Publications By Ariel Ruiz i Altaba

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Cooperative requirement of the Gli proteins in neurogenesis., Nguyen V, Chokas AL, Stecca B, Ruiz i Altaba A., Development. July 1, 2005; 132 (14): 3267-79.

Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features., Roessler E, Du YZ, Mullor JL, Casas E, Allen WP, Gillessen-Kaesbach G, Roeder ER, Ming JE, Ruiz i Altaba A, Muenke M., Proc Natl Acad Sci U S A. November 11, 2003; 100 (23): 13424-9.

Hexokinase I is a Gli2-responsive gene expressed in the embryonic CNS., Brewster R, Ruiz i Altaba A., Mech Dev. December 1, 2000; 99 (1-2): 159-62.

Gli2 functions in FGF signaling during antero-posterior patterning., Brewster R, Mullor JL, Ruiz i Altaba A., Development. October 1, 2000; 127 (20): 4395-405.

Gli proteins encode context-dependent positive and negative functions: implications for development and disease., Ruiz i Altaba A., Development. June 1, 1999; 126 (14): 3205-16.

Sonic hedgehog regulates the growth and patterning of the cerebellum., Dahmane N, Ruiz i Altaba A., Development. June 1, 1999; 126 (14): 3089-100.

Carboxy-terminally truncated Gli3 proteins associate with Smads., Liu F, Massagué J, Ruiz i Altaba A., Nat Genet. December 1, 1998; 20 (4): 325-6.

Gli/Zic factors pattern the neural plate by defining domains of cell differentiation., Brewster R, Lee J, Ruiz i Altaba A., Nature. June 11, 1998; 393 (6685): 579-83.

Combinatorial Gli gene function in floor plate and neuronal inductions by Sonic hedgehog., Ruiz i Altaba A., Development. June 1, 1998; 125 (12): 2203-12.

Cooperation of intrinsic and extrinsic signals in the elaboration of regional identity in the posterior cerebral cortex., Nothias F, Fishell G, Ruiz i Altaba A., Curr Biol. April 9, 1998; 8 (8): 459-62.

Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours., Dahmane N, Lee J, Robins P, Heller P, Ruiz i Altaba A., Nature. October 23, 1997; 389 (6653): 876-81.

Gli1 is a target of Sonic hedgehog that induces ventral neural tube development., Lee J, Platt KA, Censullo P, Ruiz i Altaba A., Development. July 1, 1997; 124 (13): 2537-52.

Involvement of Livertine, a hepatocyte growth factor family member, in neural morphogenesis., Ruiz i Altaba A, Théry C., Mech Dev. December 1, 1996; 60 (2): 207-20.

Restrictions to floor plate induction by hedgehog and winged-helix genes in the neural tube of frog embryos., Ruiz i Altaba A, Jessell TM, Roelink H., Mol Cell Neurosci. April 1, 1995; 6 (2): 106-21.

Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord., Roelink H, Augsburger A, Heemskerk J, Korzh V, Norlin S, Ruiz i Altaba A, Tanabe Y, Placzek M, Edlund T, Jessell TM., Cell. February 25, 1994; 76 (4): 761-75.

Sequential expression of HNF-3 beta and HNF-3 alpha by embryonic organizing centers: the dorsal lip/node, notochord and floor plate., Ruiz i Altaba A, Prezioso VR, Darnell JE, Jessell TM., Mech Dev. December 1, 1993; 44 (2-3): 91-108.

Ectopic neural expression of a floor plate marker in frog embryos injected with the midline transcription factor Pintallavis., Ruiz i Altaba A, Cox C, Jessell TM, Klar A., Proc Natl Acad Sci U S A. September 1, 1993; 90 (17): 8268-72.

Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis., Ruiz i Altaba A, Jessell TM., Development. September 1, 1992; 116 (1): 81-93.

Planar and vertical signals in the induction and patterning of the Xenopus nervous system., Ruiz i Altaba A., Development. September 1, 1992; 116 (1): 67-80.

Expression of the Xhox3 Homeobox Protein in Xenopus Embryos: Blocking Its Early Function Suggests the Requirement of Xhox3 for Normal Posterior Development: (axial pattern/central nervous system/embryonic mesoderm/homeobox gene/Xenopus laevis)., Ruiz I Altaba A, Choi T, Melton DA., Dev Growth Differ. December 1, 1991; 33 (6): 651-669.

Retinoic acid modifies the pattern of cell differentiation in the central nervous system of neurula stage Xenopus embryos., Ruiz i Altaba A, Jessell TM., Development. August 1, 1991; 112 (4): 945-58.

Retinoic acid modifies mesodermal patterning in early Xenopus embryos., Ruiz i Altaba A, Jessell T., Genes Dev. February 1, 1991; 5 (2): 175-87.

Neural expression of the Xenopus homeobox gene Xhox3: evidence for a patterning neural signal that spreads through the ectoderm., Ruiz i Altaba A., Development. April 1, 1990; 108 (4): 595-604.

Axial patterning and the establishment of polarity in the frog embryo., Ruiz i Altaba A, Melton DA., Trends Genet. February 1, 1990; 6 (2): 57-64.

Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos., Ruiz i Altaba A, Melton DA., Nature. September 7, 1989; 341 (6237): 33-8.

Bimodal and graded expression of the Xenopus homeobox gene Xhox3 during embryonic development., Ruiz i Altaba A, Melton DA., Development. May 1, 1989; 106 (1): 173-83.

Involvement of the Xenopus homeobox gene Xhox3 in pattern formation along the anterior-posterior axis., Ruiz i Altaba A, Melton DA., Cell. April 21, 1989; 57 (2): 317-26.

Localization of mRNA and axis formation during Xenopus embryogenesis., Melton DA, Ruiz i Altaba A, Yisraeli J, Sokol S., Ciba Found Symp. January 1, 1989; 144 16-29; discussion 29-36, 92-8.

Xfin: an embryonic gene encoding a multifingered protein in Xenopus., Ruiz i Altaba A, Perry-O'Keefe H, Melton DA., EMBO J. October 1, 1987; 6 (10): 3065-70.

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