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Summary Expression Phenotypes Gene Literature (68) GO Terms (3) Nucleotides (67) Proteins (35) Interactants (139) Wiki
XB-GENEPAGE-487853

Papers associated with aqp4



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Advancements in the use of xenopus oocytes for modelling neurological disease for novel drug discovery., O'Connor EC, Kambara K, Bertrand D., Expert Opin Drug Discov. February 1, 2024; 19 (2): 173-187.      


Toward New AQP4 Inhibitors: ORI-TRN-002., Thormann M, Traube N, Yehia N, Koestler R, Galabova G, MacAulay N, Toft-Bertelsen TL., Int J Mol Sci. January 11, 2024; 25 (2):         


A Focal Impact Model of Traumatic Brain Injury in Xenopus Tadpoles Reveals Behavioral Alterations, Neuroinflammation, and an Astroglial Response., Spruiell Eldridge SL, Teetsel JFK, Torres RA, Ulrich CH, Shah VV, Singh D, Zamora MJ, Zamora S, Sater AK., Int J Mol Sci. July 8, 2022; 23 (14):                         


Inhibition of the Aquaporin-1 Cation Conductance by Selected Furan Compounds Reduces Red Blood Cell Sickling., Chow PH, Cox CD, Pei JV, Anabaraonye N, Nourmohammadi S, Henderson SW, Martinac B, Abdulmalik O, Yool AJ., Front Pharmacol. October 1, 2021; 12 794791.                    


Clearance of activity-evoked K+ transients and associated glia cell swelling occur independently of AQP4: A study with an isoform-selective AQP4 inhibitor., Toft-Bertelsen TL, Larsen BR, Christensen SK, Khandelia H, Waagepetersen HS, MacAulay N., Glia. January 1, 2021; 69 (1): 28-41.


Aquaporin expression in the alimentary canal of the honey bee Apis mellifera L. (Hymenoptera: Apidae) and functional characterization of Am_Eglp 1., Linhares Lino de Souza D, Serrão JE, Hansen IA., PLoS One. September 21, 2020; 15 (9): e0236724.      


Specialized stellate cells offer a privileged route for rapid water flux in Drosophila renal tubule., Cabrero P, Terhzaz S, Dornan AJ, Ghimire S, Holmes HL, Turin DR, Romero MF, Davies SA, Dow JAT., Proc Natl Acad Sci U S A. January 21, 2020; 117 (3): 1779-1787.              


Volume sensing in the transient receptor potential vanilloid 4 ion channel is cell type-specific and mediated by an N-terminal volume-sensing domain., Toft-Bertelsen TL, Yarishkin O, Redmon S, Phuong TTT, Križaj D, MacAulay N., J Biol Chem. November 29, 2019; 294 (48): 18421-18434.                


Aquaporin-4 facilitator TGN-073 promotes interstitial fluid circulation within the blood-brain barrier: [17O]H2O JJVCPE MRI study., Huber VJ, Igarashi H, Ueki S, Kwee IL, Nakada T., Neuroreport. June 13, 2018; 29 (9): 697-703.              


A de novo Ser111Thr variant in aquaporin-4 in a patient with intellectual disability, transient signs of brain ischemia, transient cardiac hypertrophy, and progressive gait disturbance., Berland S, Toft-Bertelsen TL, Aukrust I, Byska J, Vaudel M, Bindoff LA, MacAulay N, Houge G., Cold Spring Harb Mol Case Stud. February 1, 2018; 4 (1):       


Targeted deletion of the aquaglyceroporin AQP9 is protective in a mouse model of Parkinson's disease., Stahl K, Rahmani S, Prydz A, Skauli N, MacAulay N, Mylonakou MN, Torp R, Skare Ø, Berg T, Leergaard TB, Paulsen RE, Ottersen OP, Amiry-Moghaddam M., PLoS One. January 1, 2018; 13 (3): e0194896.                


Divalent Cations Regulate the Ion Conductance Properties of Diverse Classes of Aquaporins., Kourghi M, Nourmohammadi S, Pei JV, Qiu J, McGaughey S, Tyerman SD, Byrt CS, Yool AJ., Int J Mol Sci. November 3, 2017; 18 (11):               


When size matters: transient receptor potential vanilloid 4 channel as a volume-sensor rather than an osmo-sensor., Toft-Bertelsen TL, Križaj D, MacAulay N., J Physiol. June 1, 2017; 595 (11): 3287-3302.


Specific Palmitoyltransferases Associate with and Activate the Epithelial Sodium Channel., Mukherjee A, Wang Z, Kinlough CL, Poland PA, Marciszyn AL, Montalbetti N, Carattino MD, Butterworth MB, Kleyman TR, Hughey RP., J Biol Chem. March 10, 2017; 292 (10): 4152-4163.


Rhubarb extract partially improves mucosal integrity in chemotherapy-induced intestinal mucositis., Bajic JE, Eden GL, Lampton LS, Cheah KY, Lymn KA, Pei JV, Yool AJ, Howarth GS., World J Gastroenterol. October 7, 2016; 22 (37): 8322-8333.              


