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Summary Expression Phenotypes Gene Literature (82) GO Terms (10) Nucleotides (60) Proteins (36) Interactants (422) Wiki
XB-GENEPAGE-483330

Papers associated with pdx1



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XlHbox 8: a novel Xenopus homeo protein restricted to a narrow band of endoderm., Wright CV, Schnegelsberg P, De Robertis EM., Development. April 1, 1989; 105 (4): 787-94.          

IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene., Miller CP, McGehee RE, Habener JF., EMBO J. March 1, 1994; 13 (5): 1145-56.

XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor., Peshavaria M, Gamer L, Henderson E, Teitelman G, Wright CV, Stein R., Mol Endocrinol. June 1, 1994; 8 (6): 806-16.

Cloning of rat homeobox genes., Sakoyama Y, Mizuta I, Ogasawara N, Yoshikawa H., Biochem Genet. October 1, 1994; 32 (9-10): 351-60.

Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny., Guz Y, Montminy MR, Stein R, Leonard J, Gamer LW, Wright CV, Teitelman G., Development. January 1, 1995; 121 (1): 11-8.

Autonomous endodermal determination in Xenopus: regulation of expression of the pancreatic gene XlHbox 8., Gamer LW, Wright CV., Dev Biol. September 1, 1995; 171 (1): 240-51.                

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum., Offield MF, Jetton TL, Labosky PA, Ray M, Stein RW, Magnuson MA, Hogan BL, Wright CV., Development. March 1, 1996; 122 (3): 983-95.

A vegetally localized T-box transcription factor in Xenopus eggs specifies mesoderm and endoderm and is essential for embryonic mesoderm formation., Horb ME, Thomsen GH., Development. May 1, 1997; 124 (9): 1689-98.                    

Functional characterization of the transactivation properties of the PDX-1 homeodomain protein., Peshavaria M, Henderson E, Sharma A, Wright CV, Stein R., Mol Cell Biol. July 1, 1997; 17 (7): 3987-96.

Mutant Vg1 ligands disrupt endoderm and mesoderm formation in Xenopus embryos., Joseph EM, Melton DA., Development. July 1, 1998; 125 (14): 2677-85.            

A role for the vegetally expressed Xenopus gene Mix.1 in endoderm formation and in the restriction of mesoderm to the marginal zone., Lemaire P, Darras S, Caillol D, Kodjabachian L., Development. July 1, 1998; 125 (13): 2371-80.

Development of the gut in Xenopus laevis., Chalmers AD, Slack JM., Dev Dyn. August 1, 1998; 212 (4): 509-21.    

The role of maternal VegT in establishing the primary germ layers in Xenopus embryos., Zhang J, Houston DW, King ML, Payne C, Wylie C, Heasman J., Cell. August 21, 1998; 94 (4): 515-24.                

An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2)., Swift GH, Liu Y, Rose SD, Bischof LJ, Steelman S, Buchberg AM, Wright CV, MacDonald RJ., Mol Cell Biol. September 1, 1998; 18 (9): 5109-20.

Cloning of Mix-related homeodomain proteins using fast retrieval of gel shift activities, (FROGS), a technique for the isolation of DNA-binding proteins., Mead PE, Zhou Y, Lustig KD, Huber TL, Kirschner MW, Zon LI., Proc Natl Acad Sci U S A. September 15, 1998; 95 (19): 11251-6.              

A possible role for the high mobility group box transcription factor Tcf-4 in vertebrate gut epithelial cell differentiation., Lee YJ, Swencki B, Shoichet S, Shivdasani RA., J Biol Chem. January 15, 1999; 274 (3): 1566-72.  

Rearranging gastrulation in the name of yolk: evolution of gastrulation in yolk-rich amniote eggs., Arendt D, Nübler-Jung K., Mech Dev. March 1, 1999; 81 (1-2): 3-22.

Xenopus nodal-related signaling is essential for mesendodermal patterning during early embryogenesis., Osada SI, Wright CV., Development. June 1, 1999; 126 (14): 3229-40.                

Expression of the highly conserved RNA binding protein KOC in embryogenesis., Mueller-Pillasch F, Pohl B, Wilda M, Lacher U, Beil M, Wallrapp C, Hameister H, Knöchel W, Adler G, Gress TM., Mech Dev. October 1, 1999; 88 (1): 95-9.  

The Xenopus tadpole gut: fate maps and morphogenetic movements., Chalmers AD, Slack JM., Development. January 1, 2000; 127 (2): 381-92.                  

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas., Gradwohl G, Dierich A, LeMeur M, Guillemot F., Proc Natl Acad Sci U S A. February 15, 2000; 97 (4): 1607-11.

In vitro organogenesis of pancreas in Xenopus laevis dorsal lips treated with retinoic acid., Moriya N, Komazaki S, Asashima M., Dev Growth Differ. April 1, 2000; 42 (2): 175-85.      

Action of the Caenorhabditis elegans GATA factor END-1 in Xenopus suggests that similar mechanisms initiate endoderm development in ecdysozoa and vertebrates., Shoichet SA, Malik TH, Rothman JH, Shivdasani RA., Proc Natl Acad Sci U S A. April 11, 2000; 97 (8): 4076-81.          

Development of the pancreas in Xenopus laevis., Kelly OG, Melton DA., Dev Dyn. August 1, 2000; 218 (4): 615-27.                  

A role for GATA5 in Xenopus endoderm specification., Weber H, Symes CE, Walmsley ME, Rodaway AR, Patient RK., Development. October 1, 2000; 127 (20): 4345-60.                  

