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Summary Expression Phenotypes Gene Literature (14) GO Terms (3) Nucleotides (85) Proteins (49) Interactants (50) Wiki

Papers associated with cnga3

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Inherited macular degeneration-associated mutations in CNGB3 increase the ligand sensitivity and spontaneous open probability of cone cyclic nucleotide-gated channels., Meighan PC, Peng C, Varnum MD., Front Physiol. June 9, 2015; 6 177.            

Cyclic nucleotide-gated channel subunit glycosylation regulates matrix metalloproteinase-dependent changes in channel gating., Meighan SE, Meighan PC, Rich ED, Brown RL, Varnum MD., Biochemistry. November 19, 2013; 52 (46): 8352-62.

Multiple mechanisms underlying rectification in retinal cyclic nucleotide-gated (CNGA1) channels., Arcangeletti M, Marchesi A, Mazzolini M, Torre V., Physiol Rep. November 1, 2013; 1 (6): e00148.                        

CNGA3 achromatopsia-associated mutation potentiates the phosphoinositide sensitivity of cone photoreceptor CNG channels by altering intersubunit interactions., Dai G, Varnum MD., Am J Physiol Cell Physiol. July 15, 2013; 305 (2): C147-59.

Disease-associated mutations in CNGB3 promote cytotoxicity in photoreceptor-derived cells., Liu C, Sherpa T, Varnum MD., Mol Vis. June 11, 2013; 19 1268-81.              

Two structural components in CNGA3 support regulation of cone CNG channels by phosphoinositides., Dai G, Peng C, Liu C, Varnum MD., J Gen Physiol. April 1, 2013; 141 (4): 413-30.                

Matrix metalloproteinase-9 and -2 enhance the ligand sensitivity of photoreceptor cyclic nucleotide-gated channels., Meighan PC, Meighan SE, Rich ED, Brown RL, Varnum MD., Channels (Austin). January 1, 2012; 6 (3): 181-96.                        

Regulation of human cone cyclic nucleotide-gated channels by endogenous phospholipids and exogenously applied phosphatidylinositol 3,4,5-trisphosphate., Bright SR, Rich ED, Varnum MD., Mol Pharmacol. January 1, 2007; 71 (1): 176-83.

Disease-associated mutations in CNGB3 produce gain of function alterations in cone cyclic nucleotide-gated channels., Bright SR, Brown TE, Varnum MD., Mol Vis. December 19, 2005; 11 1141-50.

Functional consequences of progressive cone dystrophy-associated mutations in the human cone photoreceptor cyclic nucleotide-gated channel CNGA3 subunit., Liu C, Varnum MD., Am J Physiol Cell Physiol. July 1, 2005; 289 (1): C187-98.

Salt bridges and gating in the COOH-terminal region of HCN2 and CNGA1 channels., Craven KB, Zagotta WN., J Gen Physiol. December 1, 2004; 124 (6): 663-77.                      

Subunit configuration of heteromeric cone cyclic nucleotide-gated channels., Peng C, Rich ED, Varnum MD., Neuron. May 13, 2004; 42 (3): 401-10.

Achromatopsia-associated mutation in the human cone photoreceptor cyclic nucleotide-gated channel CNGB3 subunit alters the ligand sensitivity and pore properties of heteromeric channels., Peng C, Rich ED, Varnum MD., J Biol Chem. September 5, 2003; 278 (36): 34533-40.

Functionally important calmodulin-binding sites in both NH2- and COOH-terminal regions of the cone photoreceptor cyclic nucleotide-gated channel CNGB3 subunit., Peng C, Rich ED, Thor CA, Varnum MD., J Biol Chem. July 4, 2003; 278 (27): 24617-23.

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