Differential Inhibition of Water and Ion Channel Activities of Mammalian Aquaporin-1 by Two Structurally Related Bacopaside Compounds Derived from the Medicinal Plant Bacopa monnieri., Pei JV, Kourghi M, De Ieso ML, Campbell EM, Dorward HS, Hardingham JE, Yool AJ., Mol Pharmacol. October 1, 2016; 90 (4): 496-507.


Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy., Sicca F, Ambrosini E, Marchese M, Sforna L, Servettini I, Valvo G, Brignone MS, Lanciotti A, Moro F, Grottesi A, Catacuzzeno L, Baldini S, Hasan S, D'Adamo MC, Franciolini F, Molinari P, Santorelli FM, Pessia M., Sci Rep. September 28, 2016; 6 34325.            


Aquaporin 4 as a NH3 Channel., Assentoft M, Kaptan S, Schneider HP, Deitmer JW, de Groot BL, MacAulay N., J Biol Chem. September 2, 2016; 291 (36): 19184-95.


H95 Is a pH-Dependent Gate in Aquaporin 4., Kaptan S, Assentoft M, Schneider HP, Fenton RA, Deitmer JW, MacAulay N, de Groot BL., Structure. December 1, 2015; 23 (12): 2309-2318.


TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Müller Glia., Jo AO, Ryskamp DA, Phuong TT, Verkman AS, Yarishkin O, MacAulay N, Križaj D., J Neurosci. September 30, 2015; 35 (39): 13525-37.                  


Vasopressin receptors V1a and V2 are not osmosensors., Lykke K, Assentoft M, Fenton RA, Rosenkilde MM, MacAulay N., Physiol Rep. August 1, 2015; 3 (8):         


Insect glycerol transporters evolved by functional co-option and gene replacement., Finn RN, Chauvigné F, Stavang JA, Belles X, Cerdà J., Nat Commun. July 17, 2015; 6 7814.        


The pH sensitivity of Aqp0 channels in tetraploid and diploid teleosts., Chauvigné F, Zapater C, Stavang JA, Taranger GL, Cerdà J, Finn RN., FASEB J. May 1, 2015; 29 (5): 2172-84.              


AQP4 plasma membrane trafficking or channel gating is not significantly modulated by phosphorylation at COOH-terminal serine residues., Assentoft M, Larsen BR, Olesen ET, Fenton RA, MacAulay N., Am J Physiol Cell Physiol. November 15, 2014; 307 (10): C957-65.


Atomic force microscopy on plasma membranes from Xenopus laevis oocytes containing human aquaporin 4., Orsini F, Santacroce M, Cremona A, Gosvami NN, Lascialfari A, Hoogenboom BW., J Mol Recognit. November 1, 2014; 27 (11): 669-75.


Identification of a point mutation impairing the binding between aquaporin-4 and neuromyelitis optica autoantibodies., Pisani F, Mola MG, Simone L, Rosito S, Alberga D, Mangiatordi GF, Lattanzi G, Nicolotti O, Frigeri A, Svelto M, Nicchia GP., J Biol Chem. October 31, 2014; 289 (44): 30578-30589.


Establishment of monoclonal antibodies against the extracellular domain that block binding of NMO-IgG to AQP4., Miyazaki K, Abe Y, Iwanari H, Suzuki Y, Kikuchi T, Ito T, Kato J, Kusano-Arai O, Takahashi T, Nishiyama S, Ikeshima-Kataoka H, Tsuji S, Arimitsu T, Kato Y, Sakihama T, Toyama Y, Fujihara K, Hamakubo T, Yasui M., J Neuroimmunol. July 15, 2013; 260 (1-2): 107-16.


Phosphorylation of rat aquaporin-4 at Ser(111) is not required for channel gating., Assentoft M, Kaptan S, Fenton RA, Hua SZ, de Groot BL, MacAulay N., Glia. July 1, 2013; 61 (7): 1101-12.


AqF026 is a pharmacologic agonist of the water channel aquaporin-1., Yool AJ, Morelle J, Cnops Y, Verbavatz JM, Campbell EM, Beckett EA, Booker GW, Flynn G, Devuyst O., J Am Soc Nephrol. June 1, 2013; 24 (7): 1045-52.


Relative CO(2)/NH(3) selectivities of mammalian aquaporins 0-9., Geyer RR, Musa-Aziz R, Qin X, Boron WF., Am J Physiol Cell Physiol. May 15, 2013; 304 (10): C985-94.


Aquaporin-2: new mutations responsible for autosomal-recessive nephrogenic diabetes insipidus-update and epidemiology., Bichet DG, El Tarazi A, Matar J, Lussier Y, Arthus MF, Lonergan M, Bockenhauer D, Bissonnette P., Clin Kidney J. June 1, 2012; 5 (3): 195-202.          


