Papers associated with kcnh2

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	Inhibition of HERG1 K(+) channels by the novel second-generation antihistamine mizolastine., Taglialatela M, Pannaccione A, Castaldo P, Giorgio G, Annunziato L., Br J Pharmacol. November 1, 2000; 131 (6): 1081-8.
	A structural basis for drug-induced long QT syndrome., Mitcheson JS, Chen J, Lin M, Culberson C, Sanguinetti MC., Proc Natl Acad Sci U S A. October 24, 2000; 97 (22): 12329-33.
	Novel characteristics of a misprocessed mutant HERG channel linked to hereditary long QT syndrome., Ficker E, Thomas D, Viswanathan PC, Dennis AT, Priori SG, Napolitano C, Memmi M, Wible BA, Kaufman ES, Iyengar S, Schwartz PJ, Rudy Y, Brown AM., Am J Physiol Heart Circ Physiol. October 1, 2000; 279 (4): H1748-56.
	Characterization of S818L mutation in HERG C-terminus in LQT2. Modification of activation-deactivation gating properties., Nakajima T, Kurabayashi M, Ohyama Y, Kaneko Y, Furukawa T, Itoh T, Taniguchi Y, Tanaka T, Nakamura Y, Hiraoka M, Nagai R., FEBS Lett. September 15, 2000; 481 (2): 197-203.
	MinK subdomains that mediate modulation of and association with KvLQT1., Tapper AR, George AL., J Gen Physiol. September 1, 2000; 116 (3): 379-90.
	State-dependent barium block of wild-type and inactivation-deficient HERG channels in Xenopus oocytes., Weerapura M, Nattel S, Courtemanche M, Doern D, Ethier N, Hebert T., J Physiol. July 15, 2000; 526 Pt 2 265-78.
	Differential effects of amino-terminal distal and proximal domains in the regulation of human erg K(+) channel gating., Viloria CG, Barros F, Giráldez T, Gómez-Varela D, de la Peña P., Biophys J. July 1, 2000; 79 (1): 231-46.
	Altered gating of HERG potassium channels by cobalt and lanthanum., Sanchez-Chapula JA, Sanguinetti MC., Pflugers Arch. June 1, 2000; 440 (2): 264-74.
	Dynamic control of deactivation gating by a soluble amino-terminal domain in HERG K(+) channels., Wang J, Myers CD, Robertson GA., J Gen Physiol. June 1, 2000; 115 (6): 749-58.
	Redox state dependency of HERGS631C channel pharmacology: relation to C-type inactivation., Ulens C, Tytgat J., FEBS Lett. May 26, 2000; 474 (1): 111-5.
	Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 2nd communication: lack of central nervous system and cardiovascular effects., Kreutner W, Hey JA, Chiu P, Barnett A., Arzneimittelforschung. May 1, 2000; 50 (5): 441-8.
	KChAP as a chaperone for specific K(+) channels., Kuryshev YA, Gudz TI, Brown AM, Wible BA., Am J Physiol Cell Physiol. May 1, 2000; 278 (5): C931-41.
	Blockade of the HERG human cardiac K(+) channel by the antidepressant drug amitriptyline., Jo SH, Youm JB, Lee CO, Lee CO, Earm YE, Ho WK., Br J Pharmacol. April 1, 2000; 129 (7): 1474-80.
	Novel gain-of-function mechanism in K(+) channel-related long-QT syndrome: altered gating and selectivity in the HERG1 N629D mutant., Lees-Miller JP, Duan Y, Teng GQ, Thorstad K, Duff HJ., Circ Res. March 17, 2000; 86 (5): 507-13.
	The distinct HERG missense mutation L564P causes long QT syndrome in one French Canadian family., St-Pierre J, Roy N, Blier L, Plante E, Cote JM, Gilbert M, Chahine M., Can J Cardiol. March 1, 2000; 16 (3): 307-12.
	Trapping of a methanesulfonanilide by closure of the HERG potassium channel activation gate., Mitcheson JS, Chen J, Sanguinetti MC., J Gen Physiol. March 1, 2000; 115 (3): 229-40.
	Molecular determinant of high-affinity dofetilide binding to HERG1 expressed in Xenopus oocytes: involvement of S6 sites., Lees-Miller JP, Duan Y, Teng GQ, Duff HJ., Mol Pharmacol. February 1, 2000; 57 (2): 367-74.
