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Summary Expression Phenotypes Gene Literature (86) GO Terms (10) Nucleotides (419) Proteins (51) Interactants (322) Wiki
XB-GENEPAGE-1014887

Papers associated with cdt1



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Novel angiotensin II antagonists distinguish amphibian from mammalian angiotensin II receptors expressed in Xenopus laevis oocytes., Ji H, Sandberg K, Catt KJ., Mol Pharmacol. February 1, 1991; 39 (2): 120-3.

Amphibian myocardial angiotensin II receptors are distinct from mammalian AT1 and AT2 receptor subtypes., Sandberg K, Ji H, Millan MA, Catt KJ., FEBS Lett. June 24, 1991; 284 (2): 281-4.

Molecular cloning, sequencing and functional expression of an amphibian angiotensin II receptor., Ji H, Sandberg K, Zhang Y, Catt KJ., Biochem Biophys Res Commun. July 30, 1993; 194 (2): 756-62.

Characterization of a functional angiotensin II receptor in Xenopus laevis heart., Aiyar N, Baker E, Pullen M, Nuthulaganti P, Bergsma DJ, Kumar C, Nambi P., Pharmacology. April 1, 1994; 48 (4): 242-9.

XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis., Maiorano D, Moreau J, Méchali M., Nature. April 6, 2000; 404 (6778): 622-5.

Cell cycle. License withheld--geminin blocks DNA replication., Lygerou Z, Nurse P., Science. December 22, 2000; 290 (5500): 2271-3.

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1., Wohlschlegel JA, Dwyer BT, Dhar SK, Cvetic C, Walter JC, Dutta A., Science. December 22, 2000; 290 (5500): 2309-12.

Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins., Gillespie PJ, Li A, Blow JJ., BMC Biochem. January 1, 2001; 2 15.                

Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin., Tada S, Li A, Maiorano D, Méchali M, Blow JJ., Nat Cell Biol. February 1, 2001; 3 (2): 107-13.

The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis., Quinn LM, Herr A, McGarry TJ, Richardson H., Genes Dev. October 15, 2001; 15 (20): 2741-54.    

mei-41 and bub1 block mitosis at two distinct steps in response to incomplete DNA replication in Drosophila embryos., Garner M, van Kreeveld S, Su TT., Curr Biol. October 16, 2001; 11 (20): 1595-9.

The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase., Nishitani H, Taraviras S, Lygerou Z, Nishimoto T., J Biol Chem. November 30, 2001; 276 (48): 44905-11.

Mammalian nuclei become licensed for DNA replication during late telophase., Dimitrova DS, Prokhorova TA, Blow JJ, Todorov IT, Gilbert DM., J Cell Sci. January 1, 2002; 115 (Pt 1): 51-9.

Oncogenic potential of the DNA replication licensing protein CDT1., Arentson E, Faloon P, Seo J, Moon E, Studts JM, Fremont DH, Choi K., Oncogene. February 14, 2002; 21 (8): 1150-8.

Essential role of human CDT1 in DNA replication and chromatin licensing., Rialland M, Sola F, Santocanale C., J Cell Sci. April 1, 2002; 115 (Pt 7): 1435-40.

Identification of Tah11/Sid2 as the ortholog of the replication licensing factor Cdt1 in Saccharomyces cerevisiae., Devault A, Vallen EA, Yuan T, Green S, Bensimon A, Schwob E., Curr Biol. April 16, 2002; 12 (8): 689-94.

Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import., Hodgson B, Li A, Tada S, Blow JJ., Curr Biol. April 16, 2002; 12 (8): 678-83.

Control of DNA replication licensing in a cell cycle., Nishitani H, Lygerou Z., Genes Cells. June 1, 2002; 7 (6): 523-34.        

MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts., Edwards MC, Tutter AV, Cvetic C, Gilbert CH, Prokhorova TA, Walter JC., J Biol Chem. September 6, 2002; 277 (36): 33049-57.

Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex., Chou DM, Petersen P, Walter JC, Walter G., J Biol Chem. October 25, 2002; 277 (43): 40520-7.

The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication., Van Hatten RA, Tutter AV, Holway AH, Khederian AM, Walter JC, Michael WM., J Cell Biol. November 25, 2002; 159 (4): 541-7.          

Direct interaction of geminin and Six3 in eye development., Del Bene F, Tessmar-Raible K, Wittbrodt J., Nature. February 19, 2004; 427 (6976): 745-9.

Cell cycle regulation of the licensing activity of Cdt1 in Xenopus laevis., Maiorano D, Rul W, Méchali M., Exp Cell Res. April 15, 2004; 295 (1): 138-49.

The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation., Oehlmann M, Score AJ, Blow JJ., J Cell Biol. April 26, 2004; 165 (2): 181-90.                  

A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication., Jares P, Luciani MG, Blow JJ., BMC Mol Biol. June 28, 2004; 5 5.          

