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Summary Expression Phenotypes Gene Literature (951) GO Terms (5) Nucleotides (271) Proteins (68) Interactants (2348) Wiki
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Papers associated with tbxt



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Cdx1 and Gsc distinctly regulate the transcription of BMP4 target gene ventx3.2 by directly binding to the proximal promoter region in Xenopus gastrulae., Goutam RS, Kumar V, Lee U, Kim J., Mol Cells. March 22, 2024; 100058.                        

Competence for neural crest induction is controlled by hydrostatic pressure through Yap., Alasaadi DN, Alvizi L, Hartmann J, Stillman N, Moghe P, Hiiragi T, Mayor R., Nat Cell Biol. March 18, 2024;                                     

Cell lineage-guided mass spectrometry reveals increased energy metabolism and reactive oxygen species in the vertebrate organizer., Baxi AB, Li J, Quach VM, Pade LR, Moody SA, Nemes P., Proc Natl Acad Sci U S A. February 6, 2024; 121 (6): e2311625121.                  

ZSWIM4 regulates embryonic patterning and BMP signaling by promoting nuclear Smad1 degradation., Wang C, Liu Z, Zeng Y, Zhou L, Long Q, Hassan IU, Zhang Y, Qi X, Cai D, Mao B, Lu G, Sun J, Yao Y, Deng Y, Zhao Q, Feng B, Zhou Q, Chan WY, Zhao H., EMBO Rep. February 1, 2024; 25 (2): 646-671.                                          

Mechanical Tensions Regulate Gene Expression in the Xenopus laevis Axial Tissues., Eroshkin FM, Fefelova EA, Bredov DV, Orlov EE, Kolyupanova NM, Mazur AM, Sokolov AS, Zhigalova NA, Prokhortchouk EB, Nesterenko AM, Zaraisky AG., Int J Mol Sci. January 10, 2024; 25 (2):         

Mitochondrial leak metabolism induces the Spemann-Mangold Organizer via Hif-1α in Xenopus., MacColl Garfinkel A, Mnatsakanyan N, Patel JH, Wills AE, Shteyman A, Smith PJS, Alavian KN, Jonas EA, Khokha MK., Dev Cell. November 20, 2023; 58 (22): 2597-2613.e4.                        

Gene expression in notochord and nuclei pulposi: a study of gene families across the chordate phylum., Raghavan R, Coppola U, Wu Y, Ihewulezi C, Negrón-Piñeiro LJ, Maguire JE, Hong J, Cunningham M, Kim HJ, Albert TJ, Ali AM, Saint-Jeannet JP, Ristoratore F, Dahia CL, Di Gregorio A., BMC Ecol Evol. October 27, 2023; 23 (1): 63.                            

Purine Biosynthesis Pathways Are Required for Myogenesis in Xenopus laevis., Duperray M, Hardet F, Henriet E, Saint-Marc C, Boué-Grabot E, Daignan-Fornier B, Massé K, Pinson B., Cells. September 28, 2023; 12 (19):               

Transmembrane protein 150b attenuates BMP signaling in the Xenopus organizer., Keum BR, Yeo I, Koo Y, Han W, Choi SC, Kim GH, Han JK., J Cell Physiol. August 1, 2023; 238 (8): 1850-1866.                        

The complete dorsal structure is formed from only the blastocoel roof of Xenopus blastula: insight into the gastrulation movement evolutionarily conserved among chordates., Sato Y, Narasaki I, Kunimoto T, Moriyama Y, Hashimoto C., Dev Genes Evol. June 1, 2023; 233 (1): 1-12.                

RAF1 deficiency causes a lethal syndrome that underscores RTK signaling during embryogenesis., Wong S, Tan YX, Loh AYT, Tan KY, Lee H, Aziz Z, Nelson SF, Özkan E, Kayserili H, Escande-Beillard N, Reversade B., EMBO Mol Med. May 8, 2023; 15 (5): e17078.                

OTUD3: A Lys6 and Lys63 specific deubiquitinase in early vertebrate development., Job F, Mai C, Villavicencio-Lorini P, Herfurth J, Neuhaus H, Hoffmann K, Pfirrmann T, Hollemann T., Biochim Biophys Acta Gene Regul Mech. March 1, 2023; 1866 (1): 194901.                

