Harv V Isaacs - Publications

Publications (42)

XB-PERS-582

Publications By Harv V Isaacs

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Regulation of gene expression downstream of a novel Fgf/Erk pathway during Xenopus development., Cowell LM, King M, West H, Broadsmith M, Genever P, Pownall ME, Isaacs HV., PLoS One. January 1, 2023; 18 (10): e0286040.
A comparative analysis of fibroblast growth factor receptor signalling during Xenopus development., Brunsdon H, Isaacs HV., Biol Cell. May 1, 2020; 112 (5): 127-139.
Xenopus laevis FGF16 activates the expression of genes coding for the transcription factors Sp5 and Sp5l., Elsy M, Rowbotham A, Lord H, Isaacs HV, Pownall ME., Int J Dev Biol. January 1, 2019; 63 (11-12): 631-639.
N1-Src Kinase Is Required for Primary Neurogenesis in Xenopus tropicalis., Lewis PA, Bradley IC, Pizzey AR, Isaacs HV, Evans GJO., J Neurosci. August 30, 2017; 37 (35): 8477-8485.
lin28 proteins promote expression of 17∼92 family miRNAs during amphibian development., Warrander F, Faas L, Kovalevskiy O, Peters D, Coles M, Antson AA, Genever P, Isaacs HV., Dev Dyn. January 1, 2016; 245 (1): 34-46.
Cdx ParaHox genes acquired distinct developmental roles after gene duplication in vertebrate evolution., Marlétaz F, Maeso I, Faas L, Isaacs HV, Holland PW., BMC Biol. August 1, 2015; 13 56.
An essential role for LPA signalling in telencephalon development., Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L., Development. February 1, 2014; 141 (4): 940-9.
Lin28 proteins are required for germ layer specification in Xenopus., Faas L, Warrander FC, Maguire R, Ramsbottom SA, Quinn D, Genever P, Isaacs HV., Development. March 1, 2013; 140 (5): 976-86.
Early transcriptional targets of MyoD link myogenesis and somitogenesis., Maguire RJ, Isaacs HV, Pownall ME., Dev Biol. November 15, 2012; 371 (2): 256-68.
Gsx transcription factors repress Iroquois gene expression., Winterbottom EF, Ramsbottom SA, Isaacs HV., Dev Dyn. June 1, 2011; 240 (6): 1422-9.
Conserved and novel roles for the Gsh2 transcription factor in primary neurogenesis., Winterbottom EF, Illes JC, Faas L, Isaacs HV., Development. August 1, 2010; 137 (16): 2623-31.
FGF signalling modulates transcriptional repression by Xenopus groucho-related-4., Burks PJ, Isaacs HV, Pownall ME., Biol Cell. May 1, 2009; 101 (5): 301-8.
Overlapping functions of Cdx1, Cdx2, and Cdx4 in the development of the amphibian Xenopus tropicalis., Faas L, Isaacs HV., Dev Dyn. April 1, 2009; 238 (4): 835-52.
Cloning and expression analysis of the anterior parahox genes, Gsh1 and Gsh2 from Xenopus tropicalis., Illes JC, Winterbottom E, Isaacs HV., Dev Dyn. January 1, 2009; 238 (1): 194-203.
Characterisation of the fibroblast growth factor dependent transcriptome in early development., Branney PA, Faas L, Steane SE, Pownall ME, Isaacs HV., PLoS One. January 1, 2009; 4 (3): e4951.
Expression of enzymes involved in thyroid hormone metabolism during the early development of Xenopus tropicalis., Tindall AJ, Morris ID, Pownall ME, Isaacs HV., Biol Cell. March 1, 2007; 99 (3): 151-63.
FGF4 regulates blood and muscle specification in Xenopus laevis., Isaacs HV, Deconinck AE, Pownall ME., Biol Cell. March 1, 2007; 99 (3): 165-73.
FGF signal transduction and the regulation of Cdx gene expression., Keenan ID, Sharrard RM, Isaacs HV., Dev Biol. November 15, 2006; 299 (2): 478-88.
A consensus Oct1 binding site is required for the activity of the Xenopus Cdx4 promoter., Reece-Hoyes JS, Keenan ID, Pownall ME, Isaacs HV., Dev Biol. June 15, 2005; 282 (2): 509-23.
Xenopus tropicalis peroxidasin gene is expressed within the developing neural tube and pronephric kidney., Tindall AJ, Pownall ME, Morris ID, Isaacs HV., Dev Dyn. February 1, 2005; 232 (2): 377-84.
