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Profile Publications (82)

Publications By Douglas A. Melton

Results 1 - 50 of 82 results

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Prospective isolation and global gene expression analysis of definitive and visceral endoderm., Sherwood RI, Jitianu C, Cleaver O, Shaywitz DA, Lamenzo JO, Chen AE, Golub TR, Melton DA., Dev Biol. April 15, 2007; 304 (2): 541-55.

Endothelial signaling during development., Cleaver O, Melton DA., Nat Med. June 1, 2003; 9 (6): 661-8.

Development of the pancreas in Xenopus laevis., Kelly OG, Melton DA., Dev Dyn. August 1, 2000; 218 (4): 615-27.                  

Endoderm development: from patterning to organogenesis., Grapin-Botton A, Melton DA., Trends Genet. March 1, 2000; 16 (3): 124-30.

Mixer, a homeobox gene required for endoderm development., Henry GL, Melton DA., Science. July 3, 1998; 281 (5373): 91-6.

Mutant Vg1 ligands disrupt endoderm and mesoderm formation in Xenopus embryos., Joseph EM, Melton DA., Development. July 1, 1998; 125 (14): 2677-85.            

Xnr4: a Xenopus nodal-related gene expressed in the Spemann organizer., Joseph EM, Melton DA., Dev Biol. April 15, 1997; 184 (2): 367-72.        

Nomenclature: vertebrate mediators of TGFbeta family signals., Derynck R, Gelbart WM, Harland RM, Heldin CH, Kern SE, Massagué J, Melton DA, Mlodzik M, Padgett RW, Roberts AB, Smith J, Thomsen GH, Vogelstein B, Wang XF., Cell. October 18, 1996; 87 (2): 173.

Short-range signaling by candidate morphogens of the TGF beta family and evidence for a relay mechanism of induction., Reilly KM, Melton DA., Cell. September 6, 1996; 86 (5): 743-54.

A molecular mechanism for the effect of lithium on development., Klein PS, Melton DA., Proc Natl Acad Sci U S A. August 6, 1996; 93 (16): 8455-9.

Mothers against dpp encodes a conserved cytoplasmic protein required in DPP/TGF-beta responsive cells., Newfeld SJ, Chartoff EH, Graff JM, Melton DA, Gelbart WM., Development. July 1, 1996; 122 (7): 2099-108.  

Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily., Graff JM, Bansal A, Melton DA., Cell. May 17, 1996; 85 (4): 479-87.

Induction of axial mesoderm by zDVR-1, the zebrafish orthologue of Xenopus Vg1., Dohrmann CE, Kessler DS, Melton DA., Dev Biol. April 10, 1996; 175 (1): 108-17.

TGF-beta signals and a pattern in Xenopus laevis endodermal development., Henry GL, Brivanlou IH, Kessler DS, Hemmati-Brivanlou A, Melton DA., Development. March 1, 1996; 122 (3): 1007-15.          

Induction of dorsal mesoderm by soluble, mature Vg1 protein., Kessler DS, Melton DA., Development. July 1, 1995; 121 (7): 2155-64.            

Translational control of activin in Xenopus laevis embryos., Klein PS, Melton DA., Dev Genet. January 1, 1995; 17 (1): 55-64.

Vertebrate embryonic induction: mesodermal and neural patterning., Kessler DS, Melton DA., Science. October 28, 1994; 266 (5185): 596-604.

Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo., Graff JM, Thies RS, Song JJ, Celeste AJ, Melton DA., Cell. October 7, 1994; 79 (1): 169-79.

Induction of mesoderm in Xenopus laevis embryos by translation initiation factor 4E., Klein PS, Melton DA., Science. August 5, 1994; 265 (5173): 803-6.

Mesodermal patterning by an inducer gradient depends on secondary cell-cell communication., Wilson PA, Melton DA., Curr Biol. August 1, 1994; 4 (8): 676-86.

Hormonal regulation of embryogenesis: the formation of mesoderm in Xenopus laevis., Klein PS, Melton DA., Endocr Rev. June 1, 1994; 15 (3): 326-41.

Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity., Hemmati-Brivanlou A, Kelly OG, Melton DA., Cell. April 22, 1994; 77 (2): 283-95.                    

Inhibition of activin receptor signaling promotes neuralization in Xenopus., Hemmati-Brivanlou A, Melton DA., Cell. April 22, 1994; 77 (2): 273-81.            

Xwnt-11: a maternally expressed Xenopus wnt gene., Ku M, Melton DA., Development. December 1, 1993; 119 (4): 1161-73.              

Processed Vg1 protein is an axial mesoderm inducer in Xenopus., Thomsen GH, Melton DA., Cell. August 13, 1993; 74 (3): 433-41.

Expression of activin mRNA during early development in Xenopus laevis., Dohrmann CE, Hemmati-Brivanlou A, Thomsen GH, Fields A, Woolf TM, Melton DA., Dev Biol. June 1, 1993; 157 (2): 474-83.          

