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Profile Publications (45)

Publications By Harry V. Isaacs

Results 1 - 45 of 45 results

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Regulation of gene expression downstream of a novel Fgf/Erk pathway during Xenopus development., Cowell LM, King M, West H, Broadsmith M, Genever P, Pownall ME, Isaacs HV., PLoS One. January 1, 2023; 18 (10): e0286040.                                  

A comparative analysis of fibroblast growth factor receptor signalling during Xenopus development., Brunsdon H, Isaacs HV., Biol Cell. May 1, 2020; 112 (5): 127-139.                

Xenopus laevis FGF16 activates the expression of genes coding for the transcription factors Sp5 and Sp5l., Elsy M, Rowbotham A, Lord H, Isaacs HV, Pownall ME., Int J Dev Biol. January 1, 2019; 63 (11-12): 631-639.            

N1-Src Kinase Is Required for Primary Neurogenesis in Xenopus tropicalis., Lewis PA, Bradley IC, Pizzey AR, Isaacs HV, Evans GJO., J Neurosci. August 30, 2017; 37 (35): 8477-8485.          

lin28 proteins promote expression of 17∼92 family miRNAs during amphibian development., Warrander F, Faas L, Kovalevskiy O, Peters D, Coles M, Antson AA, Genever P, Isaacs HV., Dev Dyn. January 1, 2016; 245 (1): 34-46.            

Cdx ParaHox genes acquired distinct developmental roles after gene duplication in vertebrate evolution., Marlétaz F, Maeso I, Faas L, Isaacs HV, Holland PW., BMC Biol. August 1, 2015; 13 56.          

An essential role for LPA signalling in telencephalon development., Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L., Development. February 1, 2014; 141 (4): 940-9.                            

Lin28 proteins are required for germ layer specification in Xenopus., Faas L, Warrander FC, Maguire R, Ramsbottom SA, Quinn D, Genever P, Isaacs HV., Development. March 1, 2013; 140 (5): 976-86.                      

Early transcriptional targets of MyoD link myogenesis and somitogenesis., Maguire RJ, Isaacs HV, Pownall ME., Dev Biol. November 15, 2012; 371 (2): 256-68.                                                    

Gsx transcription factors repress Iroquois gene expression., Winterbottom EF, Ramsbottom SA, Isaacs HV., Dev Dyn. June 1, 2011; 240 (6): 1422-9.        

Conserved and novel roles for the Gsh2 transcription factor in primary neurogenesis., Winterbottom EF, Illes JC, Faas L, Isaacs HV., Development. August 1, 2010; 137 (16): 2623-31.        

FGF signalling modulates transcriptional repression by Xenopus groucho-related-4., Burks PJ, Isaacs HV, Pownall ME., Biol Cell. May 1, 2009; 101 (5): 301-8.

Overlapping functions of Cdx1, Cdx2, and Cdx4 in the development of the amphibian Xenopus tropicalis., Faas L, Isaacs HV., Dev Dyn. April 1, 2009; 238 (4): 835-52.                                

Cloning and expression analysis of the anterior parahox genes, Gsh1 and Gsh2 from Xenopus tropicalis., Illes JC, Winterbottom E, Isaacs HV., Dev Dyn. January 1, 2009; 238 (1): 194-203.                                

A water-specific aquaporin involved in aphid osmoregulation., Shakesby AJ, Wallace IS, Isaacs HV, Pritchard J, Roberts DM, Douglas AE., Insect Biochem Mol Biol. January 1, 2009; 39 (1): 1-10.

Characterisation of the fibroblast growth factor dependent transcriptome in early development., Branney PA, Faas L, Steane SE, Pownall ME, Isaacs HV., PLoS One. January 1, 2009; 4 (3): e4951.            

Molecular characterisation of a candidate gut sucrase in the pea aphid, Acyrthosiphon pisum., Price DR, Karley AJ, Ashford DA, Isaacs HV, Pownall ME, Wilkinson HS, Gatehouse JA, Douglas AE., Insect Biochem Mol Biol. April 1, 2007; 37 (4): 307-17.

Expression of enzymes involved in thyroid hormone metabolism during the early development of Xenopus tropicalis., Tindall AJ, Morris ID, Pownall ME, Isaacs HV., Biol Cell. March 1, 2007; 99 (3): 151-63.  

FGF4 regulates blood and muscle specification in Xenopus laevis., Isaacs HV, Deconinck AE, Pownall ME., Biol Cell. March 1, 2007; 99 (3): 165-73.

FGF signal transduction and the regulation of Cdx gene expression., Keenan ID, Sharrard RM, Isaacs HV., Dev Biol. November 15, 2006; 299 (2): 478-88.    

A consensus Oct1 binding site is required for the activity of the Xenopus Cdx4 promoter., Reece-Hoyes JS, Keenan ID, Pownall ME, Isaacs HV., Dev Biol. June 15, 2005; 282 (2): 509-23.              

