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Summary Expression Phenotypes Gene Literature (234) GO Terms (11) Nucleotides (370) Proteins (50) Interactants (1557) Wiki
XB-GENEPAGE-484285

Papers associated with tp53



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Activation of P53 pathway contributes to Xenopus hybrid inviability., Shi Z, Liu G, Jiang H, Shi S, Zhang X, Deng Y, Chen Y., Proc Natl Acad Sci U S A. May 23, 2023; 120 (21): e2303698120.

Disruption of tp53 leads to cutaneous nevus and melanoma formation in Xenopus tropicalis., Ran R, Li L, Shi Z, Liu G, Jiang H, Fang L, Xu T, Huang J, Chen W, Chen Y., Mol Oncol. October 1, 2022; 16 (19): 3554-3567.

Engraftment of Allotransplanted Tumor Cells in Adult rag2 Mutant Xenopus tropicalis., Tulkens D, Dimitrakopoulou D, Boelens M, Van Nieuwenhuysen T, Demuynck S, Toussaint W, Creytens D, Van Vlierberghe P, Vleminckx K, Vleminckx K., Cancers (Basel). September 20, 2022; 14 (19):


Functions of block of proliferation 1 during anterior development in Xenopus laevis., Gärtner C, Meßmer A, Dietmann P, Kühl M, Kühl SJ., PLoS One. August 2, 2022; 17 (8): e0273507.                        

Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development., Sun J, Yoon J, Lee M, Lee HK, Hwang YS, Daar IO., Cell Rep. February 1, 2022; 38 (5): 110312.                                          

Systematic mapping of rRNA 2'-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis., Delhermite J, Tafforeau L, Sharma S, Marchand V, Wacheul L, Lattuca R, Desiderio S, Motorin Y, Bellefroid E, Lafontaine DLJ., PLoS Genet. January 18, 2022; 18 (1): e1010012.                                                              

Developmental and Injury-induced Changes in DNA Methylation in Regenerative versus Non-regenerative Regions of the Vertebrate Central Nervous System., Reverdatto S, Prasad A, Belrose JL, Zhang X, Sammons MA, Gibbs KM, Szaro BG., BMC Genomics. January 4, 2022; 23 (1): 2.                      

The Ribosomal Protein L5 Functions During Xenopus Anterior Development Through Apoptotic Pathways., Schreiner C, Kernl B, Dietmann P, Riegger RJ, Kühl M, Kühl SJ., Front Cell Dev Biol. January 1, 2022; 10 777121.                        

Temporal transcriptomic profiling reveals dynamic changes in gene expression of Xenopus animal cap upon activin treatment., Satou-Kobayashi Y, Kim JD, Fukamizu A, Asashima M., Sci Rep. July 15, 2021; 11 (1): 14537.          

Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness., Cheng J, Tsuda M, Okolotowicz K, Dwyer M, Bushway PJ, Colas AR, Lancman JJ, Schade D, Perea-Gil I, Bruyneel AAN, Lee J, Vadgama N, Quach J, McKeithan WL, Biechele TL, Wu JC, Moon RT, Si Dong PD, Karakikes I, Cashman JR, Mercola M., Cell Chem Biol. May 20, 2021; 28 (5): 625-635.e5.

The Multifaceted Roles of USP15 in Signal Transduction., Das T, Song EJ, Kim EE., Int J Mol Sci. April 29, 2021; 22 (9):       

Identification of a unique endoplasmic retention motif in the Xenopus GIRK5 channel and its contribution to oocyte maturation., Rangel-Garcia CI, Salvador C, Chavez-Garcia K, Diaz-Bello B, Lopez-Gonzalez Z, Vazquez-Cruz L, Angel Vazquez-Martinez J, Ortiz-Navarrete V, Riveros-Rosas H, Escobar LI., FEBS Open Bio. April 1, 2021; 11 (4): 1093-1108.            

Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant., Magnussen HM, Huang DT., J Mol Biol. March 5, 2021; 433 (5): 166807.

High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instability., Matson DR, Denu RA, Zasadil LM, Burkard ME, Weaver BA, Flynn C, Stukenberg PT., BMC Cancer. February 23, 2021; 21 (1): 186.

Rab11fip5 regulates telencephalon development via ephrinB1 recycling., Yoon J, Garo J, Lee M, Sun J, Hwang YS, Daar IO., Development. February 2, 2021; 148 (3):                                                             

Function and molecular mechanisms of APE2 in genome and epigenome integrity., Lin Y, McMahon A, Driscoll G, Bullock S, Zhao J, Yan S., Mutat Res Rev Mutat Res. January 1, 2021; 787 108347.