Xenopus axis formation: induction of goosecoid by injected Xwnt-8 and activin mRNAs., Steinbeisser H, De Robertis EM, Ku M, Kessler DS, Melton DA., Development. June 1, 1993; 118 (2): 499-507.          

Interaction of Wnt and activin in dorsal mesoderm induction in Xenopus., Sokol SY, Melton DA., Dev Biol. December 1, 1992; 154 (2): 348-55.

A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos., Hemmati-Brivanlou A, Melton DA., Nature. October 15, 1992; 359 (6396): 609-14.

Specificity of antisense oligonucleotides in vivo., Woolf TM, Melton DA, Jennings CG., Proc Natl Acad Sci U S A. August 15, 1992; 89 (16): 7305-9.

Involvement of p21ras in Xenopus mesoderm induction., Whitman M, Melton DA., Nature. May 21, 1992; 357 (6375): 252-4.

Embryonic expression and functional analysis of a Xenopus activin receptor., Hemmati-Brivanlou A, Wright DA, Melton DA., Dev Dyn. May 1, 1992; 194 (1): 1-11.        

Vegetal messenger RNA localization directed by a 340-nt RNA sequence element in Xenopus oocytes., Mowry KL, Melton DA., Science. February 21, 1992; 255 (5047): 991-4.

Expression of the Xhox3 Homeobox Protein in Xenopus Embryos: Blocking Its Early Function Suggests the Requirement of Xhox3 for Normal Posterior Development: (axial pattern/central nervous system/embryonic mesoderm/homeobox gene/Xenopus laevis)., Ruiz I Altaba A, Choi T, Melton DA., Dev Growth Differ. December 1, 1991; 33 (6): 651-669.

Injected Wnt RNA induces a complete body axis in Xenopus embryos., Sokol S, Christian JL, Moon RT, Melton DA., Cell. November 15, 1991; 67 (4): 741-52.              

Pre-existent pattern in Xenopus animal pole cells revealed by induction with activin., Sokol S, Melton DA., Nature. May 30, 1991; 351 (6325): 409-11.

Pattern formation during animal development., Melton DA., Science. April 12, 1991; 252 (5003): 234-41.

The Xenopus localized messenger RNA An3 may encode an ATP-dependent RNA helicase., Gururajan R, Perry-O'Keefe H, Melton DA, Weeks DL., Nature. February 21, 1991; 349 (6311): 717-9.

In situ hyridization., O'Keefe HP, Melton DA, Ferreiro B, Kintner C., Methods Cell Biol. January 1, 1991; 36 443-63.

Assays for gene function in developing Xenopus embryos., Vize PD, Melton DA, Hemmati-Brivanlou A, Harland RM., Methods Cell Biol. January 1, 1991; 36 367-87.

Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures., Thomsen G, Woolf T, Whitman M, Sokol S, Vaughan J, Vale W, Melton DA., Cell. November 2, 1990; 63 (3): 485-93.

A mouse macrophage factor induces head structures and organizes a body axis in Xenopus., Sokol S, Wong GG, Melton DA., Science. August 3, 1990; 249 (4968): 561-4.

The stability, toxicity and effectiveness of unmodified and phosphorothioate antisense oligodeoxynucleotides in Xenopus oocytes and embryos., Woolf TM, Jennings CG, Rebagliati M, Melton DA., Nucleic Acids Res. April 11, 1990; 18 (7): 1763-9.

A two-step model for the localization of maternal mRNA in Xenopus oocytes: involvement of microtubules and microfilaments in the translocation and anchoring of Vg1 mRNA., Yisraeli JK, Sokol S, Melton DA., Development. February 1, 1990; 108 (2): 289-98.              

Axial patterning and the establishment of polarity in the frog embryo., Ruiz i Altaba A, Melton DA., Trends Genet. February 1, 1990; 6 (2): 57-64.

Identification of a novel transforming growth factor-beta (TGF-beta 5) mRNA in Xenopus laevis., Kondaiah P, Sands MJ, Smith JM, Fields A, Roberts AB, Sporn MB, Melton DA., J Biol Chem. January 15, 1990; 265 (2): 1089-93.      

Signal transduction during mesoderm induction in Xenopus., Whitman M, Melton DA., J Reprod Fertil Suppl. January 1, 1990; 42 249-54.

Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos., Ruiz i Altaba A, Melton DA., Nature. September 7, 1989; 341 (6237): 33-8.

Localized synthesis of the Vg1 protein during early Xenopus development., Tannahill D, Melton DA., Development. August 1, 1989; 106 (4): 775-85.

Induction of mesoderm by a viral oncogene in early Xenopus embryos., Whitman M, Melton DA., Science. May 19, 1989; 244 (4906): 803-6.

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