Production and characterization of monoclonal antibodies to Xenopus proteins., Horr B, Kurtz R, Pandey A, Hoffstrom BG, Schock E, LaBonne C, Alfandari D, Alfandari D., Development. February 15, 2023; 150 (4):               

Production and characterization of monoclonal antibodies to xenopus proteins., Horr B, Kurtz R, Pandey A, Hoffstrom BG, Schock E, LaBonne C, Alfandari D, Alfandari D., Development. February 14, 2023;                 

Recognition of H2AK119ub plays an important role in RSF1-regulated early Xenopus development., Parast SM, Yu D, Chen C, Dickinson AJ, Chang C, Wang H., Front Cell Dev Biol. January 1, 2023; 11 1168643.                  

Regulation of gene expression downstream of a novel Fgf/Erk pathway during Xenopus development., Cowell LM, King M, West H, Broadsmith M, Genever P, Pownall ME, Isaacs HV., PLoS One. January 1, 2023; 18 (10): e0286040.                                  

Reconstructing gene regulatory networks of biological function using differential equations of multilayer perceptrons., Mao G, Zeng R, Peng J, Zuo K, Pang Z, Liu J., BMC Bioinformatics. November 24, 2022; 23 (1): 503.            

Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR., Sempou E, Kostiuk V, Zhu J, Cecilia Guerra M, Tyan L, Hwang W, Camacho-Aguilar E, Caplan MJ, Zenisek D, Warmflash A, Owens NDL, Khokha MK., Nat Commun. November 5, 2022; 13 (1): 6681.                                            

Engagement of Foxh1 in chromatin regulation revealed by protein interactome analyses., Zhou JJ, Pham PD, Han H, Wang W, Cho KWY., Dev Growth Differ. August 1, 2022; 64 (6): 297-305.      

Normal Table of Xenopus development: a new graphical resource., Zahn N, James-Zorn C, Ponferrada VG, Adams DS, Grzymkowski J, Buchholz DR, Nascone-Yoder NM, Horb M, Moody SA, Vize PD, Zorn AM., Development. July 15, 2022; 149 (14):                         

HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs., Liang T, Bai J, Zhou W, Lin H, Ma S, Zhu X, Tao Q, Xi Q., Cell Rep. July 12, 2022; 40 (2): 111038.                              

Uncovering the mesendoderm gene regulatory network through multi-omic data integration., Jansen C, Paraiso KD, Zhou JJ, Blitz IL, Fish MB, Charney RM, Cho JS, Yasuoka Y, Sudou N, Bright AR, Wlizla M, Veenstra GJC, Taira M, Zorn AM, Mortazavi A, Cho KWY., Cell Rep. February 15, 2022; 38 (7): 110364.                            

FGF-mediated establishment of left-right asymmetry requires Rab7 function in the dorsal mesoderm in Xenopus., Kreis J, Camuto CM, Elsner CC, Vogel S, Vick P., Front Cell Dev Biol. January 1, 2022; 10 981762.                  

Goosecoid Controls Neuroectoderm Specification via Dual Circuits of Direct Repression and Indirect Stimulation in Xenopus Embryos., Umair Z, Kumar V, Goutam RS, Kumar S, Kumar S, Lee U, Kim J., Mol Cells. October 31, 2021; 44 (10): 723-735.          

The enpp4 ectonucleotidase regulates kidney patterning signalling networks in Xenopus embryos., Massé K, Bhamra S, Paroissin C, Maneta-Peyret L, Boué-Grabot E, Jones EA., Commun Biol. October 7, 2021; 4 (1): 1158.                                

Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects., Galgoczi S, Ruzo A, Markopoulos C, Yoney A, Phan-Everson T, Li S, Haremaki T, Metzger JJ, Etoc F, Brivanlou AH., Development. October 1, 2021; 148 (19):               

Tril dampens Nodal signaling through Pellino2- and Traf6-mediated activation of Nedd4l., Kim HS, Green YS, Xie Y, Christian JL., Proc Natl Acad Sci U S A. September 7, 2021; 118 (36):                       

A systemic cell cycle block impacts stage-specific histone modification profiles during Xenopus embryogenesis., Pokrovsky D, Forné I, Straub T, Imhof A, Rupp RAW., PLoS Biol. September 1, 2021; 19 (9): e3001377.                        

Rab7 is required for mesoderm patterning and gastrulation in Xenopus., Kreis J, Wielath FM, Vick P., Biol Open. July 15, 2021; 10 (7):                                           

BMP signaling is enhanced intracellularly by FHL3 controlling WNT-dependent spatiotemporal emergence of the neural crest., Alkobtawi M, Pla P, Monsoro-Burq AH., Cell Rep. June 22, 2021; 35 (12): 109289.                        

