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Summary Expression Phenotypes Gene Literature (27) GO Terms (1) Nucleotides (67) Proteins (45) Interactants (67) Wiki
XB-GENEPAGE-876750

Papers associated with pou2f2



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Active Pharmaceutical Ingredient Uptake by Zebrafish (Danio rerio) Oct2 (slc22a2) Transporter Expressed in Xenopus laevis Oocytes., Chang ED, Owen SF, Hogstrand C, Bury NR., Environ Toxicol Chem. December 1, 2022; 41 (12): 2993-2998.

Dual actions on gout flare and acute kidney injury along with enhanced renal transporter activities by Yokuininto, a Kampo medicine., Lee SH, Lee HS, Park G, Oh SM, Oh DS., BMC Complement Altern Med. March 12, 2019; 19 (1): 57.        

Imatinib Uptake into Cells is Not Mediated by Organic Cation Transporters OCT1, OCT2, or OCT3, But is Influenced by Extracellular pH., Blanc Mettral J, Faller N, Cruchon S, Sottas L, Buclin T, Schild L, Choong E, Nahimana A, Decosterd LA., Drug Metab Lett. January 1, 2019; 13 (2): 102-110.

Comprehensive Substrate Characterization of 22 Antituberculosis Drugs for Multiple Solute Carrier (SLC) Uptake Transporters In Vitro., Parvez MM, Kaisar N, Shin HJ, Lee YJ, Shin JG., Antimicrob Agents Chemother. August 27, 2018; 62 (9):


Retention of duplicated ITAM-containing transmembrane signaling subunits in the tetraploid amphibian species Xenopus laevis., Guselnikov SV, Grayfer L, De Jesús Andino F, Rogozin IB, Robert J, Taranin AV., Dev Comp Immunol. November 1, 2015; 53 (1): 158-68.            

Edoxaban transport via P-glycoprotein is a key factor for the drug's disposition., Mikkaichi T, Yoshigae Y, Masumoto H, Imaoka T, Rozehnal V, Fischer T, Okudaira N, Izumi T., Drug Metab Dispos. April 1, 2014; 42 (4): 520-8.

Polyamine transport by the polyspecific organic cation transporters OCT1, OCT2, and OCT3., Sala-Rabanal M, Li DC, Dake GR, Kurata HT, Inyushin M, Skatchkov SN, Nichols CG., Mol Pharm. April 1, 2013; 10 (4): 1450-8.

Charge-to-substrate ratio during organic cation uptake by rat OCT2 is voltage dependent and altered by exchange of glutamate 448 with glutamine., Schmitt BM, Gorbunov D, Schlachtbauer P, Egenberger B, Gorboulev V, Wischmeyer E, Müller T, Koepsell H., Am J Physiol Renal Physiol. April 1, 2009; 296 (4): F709-22.

Genetic variants of organic cation transporter 2 (OCT2) significantly reduce metformin uptake in oocytes., Song IS, Shin HJ, Shin JG., Xenobiotica. September 1, 2008; 38 (9): 1252-62.

Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity., Sturm A, Gorboulev V, Gorbunov D, Keller T, Volk C, Schmitt BM, Schlachtbauer P, Ciarimboli G, Koepsell H., Am J Physiol Renal Physiol. September 1, 2007; 293 (3): F767-79.

3-Hydroxyglutaric acid is transported via the sodium-dependent dicarboxylate transporter NaDC3., Stellmer F, Keyser B, Burckhardt BC, Koepsell H, Streichert T, Glatzel M, Jabs S, Thiem J, Herdering W, Koeller DM, Goodman SI, Lukacs Z, Ullrich K, Burckhardt G, Braulke T, Mühlhausen C., J Mol Med (Berl). July 1, 2007; 85 (7): 763-70.

Alkali cation binding and permeation in the rat organic cation transporter rOCT2., Schmitt BM, Koepsell H., J Biol Chem. July 1, 2005; 280 (26): 24481-90.

Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium., Lips KS, Volk C, Schmitt BM, Pfeil U, Arndt P, Miska D, Ermert L, Kummer W, Koepsell H., Am J Respir Cell Mol Biol. July 1, 2005; 33 (1): 79-88.

Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney., Ishiguro N, Saito A, Yokoyama K, Morikawa M, Igarashi T, Tamai I., Drug Metab Dispos. April 1, 2005; 33 (4): 495-9.

Molecular evidence of organic ion transporters in the rat adrenal cortex with adrenocorticotropin-regulated zonal expression., Béery E, Middel P, Bahn A, Willenberg HS, Hagos Y, Koepsell H, Bornstein SR, Müller GA, Burckhardt G, Steffgen J., Endocrinology. October 1, 2003; 144 (10): 4519-26.

The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP., Schlatter E, Mönnich V, Cetinkaya I, Mehrens T, Ciarimboli G, Hirsch JR, Popp C, Koepsell H., J Membr Biol. October 1, 2002; 189 (3): 237-44.

Functional characterization of mouse cation transporter mOCT2 compared with mOCT1., Kakehi M, Koyabu N, Nakamura T, Uchiumi T, Kuwano M, Ohtani H, Sawada Y., Biochem Biophys Res Commun. August 23, 2002; 296 (3): 644-50.        

Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function., Leabman MK, Huang CC, Kawamoto M, Johns SJ, Stryke D, Ferrin TE, DeYoung J, Taylor T, Clark AG, Herskowitz I, Giacomini KM, Pharmacogenetics of Membrane Transporters Investigators., Pharmacogenetics. July 1, 2002; 12 (5): 395-405.

Carriers involved in targeting the cytostatic bile acid-cisplatin derivatives cis-diammine-chloro-cholylglycinate-platinum(II) and cis-diammine-bisursodeoxycholate-platinum(II) toward liver cells., Briz O, Serrano MA, Rebollo N, Hagenbuch B, Meier PJ, Koepsell H, Marin JJ., Mol Pharmacol. April 1, 2002; 61 (4): 853-60.

Ventricular choline transport: a role for organic cation transporter 2 expressed in choroid plexus., Sweet DH, Miller DS, Pritchard JB., J Biol Chem. November 9, 2001; 276 (45): 41611-9.

The transport modifier RS1 is localized at the inner side of the plasma membrane and changes membrane capacitance., Valentin M, Kühlkamp T, Wagner K, Krohne G, Arndt P, Baumgarten K, Weber W, Segal A, Veyhl M, Koepsell H., Biochim Biophys Acta. September 29, 2000; 1468 (1-2): 367-80.

Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes., Okuda M, Urakami Y, Saito H, Inui K., Biochim Biophys Acta. March 4, 1999; 1417 (2): 224-31.

A nucleoside-sensitive organic cation transporter in opossum kidney cells., Chen R, Pan BF, Sakurai M, Nelson JA., Am J Physiol. February 1, 1999; 276 (2): F323-8.

Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain., Wu X, Kekuda R, Huang W, Fei YJ, Leibach FH, Chen J, Conway SJ, Ganapathy V., J Biol Chem. December 4, 1998; 273 (49): 32776-86.

Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta., Kekuda R, Prasad PD, Wu X, Wang H, Fei YJ, Leibach FH, Ganapathy V., J Biol Chem. June 26, 1998; 273 (26): 15971-9.

Expression cloning and characterization of a renal organic anion transporter from winter flounder., Wolff NA, Werner A, Burkhardt S, Burckhardt G., FEBS Lett. November 17, 1997; 417 (3): 287-91.

cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2., Okuda M, Saito H, Urakami Y, Takano M, Inui K., Biochem Biophys Res Commun. July 16, 1996; 224 (2): 500-7.

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