Downregulation of Hedgehog signaling is required for organogenesis of the small intestine in Xenopus., Zhang J, Rosenthal A, de Sauvage FJ, Shivdasani RA., Dev Biol. January 1, 2001; 229 (1): 188-202.                  

The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development., Reissmann E, Jörnvall H, Blokzijl A, Andersson O, Chang C, Minchiotti G, Persico MG, Ibáñez CF, Brivanlou AH., Genes Dev. August 1, 2001; 15 (15): 2010-22.                

Endoderm specification and differentiation in Xenopus embryos., Horb ME, Slack JM., Dev Biol. August 15, 2001; 236 (2): 330-43.                

Cloning and characterization of the T-box gene Tbx6 in Xenopus laevis., Uchiyama H, Kobayashi T, Yamashita A, Ohno S, Yabe S., Dev Growth Differ. December 1, 2001; 43 (6): 657-69.            

Endoderm is required for vascular endothelial tube formation, but not for angioblast specification., Vokes SA, Krieg PA., Development. February 1, 2002; 129 (3): 775-85.            

Conserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6., Samaras SE, Cissell MA, Gerrish K, Wright CV, Gannon M, Stein R., Mol Cell Biol. July 1, 2002; 22 (13): 4702-13.

Repression of organizer genes in dorsal and ventral Xenopus cells mediated by maternal XTcf3., Houston DW, Kofron M, Resnik E, Langland R, Destree O, Wylie C, Heasman J., Development. September 1, 2002; 129 (17): 4015-25.          

Experimental conversion of liver to pancreas., Horb ME, Shen CN, Tosh D, Slack JM., Curr Biol. January 21, 2003; 13 (2): 105-15.    

Cell-autonomous and signal-dependent expression of liver and intestine marker genes in pluripotent precursor cells from Xenopus embryos., Chen Y, Chen Y, Jürgens K, Hollemann T, Claussen M, Ramadori G, Pieler T., Mech Dev. March 1, 2003; 120 (3): 277-88.                      

Screening for novel pancreatic genes from in vitro-induced pancreas in Xenopus., Sogame A, Hayata T, Asashima M., Dev Growth Differ. April 1, 2003; 45 (2): 143-52.                  

Sox9, a novel pancreatic marker in Xenopus., Lee YH, Lee YH, Saint-Jeannet JP., Int J Dev Biol. September 1, 2003; 47 (6): 459-62.      

Pancreatic protein disulfide isomerase (XPDIp) is an early marker for the exocrine lineage of the developing pancreas in Xenopus laevis embryos., Afelik S, Chen Y, Pieler T., Gene Expr Patterns. January 1, 2004; 4 (1): 71-6.    

Differential regulation of islet-specific glucose-6-phosphatase catalytic subunit-related protein gene transcription by Pax-6 and Pdx-1., Martin CC, Oeser JK, O'Brien RM., J Biol Chem. August 13, 2004; 279 (33): 34277-89.

TGF-beta signaling potentiates differentiation of embryonic stem cells to Pdx-1 expressing endodermal cells., Shiraki N, Lai CJ, Hishikari Y, Kume S., Genes Cells. June 1, 2005; 10 (6): 503-16.

NeuroD1 in the endocrine pancreas: localization and dual function as an activator and repressor., Itkin-Ansari P, Marcora E, Geron I, Tyrberg B, Demeterco C, Hao E, Padilla C, Ratineau C, Leiter A, Lee JE, Lee JE, Levine F., Dev Dyn. July 1, 2005; 233 (3): 946-53.

Wnt5 signaling in vertebrate pancreas development., Kim HJ, Schleiffarth JR, Jessurun J, Sumanas S, Petryk A, Lin S, Ekker SC., BMC Biol. October 24, 2005; 3 23.                    

GATA factors as key regulatory molecules in the development of Drosophila endoderm., Murakami R, Okumura T, Uchiyama H., Dev Growth Differ. December 1, 2005; 47 (9): 581-9.  

The RNA-binding protein, Vg1RBP, is required for pancreatic fate specification., Spagnoli FM, Brivanlou AH., Dev Biol. April 15, 2006; 292 (2): 442-56.                      

Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue., Afelik S, Chen Y, Pieler T., Genes Dev. June 1, 2006; 20 (11): 1441-6.                        

Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum and liver to pancreas., Jarikji ZH, Vanamala S, Beck CW, Wright CV, Leach SD, Horb ME., Dev Biol. April 15, 2007; 304 (2): 786-99.                

Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development., McLin VA, Rankin SA, Zorn AM., Development. June 1, 2007; 134 (12): 2207-17.            

Retinoic acid-mediated patterning of the pre-pancreatic endoderm in Xenopus operates via direct and indirect mechanisms., Pan FC, Chen Y, Chen Y, Bayha E, Pieler T., Mech Dev. August 1, 2007; 124 (7-8): 518-31.      

The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm., Spagnoli FM, Brivanlou AH., Development. February 1, 2008; 135 (3): 451-61.                                                    

Remodeling the exocrine pancreas at metamorphosis in Xenopus laevis., Mukhi S, Mao J, Brown DD., Proc Natl Acad Sci U S A. July 1, 2008; 105 (26): 8962-7.              

Promoting ectopic pancreatic fates: pancreas development and future diabetes therapies., Pearl EJ, Horb ME., Clin Genet. October 1, 2008; 74 (4): 316-24.    

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