A novel role for a nodal-related protein; Xnr3 regulates convergent extension movements via the FGF receptor., Yokota C, Kofron M, Zuck M, Houston DW, Isaacs H, Asashima M, Wylie CC, Heasman J., Development. May 1, 2003; 130 (10): 2199-212.
An inducible system for the study of FGF signalling in early amphibian development., Pownall ME, Welm BE, Freeman KW, Spencer DM, Rosen JM, Isaacs HV., Dev Biol. April 1, 2003; 256 (1): 89-99.
eFGF is required for activation of XmyoD expression in the myogenic cell lineage of Xenopus laevis., Fisher ME, Isaacs HV, Pownall ME., Development. March 1, 2002; 129 (6): 1307-15.
Cloning and expression of the Cdx family from the frog Xenopus tropicalis., Reece-Hoyes JS, Keenan ID, Isaacs HV., Dev Dyn. January 1, 2002; 223 (1): 134-40.
Anteroposterior patterning by mutual repression of orthodenticle and caudal-type transcription factors., Isaacs HV, Andreazzoli M, Slack JM., Evol Dev. January 1, 1999; 1 (3): 143-52.
Expression and functions of FGF-3 in Xenopus development., Lombardo A, Isaacs HV, Slack JM., Int J Dev Biol. November 1, 1998; 42 (8): 1101-7.
Regulation of Hox gene expression and posterior development by the Xenopus caudal homologue Xcad3., Isaacs HV, Pownall ME, Slack JM., EMBO J. June 15, 1998; 17 (12): 3413-27.
Two phases of Hox gene regulation during early Xenopus development., Pownall ME, Isaacs HV, Slack JM., Curr Biol. May 21, 1998; 8 (11): 673-6.
New perspectives on the role of the fibroblast growth factor family in amphibian development., Isaacs HV., Cell Mol Life Sci. April 1, 1997; 53 (4): 350-61.
eFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus., Pownall ME, Tucker AS, Slack JM, Isaacs HV., Development. December 1, 1996; 122 (12): 3881-92.
eFGF is expressed in the dorsal midline of Xenopus laevis., Isaacs HV, Pownall ME, Slack JM., Int J Dev Biol. August 1, 1995; 39 (4): 575-9.
eFGF regulates Xbra expression during Xenopus gastrulation., Isaacs HV, Pownall ME, Slack JM., EMBO J. October 3, 1994; 13 (19): 4469-81.
The role of fibroblast growth factors in early Xenopus development., Slack JM, Isaacs HV., Biochem Soc Trans. August 1, 1994; 22 (3): 585-9.
The Einsteck-method: position and structure of projections formed by implants of a ventral character., Slack JM, Isaacs HV., Dev Biol. January 1, 1994; 161 (1): 313-7.
Developmental expression of the Xenopus int-2 (FGF-3) gene: activation by mesodermal and neural induction., Tannahill D, Isaacs HV, Close MJ, Peters G, Slack JM., Development. July 1, 1992; 115 (3): 695-702.
Expression of a novel FGF in the Xenopus embryo. A new candidate inducing factor for mesoderm formation and anteroposterior specification., Isaacs HV, Tannahill D, Slack JM., Development. March 1, 1992; 114 (3): 711-20.
Specification of the body plan during Xenopus gastrulation: dorsoventral and anteroposterior patterning of the mesoderm., Slack JM, Isaacs HV, Johnson GE, Lettice LA, Tannahill D, Thompson J., Dev Suppl. January 1, 1992; 143-9.
A mesoderm-inducing factor produced by WEHI-3 murine myelomonocytic leukemia cells is activin A., Albano RM, Godsave SF, Huylebroeck D, Van Nimmen K, Isaacs HV, Slack JM, Smith JC., Development. October 1, 1990; 110 (2): 435-43.
Mesoderm induction by fibroblast growth factor in early Xenopus development., Slack JM, Darlington BG, Gillespie LL, Godsave SF, Isaacs HV, Paterno GD., Philos Trans R Soc Lond B Biol Sci. March 12, 1990; 327 (1239): 75-84.
The role of fibroblast growth factor in early Xenopus development., Slack JM, Darlington BG, Gillespie LL, Godsave SF, Isaacs HV, Paterno GD., Development. January 1, 1989; 107 Suppl 141-8.
Inductive effects of fibroblast growth factor and lithium ion on Xenopus blastula ectoderm., Slack JM, Isaacs HV, Darlington BG., Development. July 1, 1988; 103 (3): 581-90.
Mesoderm-inducing factors: a small class of molecules., Godsave SF, Isaacs HV, Slack JM., Development. March 1, 1988; 102 (3): 555-66.