Tumor-Suppressive MicroRNA-216b Binds to TPX2, Activating the p53 Signaling in Human Cutaneous Squamous Cell Carcinoma., Feng C, Zhang HL, Zeng A, Bai M, Wang XJ., Mol Ther Nucleic Acids. June 5, 2020; 20 186-195.            

Sub-lethal effects of calcium dinonylnaphthalenesulfonate on Western clawed frog embryos., Wallace SJ, Leclerc AJA, Prosser R, de Solla SR, Balakrishnan V, Langlois VS., Comp Biochem Physiol Part D Genomics Proteomics. June 1, 2020; 34 100658.              

PACT/PRKRA and p53 regulate transcriptional activity of DMRT1., Fujitani K, Otomo A, Nagayama Y, Tachibana T, Kato R, Kawashima Y, Kodera Y, Kato T, Takada S, Tamura K, Takamatsu N, Ito M., Genet Mol Biol. March 30, 2020; 43 (2): e20190017.        

Understanding MAPK Signaling Pathways in Apoptosis., Yue J, López JM., Int J Mol Sci. March 28, 2020; 21 (7):           

RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis., Naert T, Dimitrakopoulou D, Tulkens D, Demuynck S, Carron M, Noelanders R, Eeckhout L, Van Isterdael G, Deforce D, Vanhove C, Van Dorpe J, Creytens D, Vleminckx K, Vleminckx K., Oncogene. March 1, 2020; 39 (13): 2692-2706.          

Dehydration stress alters the mitogen-activated-protein kinase signaling and chaperone stress response in Xenopus laevis., Wu CW, Tessier SN, Storey KB., Comp Biochem Physiol B Biochem Mol Biol. January 1, 2020; 246-247 110461.

Repression of Inappropriate Gene Expression in the Vertebrate Embryonic Ectoderm., Reich S, Weinstein DC., Genes (Basel). November 6, 2019; 10 (11):         

NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress., Han D, Schomacher L, Schüle KM, Mallick M, Musheev MU, Karaulanov E, Krebs L, von Seggern A, Niehrs C., Elife. September 30, 2019; 8                                     

Characteristics of in Vivo Model Systems for Ovarian Cancer Studies., Tudrej P, Kujawa KA, Cortez AJ, Lisowska KM., Diagnostics (Basel). September 14, 2019; 9 (3):         

Morpholinos Do Not Elicit an Innate Immune Response during Early Xenopus Embryogenesis., Paraiso KD, Blitz IL, Zhou JJ, Cho KWY., Dev Cell. May 20, 2019; 49 (4): 643-650.e3.        

X-linked α-thalassemia with mental retardation is downstream of protein kinase A in the meiotic cell cycle signaling cascade in Xenopus oocytes and is dynamically regulated in response to DNA damage†., O'Shea LC, Fair T, Hensey C., Biol Reprod. May 1, 2019; 100 (5): 1238-1249.

Dissociation Process of a MDM2/p53 Complex Investigated by Parallel Cascade Selection Molecular Dynamics and the Markov State Model., Tran DP, Kitao A., J Phys Chem B. March 21, 2019; 123 (11): 2469-2478.

DNp73-induced degradation of tyrosinase links depigmentation with EMT-driven melanoma progression., Fürst K, Steder M, Logotheti S, Angerilli A, Spitschak A, Marquardt S, Schumacher T, Engelmann D, Herchenröder O, Rupp RAW, Pützer BM., Cancer Lett. February 1, 2019; 442 299-309.

Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer., Chen M, Zhang H, Zhang G, Zhong A, Ma Q, Kai J, Tong Y, Xie S, Wang Y, Zheng H, Guo L, Lu R., Biochem Biophys Res Commun. December 9, 2018; 507 (1-4): 74-82.          

AKT signaling displays multifaceted functions in neural crest development., Sittewelle M, Monsoro-Burq AH., Dev Biol. December 1, 2018; 444 Suppl 1 S144-S155.

TPX2 level correlates with cholangiocarcinoma cell proliferation, apoptosis, and EMT., Zou Z, Zheng B, Li J, Lv X, Zhang H, Yu F, Kong L, Li Y, Yu M, Fang L, Liang B., Biomed Pharmacother. November 1, 2018; 107 1286-1293.