A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition., Saxena S, Yuan P, Dhar SK, Senga T, Takeda D, Robinson H, Kornbluth S, Swaminathan K, Dutta A., Mol Cell. July 23, 2004; 15 (2): 245-58.

Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis., Ballabeni A, Melixetian M, Zamponi R, Masiero L, Marinoni F, Helin K., EMBO J. August 4, 2004; 23 (15): 3122-32.

Structural basis for inhibition of the replication licensing factor Cdt1 by geminin., Lee C, Lee C, Hong B, Choi JM, Kim Y, Watanabe S, Ishimi Y, Enomoto T, Tada S, Kim Y, Cho Y., Nature. August 19, 2004; 430 (7002): 913-7.

A hypophosphorylated form of RPA34 is a specific component of pre-replication centers., Françon P, Lemaître JM, Dreyer C, Maiorano D, Cuvier O, Méchali M., J Cell Sci. October 1, 2004; 117 (Pt 21): 4909-20.                      

Recruitment of Xenopus Scc2 and cohesin to chromatin requires the pre-replication complex., Takahashi TS, Yiu P, Chou MF, Gygi S, Walter JC., Nat Cell Biol. October 1, 2004; 6 (10): 991-6.

Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity., Benjamin JM, Torke SJ, Demeler B, McGarry TJ., J Biol Chem. October 29, 2004; 279 (44): 45957-68.

DNA replication licensing in somatic and germ cells., Eward KL, Obermann EC, Shreeram S, Loddo M, Fanshawe T, Williams C, Jung HI, Prevost AT, Blow JJ, Stoeber K, Williams GH., J Cell Sci. November 15, 2004; 117 (Pt 24): 5875-86.

Intrinsic nuclear import activity of geminin is essential to prevent re-initiation of DNA replication in Xenopus eggs., Yoshida K, Takisawa H, Kubota Y., Genes Cells. January 1, 2005; 10 (1): 63-73.

Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts., Arias EE, Walter JC., Genes Dev. January 1, 2005; 19 (1): 114-26.

Functional domains of the Xenopus replication licensing factor Cdt1., Ferenbach A, Li A, Brito-Martins M, Blow JJ., Nucleic Acids Res. January 12, 2005; 33 (1): 316-24.              

Recombinant Cdt1 induces rereplication of G2 nuclei in Xenopus egg extracts., Maiorano D, Krasinska L, Lutzmann M, Mechali M., Curr Biol. January 26, 2005; 15 (2): 146-53.

Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus., Li A, Blow JJ., EMBO J. January 26, 2005; 24 (2): 395-404.

Licensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extracts., Tsuyama T, Tada S, Watanabe S, Seki M, Enomoto T., Nucleic Acids Res. February 1, 2005; 33 (2): 765-75.            

Caenorhabditis elegans geminin homologue participates in cell cycle regulation and germ line development., Yanagi K, Mizuno T, Tsuyama T, Tada S, Iida Y, Sugimoto A, Eki T, Enomoto T, Hanaoka F., J Biol Chem. May 20, 2005; 280 (20): 19689-94.

Geminin regulates neuronal differentiation by antagonizing Brg1 activity., Seo S, Herr A, Lim JW, Richardson GA, Richardson H, Kroll KL., Genes Dev. July 15, 2005; 19 (14): 1723-34.      

A small gem with great powers: geminin keeps neural progenitors thriving., Aigner S, Gage FH., Dev Cell. August 1, 2005; 9 (2): 171-2.

PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication., Arias EE, Walter JC., Nat Cell Biol. January 1, 2006; 8 (1): 84-90.

Regulation of replication licensing by acetyltransferase Hbo1., Iizuka M, Matsui T, Takisawa H, Smith MM., Mol Cell Biol. February 1, 2006; 26 (3): 1098-108.

Dynamics of DNA binding of replication initiation proteins during de novo formation of pre-replicative complexes in Xenopus egg extracts., Waga S, Zembutsu A., J Biol Chem. April 21, 2006; 281 (16): 10926-34.

Subcellular translocation signals regulate Geminin activity during embryonic development., Boos A, Lee A, Thompson DM, Kroll KL., Biol Cell. June 1, 2006; 98 (6): 363-75.

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1., Jin J, Arias EE, Chen J, Harper JW, Walter JC., Mol Cell. September 1, 2006; 23 (5): 709-21.

One ring to rule them all? Another cellular responsibility for PCNA., Green CM., Trends Mol Med. October 1, 2006; 12 (10): 455-8.

Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision., Davidson IF, Li A, Blow JJ., Mol Cell. November 3, 2006; 24 (3): 433-43.              

A Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus., Lutzmann M, Maiorano D, Méchali M., EMBO J. December 13, 2006; 25 (24): 5764-74.

Cdt1 and geminin: role during cell cycle progression and DNA damage in higher eukaryotes., Tada S., Front Biosci. January 1, 2007; 12 1629-41.

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