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Summary Expression Phenotypes Gene Literature (76) GO Terms (5) Nucleotides (69) Proteins (42) Interactants (250) Wiki
XB-GENEPAGE-953894

Papers associated with cyp19a1



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Environmentally relevant concentrations of aqueous atorvastatin produce alterations in cholesterol biosynthesis and gene expression patterns in Xenopus laevis., Johnson JR, Griffitt RJ., Aquat Toxicol. April 1, 2024; 269 106856.

Impaired spermatogenesis and associated endocrine effects of azole fungicides in peripubertal Xenopus tropicalis., Svanholm S, Brouard V, Roza M, Marini D, Karlsson O, Berg C., Ecotoxicol Environ Saf. January 15, 2024; 270 115876.                  

Bisphenol B disrupts testis differentiation partly via the estrogen receptor-mediated pathway and subsequently causes testicular dysgenesis in Xenopus laevis., Li HM, Li YY, Zhang YC, Li JB, Xu HM, Xiong YM, Qin ZF., Ecotoxicol Environ Saf. May 1, 2022; 236 113453.              

Developmental reproductive toxicity and endocrine activity of propiconazole in the Xenopus tropicalis model., Svanholm S, Säfholm M, Brande-Lavridsen N, Larsson E, Berg C., Sci Total Environ. January 20, 2021; 753 141940.                        

Transcriptomic analysis identifies early cellular and molecular events by which estrogen disrupts testis differentiation and causes feminization in Xenopus laevis., Li Y, Shen Y, Li J, Cai M, Qin Z., Aquat Toxicol. September 1, 2020; 226 105557.

DNA methylation dynamics underlie metamorphic gene regulation programs in Xenopus tadpole brain., Kyono Y, Raj S, Sifuentes CJ, Buisine N, Sachs L, Denver RJ., Dev Biol. June 15, 2020; 462 (2): 180-196.                                                    

Polybrominated Diphenylether (DE-71) Exposure Skews Phenotypic Sex Ratio, and Alters Steroid Hormone Levels and Steroidogenic Enzyme Activities in Juvenile Silurana tropicalis., Fort DJ, Mathis M, Fort C, Fort TD, Guiney PD, Weeks JA., Toxicol Sci. November 1, 2019; 172 (1): 63-74.

Effect of perfluorooctanesulfonate exposure on steroid hormone levels and steroidogenic enzyme activities in juvenile Silurana tropicalis., Fort DJ, Mathis MB, Fort CE, Fort HM, Fort TD, Guiney PD, Weeks JA., J Appl Toxicol. July 1, 2019; 39 (7): 1066-1078.

The Xenopus tropicalis Model for Studies of Developmental and Reproductive Toxicity., Berg C., Methods Mol Biol. January 1, 2019; 1965 173-186.

Thyroid hormones and androgens differentially regulate gene expression in testes and ovaries of sexually mature Silurana tropicalis., Campbell DEK, Langlois VS., Gen Comp Endocrinol. October 1, 2018; 267 172-182.            

Exposure to an anti-androgenic herbicide negatively impacts reproductive physiology and fertility in Xenopus tropicalis., Orton F, Säfholm M, Jansson E, Carlsson Y, Eriksson A, Fick J, Uren Webster T, McMillan T, Leishman M, Verbruggen B, Economou T, Tyler CR, Berg C., Sci Rep. June 14, 2018; 8 (1): 9124.          

Transcriptome analysis identifies genes involved in sex determination and development of Xenopus laevis gonads., Piprek RP, Damulewicz M, Kloc M, Kubiak JZ., Differentiation. January 1, 2018; 100 46-56.                          

Endocrine disruption by environmental gestagens in amphibians - A short review supported by new in vitro data using gonads of Xenopus laevis., Ziková A, Lorenz C, Hoffmann F, Kleiner W, Lutz I, Stöck M, Kloas W., Chemosphere. August 1, 2017; 181 74-82.

Transcriptomic and macroevolutionary evidence for phenotypic uncoupling between frog life history phases., Wollenberg Valero KC, Garcia-Porta J, Rodríguez A, Arias M, Shah A, Randrianiaina RD, Brown JL, Glaw F, Amat F, Künzel S, Metzler D, Isokpehi RD, Vences M., Nat Commun. May 15, 2017; 8 15213.      

Masculinization-Related Genes and Cell-Mass Structures During Early Gonadal Differentiation in the African Clawed Frog Xenopus laevis., Wada M, Fujitani K, Tamura K, Mawaribuchi S, Kamata Y, Takamatsu N, Ito M., Zoolog Sci. April 1, 2017; 34 (2): 105-111.

Boric Acid Is Reproductively Toxic to Adult Xenopus laevis, but Not Endocrine Active., Fort DJ, Fort TD, Mathis MB, Ball RW., Toxicol Sci. November 1, 2016; 154 (1): 16-26.