Aquaporin 4 is a Ubiquitously Expressed Isoform in the Dogfish (Squalus acanthias) Shark., Cutler CP, Maciver B, Cramb G, Zeidel M., Front Physiol. January 10, 2012; 2 107.                  


D184E mutation in aquaporin-4 gene impairs water permeability and links to deafness., Nicchia GP, Ficarella R, Rossi A, Giangreco I, Nicolotti O, Carotti A, Pisani F, Estivill X, Gasparini P, Svelto M, Frigeri A., Neuroscience. December 1, 2011; 197 80-8.


Sharpey-Schafer lecture: gas channels., Boron WF., Exp Physiol. December 1, 2010; 95 (12): 1107-30.                      


Cloning and characterization of a zebrafish homologue of human AQP1: a bifunctional water and gas channel., Chen LM, Zhao J, Musa-Aziz R, Pelletier MF, Drummond IA, Boron WF., Am J Physiol Regul Integr Comp Physiol. November 1, 2010; 299 (5): R1163-74.


Na(+)-K (+)-2Cl (-) cotransport inhibitor attenuates cerebral edema following experimental stroke via the perivascular pool of aquaporin-4., Migliati ER, Amiry-Moghaddam M, Froehner SC, Adams ME, Ottersen OP, Bhardwaj A., Neurocrit Care. August 1, 2010; 13 (1): 123-31.


Differential water permeability and regulation of three aquaporin 4 isoforms., Fenton RA, Moeller HB, Zelenina M, Snaebjornsson MT, Holen T, MacAulay N., Cell Mol Life Sci. March 1, 2010; 67 (5): 829-40.


Vasopressin-dependent short-term regulation of aquaporin 4 expressed in Xenopus oocytes., Moeller HB, Fenton RA, Zeuthen T, Macaulay N., Neuroscience. December 29, 2009; 164 (4): 1674-84.


Inhibition of aquaporin-1 and aquaporin-4 water permeability by a derivative of the loop diuretic bumetanide acting at an internal pore-occluding binding site., Migliati E, Meurice N, DuBois P, Fang JS, Somasekharan S, Beckett E, Flynn G, Yool AJ., Mol Pharmacol. July 1, 2009; 76 (1): 105-12.


Relative CO2/NH3 selectivities of AQP1, AQP4, AQP5, AmtB, and RhAG., Musa-Aziz R, Chen LM, Pelletier MF, Boron WF., Proc Natl Acad Sci U S A. March 31, 2009; 106 (13): 5406-11.


Inhibition of aquaporin 4 by antiepileptic drugs., Huber VJ, Tsujita M, Kwee IL, Nakada T., Bioorg Med Chem. January 1, 2009; 17 (1): 418-24.


Mercury chloride decreases the water permeability of aquaporin-4-reconstituted proteoliposomes., Yukutake Y, Tsuji S, Hirano Y, Adachi T, Takahashi T, Fujihara K, Agre P, Yasui M, Suematsu M., Biol Cell. June 1, 2008; 100 (6): 355-63.


New isoforms of rat Aquaporin-4., Moe SE, Sorbo JG, Sogaard R, Zeuthen T, Petter Ottersen O, Holen T., Genomics. April 1, 2008; 91 (4): 367-77.


Organization of the pronephric kidney revealed by large-scale gene expression mapping., Raciti D, Reggiani L, Geffers L, Jiang Q, Bacchion F, Subrizi AE, Clements D, Tindal C, Davidson DR, Kaissling B, Brändli AW., Genome Biol. January 1, 2008; 9 (5): R84.                                                                        


Zinc modulation of water permeability reveals that aquaporin 0 functions as a cooperative tetramer., Németh-Cahalan KL, Kalman K, Froger A, Hall JE., J Gen Physiol. November 1, 2007; 130 (5): 457-64.        


Two distinct aquaporin-4 cDNAs isolated from medullary cone of quail kidney., Yang Y, Cui Y, Fan Z, Cook GA, Nishimura H., Comp Biochem Physiol A Mol Integr Physiol. May 1, 2007; 147 (1): 84-93.


Molecular characterization of water-selective AQP (EbAQP4) in hagfish: insight into ancestral origin of AQP4., Nishimoto G, Sasaki G, Yaoita E, Nameta M, Li H, Furuse K, Fujinaka H, Yoshida Y, Mitsudome A, Yamamoto T., Am J Physiol Regul Integr Comp Physiol. January 1, 2007; 292 (1): R644-51.


The structure of aquaporins., Gonen T, Walz T., Q Rev Biophys. November 1, 2006; 39 (4): 361-96.


Aquaporin-11: a channel protein lacking apparent transport function expressed in brain., Gorelick DA, Praetorius J, Tsunenari T, Nielsen S, Agre P., BMC Biochem. May 1, 2006; 7 14.              


Molecular basis of pH and Ca2+ regulation of aquaporin water permeability., Németh-Cahalan KL, Kalman K, Hall JE., J Gen Physiol. May 1, 2004; 123 (5): 573-80.            

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