	Ultrafast inactivation causes inward rectification in a voltage-gated K(+) channel from Caenorhabditis elegans., Fleischhauer R, Davis MW, Dzhura I, Neely A, Avery L, Joho RH., J Neurosci. January 15, 2000; 20 (2): 511-20.
	A constitutively open potassium channel formed by KCNQ1 and KCNE3., Schroeder BC, Waldegger S, Fehr S, Bleich M, Warth R, Greger R, Jentsch TJ., Nature. January 13, 2000; 403 (6766): 196-9.
	Analysis of the human KCNH2(HERG) gene: identification and characterization of a novel mutation Y667X associated with long QT syndrome and a non-pathological 9 bp insertion., Paulussen A, Yang P, Pangalos M, Verhasselt P, Marrannes R, Verfaille C, Vandenberk I, Crabbe R, Konings F, Luyten W, Armstrong M., Hum Mutat. January 1, 2000; 15 (5): 483.
	Effects of external acidosis on HERG current expressed in Xenopus oocytes., Terai T, Furukawa T, Katayama Y, Hiraoka M., J Mol Cell Cardiol. January 1, 2000; 32 (1): 11-21.
	Norpropoxyphene-induced cardiotoxicity is associated with changes in ion-selectivity and gating of HERG currents., Ulens C, Daenens P, Tytgat J., Cardiovasc Res. December 1, 1999; 44 (3): 568-78.
	Allosteric effects of mutations in the extracellular S5-P loop on the gating and ion permeation properties of the hERG potassium channel., Dun W, Jiang M, Tseng GN., Pflugers Arch. December 1, 1999; 439 (1-2): 141-9.
	Modulation of the K(+) channels encoded by the human ether-a-gogo-related gene-1 (hERG1) by nitric oxide., Taglialatela M, Pannaccione A, Iossa S, Castaldo P, Annunziato L., Mol Pharmacol. December 1, 1999; 56 (6): 1298-308.
	Use-dependent 'agonist' effect of azimilide on the HERG channel., Jiang M, Dun W, Fan JS, Tseng GN., J Pharmacol Exp Ther. December 1, 1999; 291 (3): 1324-36.
	Voltage-shift of the current activation in HERG S4 mutation (R534C) in LQT2., Nakajima T, Furukawa T, Hirano Y, Tanaka T, Sakurada H, Takahashi T, Nagai R, Itoh T, Katayama Y, Nakamura Y, Hiraoka M., Cardiovasc Res. November 1, 1999; 44 (2): 283-93.
	Mechanism for the effects of extracellular acidification on HERG-channel function., Jiang M, Dun W, Tseng GN., Am J Physiol. October 1, 1999; 277 (4): H1283-92.
	Deletion of protein kinase A phosphorylation sites in the HERG potassium channel inhibits activation shift by protein kinase A., Thomas D, Zhang W, Karle CA, Kathöfer S, Schöls W, Kübler W, Kiehn J., J Biol Chem. September 24, 1999; 274 (39): 27457-62.
	Inactivation gating determines nicotine blockade of human HERG channels., Wang HZ, Shi H, Liao SJ, Wang Z., Am J Physiol. September 1, 1999; 277 (3): H1081-8.
	Inactivation block of the HERG human cardiac K+ channels by RP58866., Wang H, Shi H, Wang Z., Br J Pharmacol. August 1, 1999; 127 (8): 1899-907.
	Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome., Bianchi L, Shen Z, Dennis AT, Priori SG, Napolitano C, Ronchetti E, Bryskin R, Schwartz PJ, Brown AM., Hum Mol Genet. August 1, 1999; 8 (8): 1499-507.
	Pathways of HERG inactivation., Kiehn J, Lacerda AE, Brown AM., Am J Physiol. July 1, 1999; 277 (1): H199-210.
	Proton and zinc effects on HERG currents., Anumonwo JM, Horta J, Delmar M, Taffet SM, Jalife J., Biophys J. July 1, 1999; 77 (1): 282-98.