Regulation of gene expression downstream of a novel Fgf/Erk pathway during Xenopus development., Cowell LM, King M, West H, Broadsmith M, Genever P, Pownall ME, Isaacs HV., PLoS One. January 1, 2023; 18 (10): e0286040.

A comparative analysis of fibroblast growth factor receptor signalling during Xenopus development., Brunsdon H, Isaacs HV., Biol Cell. May 1, 2020; 112 (5): 127-139.

Xenopus laevis FGF16 activates the expression of genes coding for the transcription factors Sp5 and Sp5l., Elsy M, Rowbotham A, Lord H, Isaacs HV, Pownall ME., Int J Dev Biol. January 1, 2019; 63 (11-12): 631-639.

N1-Src Kinase Is Required for Primary Neurogenesis in Xenopus tropicalis., Lewis PA, Bradley IC, Pizzey AR, Isaacs HV, Evans GJO., J Neurosci. August 30, 2017; 37 (35): 8477-8485.

lin28 proteins promote expression of 17∼92 family miRNAs during amphibian development., Warrander F, Faas L, Kovalevskiy O, Peters D, Coles M, Antson AA, Genever P, Isaacs HV., Dev Dyn. January 1, 2016; 245 (1): 34-46.

Cdx ParaHox genes acquired distinct developmental roles after gene duplication in vertebrate evolution., Marlétaz F, Maeso I, Faas L, Isaacs HV, Holland PW., BMC Biol. August 1, 2015; 13 56.

An essential role for LPA signalling in telencephalon development., Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L., Development. February 1, 2014; 141 (4): 940-9.

Lin28 proteins are required for germ layer specification in Xenopus., Faas L, Warrander FC, Maguire R, Ramsbottom SA, Quinn D, Genever P, Isaacs HV., Development. March 1, 2013; 140 (5): 976-86.

Early transcriptional targets of MyoD link myogenesis and somitogenesis., Maguire RJ, Isaacs HV, Pownall ME., Dev Biol. November 15, 2012; 371 (2): 256-68.

Gsx transcription factors repress Iroquois gene expression., Winterbottom EF, Ramsbottom SA, Isaacs HV., Dev Dyn. June 1, 2011; 240 (6): 1422-9.

Conserved and novel roles for the Gsh2 transcription factor in primary neurogenesis., Winterbottom EF, Illes JC, Faas L, Isaacs HV., Development. August 1, 2010; 137 (16): 2623-31.

FGF signalling modulates transcriptional repression by Xenopus groucho-related-4., Burks PJ, Isaacs HV, Pownall ME., Biol Cell. May 1, 2009; 101 (5): 301-8.

Overlapping functions of Cdx1, Cdx2, and Cdx4 in the development of the amphibian Xenopus tropicalis., Faas L, Isaacs HV., Dev Dyn. April 1, 2009; 238 (4): 835-52.

Cloning and expression analysis of the anterior parahox genes, Gsh1 and Gsh2 from Xenopus tropicalis., Illes JC, Winterbottom E, Isaacs HV., Dev Dyn. January 1, 2009; 238 (1): 194-203.

Characterisation of the fibroblast growth factor dependent transcriptome in early development., Branney PA, Faas L, Steane SE, Pownall ME, Isaacs HV., PLoS One. January 1, 2009; 4 (3): e4951.

Expression of enzymes involved in thyroid hormone metabolism during the early development of Xenopus tropicalis., Tindall AJ, Morris ID, Pownall ME, Isaacs HV., Biol Cell. March 1, 2007; 99 (3): 151-63.

FGF4 regulates blood and muscle specification in Xenopus laevis., Isaacs HV, Deconinck AE, Pownall ME., Biol Cell. March 1, 2007; 99 (3): 165-73.

FGF signal transduction and the regulation of Cdx gene expression., Keenan ID, Sharrard RM, Isaacs HV., Dev Biol. November 15, 2006; 299 (2): 478-88.

A consensus Oct1 binding site is required for the activity of the Xenopus Cdx4 promoter., Reece-Hoyes JS, Keenan ID, Pownall ME, Isaacs HV., Dev Biol. June 15, 2005; 282 (2): 509-23.

Xenopus tropicalis peroxidasin gene is expressed within the developing neural tube and pronephric kidney., Tindall AJ, Pownall ME, Morris ID, Isaacs HV., Dev Dyn. February 1, 2005; 232 (2): 377-84.