Lethal and sublethal effects of phthalate diesters in Silurana tropicalis larvae., Mathieu-Denoncourt J, Martyniuk CJ, Loughery JR, Yargeau V, de Solla SR, Langlois VS., Environ Toxicol Chem. October 1, 2016; 35 (10): 2511-2522.

Life cycle exposure of the frog Silurana tropicalis to arsenate: Steroid- and thyroid hormone-related genes are differently altered throughout development., Gibson LA, Koch I, Reimer KJ, Cullen WR, Langlois VS., Gen Comp Endocrinol. August 1, 2016; 234 133-41.        

Metabolic and immune impairments induced by the endocrine disruptors benzo[a]pyrene and triclosan in Xenopus tropicalis., Regnault C, Willison J, Veyrenc S, Airieau A, Méresse P, Fortier M, Fournier M, Brousseau P, Raveton M, Reynaud S., Chemosphere. July 1, 2016; 155 519-527.

Sex-dependent expression of anti-Müllerian hormone (amh) and amh receptor 2 during sex organ differentiation and characterization of the Müllerian duct development in Xenopus tropicalis., Jansson E, Mattsson A, Goldstone J, Berg C., Gen Comp Endocrinol. April 1, 2016; 229 132-44.

Molecular and histological endpoints for developmental reproductive toxicity in Xenopus tropicalis: Levonorgestrel perturbs anti-Müllerian hormone and progesterone receptor expression., Säfholm M, Jansson E, Fick J, Berg C., Comp Biochem Physiol C Toxicol Pharmacol. January 1, 2016; 181-182 9-18.

Tebuconazole disrupts steroidogenesis in Xenopus laevis., Poulsen R, Luong X, Hansen M, Styrishave B, Hayes T., Aquat Toxicol. November 1, 2015; 168 28-37.

Expression of the cyp19a1 gene in the adult brain of Xenopus is neuronal and not sexually dimorphic., Coumailleau P, Kah O., Gen Comp Endocrinol. September 15, 2015; 221 203-12.        

Aromatase, estrogen receptors and brain development in fish and amphibians., Coumailleau P, Pellegrini E, Adrio F, Diotel N, Cano-Nicolau J, Nasri A, Vaillant C, Kah O., Biochim Biophys Acta. February 1, 2015; 1849 (2): 152-62.

TRPV4 associates environmental temperature and sex determination in the American alligator., Yatsu R, Miyagawa S, Kohno S, Saito S, Lowers RH, Ogino Y, Fukuta N, Katsu Y, Ohta Y, Tominaga M, Guillette LJ, Iguchi T., Sci Rep. January 12, 2015; 5 18581.        

Cell-mass structures expressing the aromatase gene Cyp19a1 lead to ovarian cavities in Xenopus laevis., Mawaribuchi S, Ikeda N, Fujitani K, Ito Y, Onuma Y, Komiya T, Takamatsu N, Ito M., Endocrinology. October 1, 2014; 155 (10): 3996-4005.  

Early expression of aromatase and the membrane estrogen receptor GPER in neuromasts reveals a role for estrogens in the development of the frog lateral line system., Hamilton CK, Navarro-Martin L, Neufeld M, Basak A, Trudeau VL., Gen Comp Endocrinol. September 1, 2014; 205 242-50.                    

Cyp19a1 (aromatase) expression in the Xenopus brain at different developmental stages., Coumailleau P, Kah O., J Neuroendocrinol. April 1, 2014; .          

Expression profile of the aromatase enzyme in the Xenopus brain and localization of estradiol and estrogen receptors in each tissue., Iwabuchi J, Koshimizu K, Nakagawa T., Gen Comp Endocrinol. December 1, 2013; 194 286-94.            

Effects of perfluorooctanesulfonate and perfluorobutanesulfonate on the growth and sexual development of Xenopus laevis., Lou QQ, Zhang YF, Zhang YF, Zhou Z, Shi YL, Ge YN, Ren DK, Xu HM, Zhao YX, Wei WJ, Qin ZF., Ecotoxicology. September 1, 2013; 22 (7): 1133-44.

Developmental exposure to fluoxetine modulates the serotonin system in hypothalamus., Berg C, Backström T, Winberg S, Lindberg R, Brandt I., PLoS One. January 1, 2013; 8 (1): e55053.  

Brain-specific promoter/exon I.f of the cyp19a1 (aromatase) gene in Xenopus laevis., Nakagawa T, Iwabuchi J., J Steroid Biochem Mol Biol. November 1, 2012; 132 (3-5): 247-55.

An amphibian model for studies of developmental reproductive toxicity., Berg C., Methods Mol Biol. January 1, 2012; 889 73-83.

Developmental profiles and thyroid hormone regulation of brain transcripts in frogs: a species comparison with emphasis on Physalaemus pustulosus., Duarte-Guterman P, Ryan MJ, Hogan NS, Trudeau VL., Brain Behav Evol. January 1, 2012; 79 (2): 98-112.

