ullah G, Jung P, Machaca K ., Cell Calcium. December 1, 2007; 42 (6): 556-64.
Zinc regulates the ability of Cdc25C to activate MPF/ cdk1. , Sun L, Chai Y, Hannigan R, Bhogaraju VK, Machaca K ., J Cell Physiol. October 1, 2007; 213 (1): 98-104.
Vesicular traffic at the cell membrane regulates oocyte meiotic arrest. , El-Jouni W, Haun S, Hodeify R, Hosein Walker A, Machaca K ., Development. September 1, 2007; 134 (18): 3307-15.
Calcium signaling differentiation during Xenopus oocyte maturation. , El-Jouni W, Jang B, Haun S, Machaca K ., Dev Biol. December 15, 2005; 288 (2): 514-25.
Increased sensitivity and clustering of elementary Ca2+ release events during oocyte maturation. , Machaca K ., Dev Biol. November 1, 2004; 275 (1): 170-82.
Ca(2+)(cyt) negatively regulates the initiation of oocyte maturation. , Sun L, Machaca K ., J Cell Biol. April 1, 2004; 165 (1): 63-75.
Ca2+-calmodulin-dependent protein kinase II potentiates store-operated Ca2+ current. , Machaca K ., J Biol Chem. September 5, 2003; 278 (36): 33730-7.
Induction of maturation-promoting factor during Xenopus oocyte maturation uncouples Ca(2+) store depletion from store-operated Ca(2+) entry. , Machaca K , Haun S., J Cell Biol. January 7, 2002; 156 (1): 75-85.
Store-operated calcium entry inactivates at the germinal vesicle breakdown stage of Xenopus meiosis. , Machaca K , Haun S., J Biol Chem. December 8, 2000; 275 (49): 38710-5.
Adenophostin A and inositol 1,4,5-trisphosphate differentially activate Cl- currents in Xenopus oocytes because of disparate Ca2+ release kinetics. , Machaca K , Hartzell HC., J Biol Chem. February 19, 1999; 274 (8): 4824-31.
Reversible Ca gradients between the subplasmalemma and cytosol differentially activate Ca-dependent Cl currents. , Machaca K , HC Hartzell., J Gen Physiol. February 1, 1999; 113 (2): 249-66.
Asymmetrical distribution of Ca-activated Cl channels in Xenopus oocytes. , Machaca K , Hartzell HC., Biophys J. March 1, 1998; 74 (3): 1286-95.
Effects of adenophostin-A and inositol-1,4,5-trisphosphate on Cl- currents in Xenopus laevis oocytes. , Hartzell HC, Machaca K , Hirayama Y., Mol Pharmacol. April 1, 1997; 51 (4): 683-92.