A novel role for a nodal-related protein; Xnr3 regulates convergent extension movements via the FGF receptor., Yokota C, Kofron M, Zuck M, Houston DW, Isaacs H, Asashima M, Wylie CC, Heasman J., Development. May 1, 2003; 130 (10): 2199-212.

An inducible system for the study of FGF signalling in early amphibian development., Pownall ME, Welm BE, Freeman KW, Spencer DM, Rosen JM, Isaacs HV., Dev Biol. April 1, 2003; 256 (1): 89-99.

eFGF is required for activation of XmyoD expression in the myogenic cell lineage of Xenopus laevis., Fisher ME, Isaacs HV, Pownall ME., Development. March 1, 2002; 129 (6): 1307-15.

Cloning and expression of the Cdx family from the frog Xenopus tropicalis., Reece-Hoyes JS, Keenan ID, Isaacs HV., Dev Dyn. January 1, 2002; 223 (1): 134-40.

Anteroposterior patterning by mutual repression of orthodenticle and caudal-type transcription factors., Isaacs HV, Andreazzoli M, Slack JM., Evol Dev. January 1, 1999; 1 (3): 143-52.

Expression and functions of FGF-3 in Xenopus development., Lombardo A, Isaacs HV, Slack JM., Int J Dev Biol. November 1, 1998; 42 (8): 1101-7.

Regulation of Hox gene expression and posterior development by the Xenopus caudal homologue Xcad3., Isaacs HV, Pownall ME, Slack JM., EMBO J. June 15, 1998; 17 (12): 3413-27.

Two phases of Hox gene regulation during early Xenopus development., Pownall ME, Isaacs HV, Slack JM., Curr Biol. May 21, 1998; 8 (11): 673-6.

New perspectives on the role of the fibroblast growth factor family in amphibian development., Isaacs HV., Cell Mol Life Sci. April 1, 1997; 53 (4): 350-61.

eFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus., Pownall ME, Tucker AS, Slack JM, Isaacs HV., Development. December 1, 1996; 122 (12): 3881-92.

eFGF is expressed in the dorsal midline of Xenopus laevis., Isaacs HV, Pownall ME, Slack JM., Int J Dev Biol. August 1, 1995; 39 (4): 575-9.

eFGF regulates Xbra expression during Xenopus gastrulation., Isaacs HV, Pownall ME, Slack JM., EMBO J. October 3, 1994; 13 (19): 4469-81.

The role of fibroblast growth factors in early Xenopus development., Slack JM, Isaacs HV., Biochem Soc Trans. August 1, 1994; 22 (3): 585-9.

The Einsteck-method: position and structure of projections formed by implants of a ventral character., Slack JM, Isaacs HV., Dev Biol. January 1, 1994; 161 (1): 313-7.

Developmental expression of the Xenopus int-2 (FGF-3) gene: activation by mesodermal and neural induction., Tannahill D, Isaacs HV, Close MJ, Peters G, Slack JM., Development. July 1, 1992; 115 (3): 695-702.

Expression of a novel FGF in the Xenopus embryo. A new candidate inducing factor for mesoderm formation and anteroposterior specification., Isaacs HV, Tannahill D, Slack JM., Development. March 1, 1992; 114 (3): 711-20.

Specification of the body plan during Xenopus gastrulation: dorsoventral and anteroposterior patterning of the mesoderm., Slack JM, Isaacs HV, Johnson GE, Lettice LA, Tannahill D, Thompson J., Dev Suppl. January 1, 1992; 143-9.

A mesoderm-inducing factor produced by WEHI-3 murine myelomonocytic leukemia cells is activin A., Albano RM, Godsave SF, Huylebroeck D, Van Nimmen K, Isaacs HV, Slack JM, Smith JC., Development. October 1, 1990; 110 (2): 435-43.

Mesoderm induction by fibroblast growth factor in early Xenopus development., Slack JM, Darlington BG, Gillespie LL, Godsave SF, Isaacs HV, Paterno GD., Philos Trans R Soc Lond B Biol Sci. March 12, 1990; 327 (1239): 75-84.

The role of fibroblast growth factor in early Xenopus development., Slack JM, Darlington BG, Gillespie LL, Godsave SF, Isaacs HV, Paterno GD., Development. January 1, 1989; 107 Suppl 141-8.

Inductive effects of fibroblast growth factor and lithium ion on Xenopus blastula ectoderm., Slack JM, Isaacs HV, Darlington BG., Development. July 1, 1988; 103 (3): 581-90.

Mesoderm-inducing factors: a small class of molecules., Godsave SF, Isaacs HV, Slack JM., Development. March 1, 1988; 102 (3): 555-66.

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