	Epinastine, a nonsedating histamine H1 receptor antagonist, has a negligible effect on HERG channel., Chachin M, Katayama Y, Yamada M, Horio Y, Ohmura T, Kitagawa H, Uchida S, Kurachi Y., Eur J Pharmacol. June 25, 1999; 374 (3): 457-60.
	Blockade of HERG channels expressed in Xenopus oocytes by external H+., Jo SH, Youm JB, Kim I, Lee CO, Lee CO, Earm YE, Ho WK., Pflugers Arch. June 1, 1999; 438 (1): 23-9.
	Effects of outer mouth mutations on hERG channel function: a comparison with similar mutations in the Shaker channel., Fan JS, Jiang M, Dun W, McDonald TV, Tseng GN., Biophys J. June 1, 1999; 76 (6): 3128-40.
	Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel., Furutani M, Trudeau MC, Hagiwara N, Seki A, Gong Q, Zhou Z, Imamura S, Nagashima H, Kasanuki H, Takao A, Momma K, January CT, Robertson GA, Matsuoka R., Circulation. May 4, 1999; 99 (17): 2290-4.
	Inhibition of HERG channels stably expressed in a mammalian cell line by the antianginal agent perhexiline maleate., Walker BD, Valenzuela SM, Singleton CB, Tie H, Bursill JA, Wyse KR, Qiu MR, Breit SN, Campbell TJ., Br J Pharmacol. May 1, 1999; 127 (1): 243-51.
	MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia., Abbott GW, Sesti F, Splawski I, Buck ME, Lehmann MH, Timothy KW, Keating MT, Goldstein SA., Cell. April 16, 1999; 97 (2): 175-87.
	Functional analysis of a mouse brain Elk-type K+ channel., Trudeau MC, Titus SA, Branchaw JL, Ganetzky B, Robertson GA., J Neurosci. April 15, 1999; 19 (8): 2906-18.
	Long QT syndrome-associated mutations in the Per-Arnt-Sim (PAS) domain of HERG potassium channels accelerate channel deactivation., Chen J, Zou A, Splawski I, Keating MT, Sanguinetti MC., J Biol Chem. April 9, 1999; 274 (15): 10113-8.
	Blockade of HERG channels expressed in Xenopus laevis oocytes by external divalent cations., Ho WK, Kim I, Lee CO, Lee CO, Youm JB, Lee SH, Earm YE., Biophys J. April 1, 1999; 76 (4): 1959-71.
	Inhibitory effects of the class III antiarrhythmic drug amiodarone on cloned HERG potassium channels., Kiehn J, Thomas D, Karle CA, Schöls W, Kübler W., Naunyn Schmiedebergs Arch Pharmacol. March 1, 1999; 359 (3): 212-9.
	Modulation of HERG potassium channels by extracellular magnesium and quinidine., Po SS, Wang DW, Yang IC, Johnson JP, Nie L, Bennett PB., J Cardiovasc Pharmacol. February 1, 1999; 33 (2): 181-5.
	Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes., Sanguinetti MC, Xu QP., J Physiol. February 1, 1999; 514 ( Pt 3) 667-75.
	Effect of verapamil enantiomers and metabolites on cardiac K+ channels expressed in Xenopus oocytes., Waldegger S, Niemeyer G, Mörike K, Wagner CA, Suessbrich H, Busch AE, Lang F, Eichelbaum M., Cell Physiol Biochem. January 1, 1999; 9 (2): 81-9.
	Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain., Morais Cabral JH, Lee A, Cohen SL, Chait BT, Li M, Mackinnon R., Cell. November 25, 1998; 95 (5): 649-55.
	Regulation of deactivation by an amino terminal domain in human ether-à-go-go-related gene potassium channels., Wang J, Trudeau MC, Zappia AM, Robertson GA., J Gen Physiol. November 1, 1998; 112 (5): 637-47.
	HERG potassium channel activation is shifted by phorbol esters via protein kinase A-dependent pathways., Kiehn J, Karle C, Thomas D, Yao X, Brachmann J, Kübler W., J Biol Chem. September 25, 1998; 273 (39): 25285-91.
	Modulation of human erg K+ channel gating by activation of a G protein-coupled receptor and protein kinase C., Barros F, Gomez-Varela D, Viloria CG, Palomero T, Giráldez T, de la Peña P., J Physiol. September 1, 1998; 511 ( Pt 2) 333-46.

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