The synthetic gestagen Levonorgestrel disrupts sexual development in Xenopus laevis by affecting gene expression of pituitary gonadotropins and gonadal steroidogenic enzymes., Lorenz C, Contardo-Jara V, Trubiroha A, Krüger A, Viehmann V, Wiegand C, Pflugmacher S, Nützmann G, Lutz I, Kloas W., Toxicol Sci. December 1, 2011; 124 (2): 311-9.

Characterization of cAMP response element-like sequence in gonadal specific aromatase promoter sequence of Xenopus embryos., Onoe M, Iwabuchi J, Nagasawa K, Tajima M, Ouwashi M, Dan K, Miyata S., Zoolog Sci. November 1, 2011; 28 (11): 828-33.

Aromatase expression in Xenopus oocytes: a three cell-type model for the ovarian estradiol synthesis., Gohin M, Bodinier P, Fostier A, Bobe J, Chesnel F., J Mol Endocrinol. September 7, 2011; 47 (2): 241-50.

Expression profiles of reproduction- and thyroid hormone-related transcripts in the brains of chemically-induced intersex frogs., Langlois VS, Duarte-Guterman P, Trudeau VL., Sex Dev. January 1, 2011; 5 (1): 26-32.

Mate calling behavior of male South African clawed frogs (Xenopus laevis) is suppressed by the antiandrogenic endocrine disrupting compound flutamide., Behrends T, Urbatzka R, Krackow S, Elepfandt A, Kloas W., Gen Comp Endocrinol. September 1, 2010; 168 (2): 269-74.

Aqueous leaf extracts display endocrine activities in vitro and disrupt sexual differentiation of male Xenopus laevis tadpoles in vivo., Hermelink B, Urbatzka R, Wiegand C, Pflugmacher S, Lutz I, Kloas W., Gen Comp Endocrinol. September 1, 2010; 168 (2): 245-55.

Aromatase mRNA expression in the brain of adult Xenopus laevis exposed to Lambro river water and endocrine disrupting compounds., Massari A, Urbatzka R, Cevasco A, Canesi L, Lanza C, Scarabelli L, Kloas W, Mandich A., Gen Comp Endocrinol. September 1, 2010; 168 (2): 262-8.

Regulation of thyroid hormone-, oestrogen- and androgen-related genes by triiodothyronine in the brain of Silurana tropicalis., Duarte-Guterman P, Trudeau VL., J Neuroendocrinol. September 1, 2010; 22 (9): 1023-31.        

Fadrozole and finasteride exposures modulate sex steroid- and thyroid hormone-related gene expression in Silurana (Xenopus) tropicalis early larval development., Langlois VS, Duarte-Guterman P, Ing S, Pauli BD, Cooke GM, Trudeau VL., Gen Comp Endocrinol. April 1, 2010; 166 (2): 417-27.

Expression and T3 regulation of thyroid hormone- and sex steroid-related genes during Silurana (Xenopus) tropicalis early development., Duarte-Guterman P, Langlois VS, Pauli BD, Trudeau VL., Gen Comp Endocrinol. April 1, 2010; 166 (2): 428-35.          

Atrazine induces complete feminization and chemical castration in male African clawed frogs (Xenopus laevis)., Hayes TB, Khoury V, Narayan A, Nazir M, Park A, Brown T, Adame L, Chan E, Buchholz D, Stueve T, Gallipeau S., Proc Natl Acad Sci U S A. March 9, 2010; 107 (10): 4612-7.            

Comparative transcriptomic analysis of follicle-enclosed oocyte maturational and developmental competence acquisition in two non-mammalian vertebrates., Gohin M, Bobe J, Chesnel F., BMC Genomics. January 8, 2010; 11 18.                    

Characterization of an activating transcription factor 4 gene containing a consensus phosphorylation site for PKA in the gonads of Xenopus embryos., Komatsuzaki E, Kitamura T, Murayama I, Saigo Y, Ojima K, Akatsuka N, Iwabuchi J, Miyata S., Zoolog Sci. January 1, 2010; 27 (1): 19-23.

Exposure of Xenopus laevis tadpoles to finasteride, an inhibitor of 5-alpha reductase activity, impairs spermatogenesis and alters hypophyseal feedback mechanisms., Urbatzka R, Watermann B, Lutz I, Kloas W., J Mol Endocrinol. November 1, 2009; 43 (5): 209-19.

Sox3: a transcription factor for Cyp19 expression in the frog Rana rugosa., Oshima Y, Naruse K, Nakamura Y, Nakamura M., Gene. September 15, 2009; 445 (1-2): 38-48.

Does atrazine affect larval development and sexual differentiation of South African clawed frogs?, Kloas W, Lutz I, Urbatzka R, Springer T, Krueger H, Wolf J, Holden L, Hosmer A., Ann N Y Acad Sci. April 1, 2009; 1163 437-40.

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