Characterization of a Protein Phosphatase Type-1 and a Kinase Anchoring Protein in Plasmodium falciparum., Lenne A, De Witte C, Tellier G, Hollin T, Aliouat EM, Martoriati A, Cailliau K, Saliou JM, Khalife J, Pierrot C., Front Microbiol. October 31, 2018; 9 2617.              

Photoactivation of MDM2 Inhibitors: Controlling Protein-Protein Interaction with Light., Hansen MJ, Feringa FM, Kobauri P, Szymanski W, Medema RH, Feringa BL., J Am Chem Soc. October 17, 2018; 140 (41): 13136-13141.

Xenopus SOX5 enhances myogenic transcription indirectly through transrepression., Della Gaspera B, Chesneau A, Weill L, Charbonnier F, Chanoine C., Dev Biol. October 15, 2018; 442 (2): 262-275.                    

Identification of Drivers of Aneuploidy in Breast Tumors., Pfister K, Pipka JL, Chiang C, Liu Y, Clark RA, Keller R, Skoglund P, Guertin MJ, Hall IM, Stukenberg PT., Cell Rep. May 29, 2018; 23 (9): 2758-2769.                          

Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus., Gentsch GE, Spruce T, Monteiro RS, Owens NDL, Martin SR, Smith JC., Dev Cell. March 12, 2018; 44 (5): 597-610.e10.                                            

TPX2-p53-GLIPR1 regulatory circuitry in cell proliferation, invasion, and tumor growth of bladder cancer., Yan L, Li Q, Yang J, Qiao B., J Cell Biochem. February 1, 2018; 119 (2): 1791-1803.

Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders., Calo E, Gu B, Bowen ME, Aryan F, Zalc A, Liang J, Flynn RA, Swigut T, Chang HY, Attardi LD, Wysocka J., Nature. February 1, 2018; 554 (7690): 112-117.

Targeted Base Editing via RNA-Guided Cytidine Deaminases in Xenopus laevis Embryos., Park DS, Yoon M, Kweon J, Jang AH, Kim Y, Choi SC., Mol Cells. November 30, 2017; 40 (11): 823-827.    

Regulatory remodeling in the allo-tetraploid frog Xenopus laevis., Elurbe DM, Paranjpe SS, Georgiou G, van Kruijsbergen I, Bogdanovic O, Gibeaux R, Heald R, Lister R, Huynen MA, van Heeringen SJ, Veenstra GJC., Genome Biol. October 24, 2017; 18 (1): 198.              

Two-Element Transcriptional Regulation in the Canonical Wnt Pathway., Kim K, Cho J, Hilzinger TS, Nunns H, Liu A, Ryba BE, Goentoro L., Curr Biol. August 7, 2017; 27 (15): 2357-2364.e5.                

Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., Zhang Z, Lei A, Xu L, Chen L, Chen Y, Chen Y, Zhang X, Gao Y, Yang X, Zhang M, Cao Y, Cao Y., J Biol Chem. August 4, 2017; 292 (31): 12842-12859.        

Lineage commitment of embryonic cells involves MEK1-dependent clearance of pluripotency regulator Ventx2., Scerbo P, Marchal L, Kodjabachian L., Elife. June 27, 2017; 6                               

High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Michiue T, Yamamoto T, Yasuoka Y, Goto T, Ikeda T, Nagura K, Nakayama T, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 270-290.                  

The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis., Gao Q, Zhang J, Wang X, Liu Y, He R, Liu X, Wang F, Feng J, Yang D, Wang Z, Meng A, Yan X., Nat Commun. June 7, 2017; 8 15279.              

The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis., Potapova T, Gorbsky GJ., Biology (Basel). February 8, 2017; 6 (1):                 

Shaping Chromatin in the Nucleus: The Bricks and the Architects., Sitbon D, Podsypanina K, Yadav T, Almouzni G., Cold Spring Harb Symp Quant Biol. January 1, 2017; 82 1-14.            

Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors., Kaminski MM, Tosic J, Kresbach C, Engel H, Klockenbusch J, Müller AL, Pichler R, Grahammer F, Kretz O, Huber TB, Walz G, Arnold SJ, Lienkamp SS., Nat Cell Biol. December 1, 2016; 18 (12): 1269-1280.                  

Cyclin F-Mediated Degradation of SLBP Limits H2A.X Accumulation and Apoptosis upon Genotoxic Stress in G2., Dankert JF, Rona G, Clijsters L, Geter P, Skaar JR, Bermudez-Hernandez K, Sassani E, Fenyö D, Ueberheide B, Schneider R, Pagano M., Mol Cell. November 3, 2016; 64 (3): 507-519.

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