The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus., Zhang F, Zhu X, Wang P, He Q, Huang H, Zheng T, Li Y, Jia H, Xu L, Zhao H, Colozza G, Tao Q, De Robertis EM, Ding Y., Proc Natl Acad Sci U S A. May 18, 2021; 118 (20):           

Kindlin2 regulates neural crest specification via integrin-independent regulation of the FGF signaling pathway., Wang H, Wang C, Wang C, Wang C, Long Q, Zhang Y, Wang M, Liu J, Qi X, Cai D, Lu G, Sun J, Yao YG, Chan WY, Chan WY, Deng Y, Zhao H., Development. May 15, 2021; 148 (10):                                           

Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates., Bright AR, van Genesen S, Li Q, Grasso A, Frölich S, van der Sande M, van Heeringen SJ, Veenstra GJC., EMBO J. May 3, 2021; 40 (9): e104913.                        

A temporally resolved transcriptome for developing "Keller" explants of the Xenopus laevis dorsal marginal zone., Kakebeen AD, Huebner RJ, Shindo A, Kwon K, Kwon T, Wills AE, Wallingford JB., Dev Dyn. May 1, 2021; 250 (5): 717-731.              

Furry is required for cell movements during gastrulation and functionally interacts with NDR1., Cervino AS, Moretti B, Stuckenholz C, Grecco HE, Davidson LA, Davidson LA, Cirio MC., Sci Rep. March 23, 2021; 11 (1): 6607.                                  

Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage., Castro Colabianchi AM, Tavella MB, Boyadjián López LE, Rubinstein M, Franchini LF, López SL., Biol Open. February 25, 2021; 10 (2):                 

Modeling endoderm development and disease in Xenopus., Edwards NA, Zorn AM., Curr Top Dev Biol. January 1, 2021; 145 61-90.

Evolution of Somite Compartmentalization: A View From Xenopus., Della Gaspera B, Weill L, Chanoine C., Front Cell Dev Biol. January 1, 2021; 9 790847.                  

Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis., Lee H, Lee H, Ismail T, Kim Y, Chae S, Ryu HY, Lee DS, Kwon TK, Park TJ, Kwon T, Lee HS, Lee HS., Antioxidants (Basel). December 12, 2020; 9 (12):               

Generation of a FOXH1 homozygous knockout human embryonic stem cell line by CRISPR/Cas9 system., Zhang T, Huang W, Xue X., Stem Cell Res. December 10, 2020; 50 102121.  

Identification and characterization of a fibroblast growth factor gene in the planarian Dugesia japonica., Auwal MA, Kashima M, Nishimura O, Hosoda K, Motoishi M, Kamimura A, Okumura A, Agata K, Umesono Y., Dev Growth Differ. December 1, 2020; 62 (9): 527-539.

Dusp1 modulates activin/smad2 mediated germ layer specification via FGF signal inhibition in Xenopus embryos., Umair Z, Kumar S, Rafiq K, Kumar V, Reman ZU, Lee SH, Kim S, Lee JY, Lee U, Kim J., Anim Cells Syst (Seoul). November 27, 2020; 24 (6): 359-370.            

Foxd4l1.1 negatively regulates transcription of neural repressor ventx1.1 during neuroectoderm formation in Xenopus embryos., Kumar S, Kumar S, Umair Z, Kumar V, Kumar S, Lee U, Kim J., Sci Rep. October 8, 2020; 10 (1): 16780.            

TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X., Elife. September 14, 2020; 9                                                                                           

Pinhead signaling regulates mesoderm heterogeneity via the FGF receptor-dependent pathway., Ossipova O, Itoh K, Radu A, Ezan J, Sokol SY., Development. September 11, 2020; 147 (17):                 

Brachyury in the gastrula of basal vertebrates., Bruce AEE, Winklbauer R., Mech Dev. September 1, 2020; 163 103625.                  

Chromatin accessibility and histone acetylation in the regulation of competence in early development., Esmaeili M, Blythe SA, Tobias JW, Zhang K, Yang J, Klein PS., Dev Biol. June 1, 2020; 462 (1): 20-35.                

Tbx2 mediates dorsal patterning and germ layer suppression through inhibition of BMP/GDF and Activin/Nodal signaling., Reich S, Kayastha P, Teegala S, Weinstein DC., BMC Mol Cell Biol. May 28, 2020; 21 (1): 39.              

Rspo2 antagonizes FGF signaling during vertebrate mesoderm formation and patterning., Reis AH, Sokol SY., Development. May 27, 2020; 147 (10):                   

Heparan sulfate proteoglycans regulate BMP signalling during neural crest induction., Pegge J, Tatsinkam AJ, Rider CC, Bell E., Dev Biol. April 15, 2020; 460 (2): 108-114.        

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