Xenopus tropicalis peroxidasin gene is expressed within the developing neural tube and pronephric kidney., Tindall AJ, Pownall ME, Morris ID, Isaacs HV., Dev Dyn. February 1, 2005; 232 (2): 377-84.  

A novel role for a nodal-related protein; Xnr3 regulates convergent extension movements via the FGF receptor., Yokota C, Kofron M, Zuck M, Houston DW, Isaacs H, Asashima M, Wylie CC, Heasman J., Development. May 1, 2003; 130 (10): 2199-212.    

An inducible system for the study of FGF signalling in early amphibian development., Pownall ME, Welm BE, Freeman KW, Spencer DM, Rosen JM, Isaacs HV., Dev Biol. April 1, 2003; 256 (1): 89-99.

eFGF is required for activation of XmyoD expression in the myogenic cell lineage of Xenopus laevis., Fisher ME, Isaacs HV, Pownall ME., Development. March 1, 2002; 129 (6): 1307-15.    

Cloning and expression of the Cdx family from the frog Xenopus tropicalis., Reece-Hoyes JS, Keenan ID, Isaacs HV., Dev Dyn. January 1, 2002; 223 (1): 134-40.      

Anteroposterior patterning by mutual repression of orthodenticle and caudal-type transcription factors., Isaacs HV, Andreazzoli M, Slack JM., Evol Dev. January 1, 1999; 1 (3): 143-52.

Expression and functions of FGF-3 in Xenopus development., Lombardo A, Isaacs HV, Slack JM., Int J Dev Biol. November 1, 1998; 42 (8): 1101-7.      

Regulation of Hox gene expression and posterior development by the Xenopus caudal homologue Xcad3., Isaacs HV, Pownall ME, Slack JM., EMBO J. June 15, 1998; 17 (12): 3413-27.

Two phases of Hox gene regulation during early Xenopus development., Pownall ME, Isaacs HV, Slack JM., Curr Biol. May 21, 1998; 8 (11): 673-6.              

New perspectives on the role of the fibroblast growth factor family in amphibian development., Isaacs HV., Cell Mol Life Sci. April 1, 1997; 53 (4): 350-61.

eFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus., Pownall ME, Tucker AS, Slack JM, Isaacs HV., Development. December 1, 1996; 122 (12): 3881-92.                  

The role of fibroblast growth factors in early Xenopus development., Slack JM, Isaacs HV, Song J, Durbin L, Pownall ME., Biochem Soc Symp. January 1, 1996; 62 1-12.

eFGF is expressed in the dorsal midline of Xenopus laevis., Isaacs HV, Pownall ME, Slack JM., Int J Dev Biol. August 1, 1995; 39 (4): 575-9.  

eFGF regulates Xbra expression during Xenopus gastrulation., Isaacs HV, Pownall ME, Slack JM., EMBO J. October 3, 1994; 13 (19): 4469-81.

The role of fibroblast growth factors in early Xenopus development., Slack JM, Isaacs HV., Biochem Soc Trans. August 1, 1994; 22 (3): 585-9.

The Einsteck-method: position and structure of projections formed by implants of a ventral character., Slack JM, Isaacs HV., Dev Biol. January 1, 1994; 161 (1): 313-7.    

Developmental expression of the Xenopus int-2 (FGF-3) gene: activation by mesodermal and neural induction., Tannahill D, Isaacs HV, Close MJ, Peters G, Slack JM., Development. July 1, 1992; 115 (3): 695-702.

Expression of a novel FGF in the Xenopus embryo. A new candidate inducing factor for mesoderm formation and anteroposterior specification., Isaacs HV, Tannahill D, Slack JM., Development. March 1, 1992; 114 (3): 711-20.

Specification of the body plan during Xenopus gastrulation: dorsoventral and anteroposterior patterning of the mesoderm., Slack JM, Isaacs HV, Johnson GE, Lettice LA, Tannahill D, Thompson J., Dev Suppl. January 1, 1992; 143-9.

A mesoderm-inducing factor produced by WEHI-3 murine myelomonocytic leukemia cells is activin A., Albano RM, Godsave SF, Huylebroeck D, Van Nimmen K, Isaacs HV, Slack JM, Smith JC., Development. October 1, 1990; 110 (2): 435-43.

Mesoderm induction by fibroblast growth factor in early Xenopus development., Slack JM, Darlington BG, Gillespie LL, Godsave SF, Isaacs HV, Paterno GD., Philos Trans R Soc Lond B Biol Sci. March 12, 1990; 327 (1239): 75-84.

The role of fibroblast growth factor in early Xenopus development., Slack JM, Darlington BG, Gillespie LL, Godsave SF, Isaacs HV, Paterno GD., Development. January 1, 1989; 107 Suppl 141-8.

Inductive effects of fibroblast growth factor and lithium ion on Xenopus blastula ectoderm., Slack JM, Isaacs HV, Darlington BG., Development. July 1, 1988; 103 (3): 581-90.

Mesoderm-inducing factors: a small class of molecules., Godsave SF, Isaacs HV, Slack JM., Development. March 1, 1988; 102 (3): 555-66.

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