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Summary Expression Phenotypes Gene Literature (86) GO Terms (10) Nucleotides (419) Proteins (51) Interactants (322) Wiki
XB-GENEPAGE-1014887

Papers associated with cdt1



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Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus., Li A, Blow JJ., EMBO J. January 26, 2005; 24 (2): 395-404.

Functional domains of the Xenopus replication licensing factor Cdt1., Ferenbach A, Li A, Brito-Martins M, Blow JJ., Nucleic Acids Res. January 12, 2005; 33 (1): 316-24.              

Intrinsic nuclear import activity of geminin is essential to prevent re-initiation of DNA replication in Xenopus eggs., Yoshida K, Takisawa H, Kubota Y., Genes Cells. January 1, 2005; 10 (1): 63-73.

Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts., Arias EE, Walter JC., Genes Dev. January 1, 2005; 19 (1): 114-26.

DNA replication licensing in somatic and germ cells., Eward KL, Obermann EC, Shreeram S, Loddo M, Fanshawe T, Williams C, Jung HI, Prevost AT, Blow JJ, Stoeber K, Williams GH., J Cell Sci. November 15, 2004; 117 (Pt 24): 5875-86.

Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity., Benjamin JM, Torke SJ, Demeler B, McGarry TJ., J Biol Chem. October 29, 2004; 279 (44): 45957-68.

A hypophosphorylated form of RPA34 is a specific component of pre-replication centers., Françon P, Lemaître JM, Dreyer C, Maiorano D, Cuvier O, Méchali M., J Cell Sci. October 1, 2004; 117 (Pt 21): 4909-20.                      

Recruitment of Xenopus Scc2 and cohesin to chromatin requires the pre-replication complex., Takahashi TS, Yiu P, Chou MF, Gygi S, Walter JC., Nat Cell Biol. October 1, 2004; 6 (10): 991-6.

Structural basis for inhibition of the replication licensing factor Cdt1 by geminin., Lee C, Lee C, Hong B, Choi JM, Kim Y, Watanabe S, Ishimi Y, Enomoto T, Tada S, Kim Y, Cho Y., Nature. August 19, 2004; 430 (7002): 913-7.

Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis., Ballabeni A, Melixetian M, Zamponi R, Masiero L, Marinoni F, Helin K., EMBO J. August 4, 2004; 23 (15): 3122-32.

A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition., Saxena S, Yuan P, Dhar SK, Senga T, Takeda D, Robinson H, Kornbluth S, Swaminathan K, Dutta A., Mol Cell. July 23, 2004; 15 (2): 245-58.

A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication., Jares P, Luciani MG, Blow JJ., BMC Mol Biol. June 28, 2004; 5 5.          

The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation., Oehlmann M, Score AJ, Blow JJ., J Cell Biol. April 26, 2004; 165 (2): 181-90.                  

Cell cycle regulation of the licensing activity of Cdt1 in Xenopus laevis., Maiorano D, Rul W, Méchali M., Exp Cell Res. April 15, 2004; 295 (1): 138-49.

Direct interaction of geminin and Six3 in eye development., Del Bene F, Tessmar-Raible K, Wittbrodt J., Nature. February 19, 2004; 427 (6976): 745-9.

The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication., Van Hatten RA, Tutter AV, Holway AH, Khederian AM, Walter JC, Michael WM., J Cell Biol. November 25, 2002; 159 (4): 541-7.          

Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex., Chou DM, Petersen P, Walter JC, Walter G., J Biol Chem. October 25, 2002; 277 (43): 40520-7.

MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts., Edwards MC, Tutter AV, Cvetic C, Gilbert CH, Prokhorova TA, Walter JC., J Biol Chem. September 6, 2002; 277 (36): 33049-57.

Control of DNA replication licensing in a cell cycle., Nishitani H, Lygerou Z., Genes Cells. June 1, 2002; 7 (6): 523-34.        

Identification of Tah11/Sid2 as the ortholog of the replication licensing factor Cdt1 in Saccharomyces cerevisiae., Devault A, Vallen EA, Yuan T, Green S, Bensimon A, Schwob E., Curr Biol. April 16, 2002; 12 (8): 689-94.

Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import., Hodgson B, Li A, Tada S, Blow JJ., Curr Biol. April 16, 2002; 12 (8): 678-83.

Essential role of human CDT1 in DNA replication and chromatin licensing., Rialland M, Sola F, Santocanale C., J Cell Sci. April 1, 2002; 115 (Pt 7): 1435-40.

Oncogenic potential of the DNA replication licensing protein CDT1., Arentson E, Faloon P, Seo J, Moon E, Studts JM, Fremont DH, Choi K., Oncogene. February 14, 2002; 21 (8): 1150-8.

Mammalian nuclei become licensed for DNA replication during late telophase., Dimitrova DS, Prokhorova TA, Blow JJ, Todorov IT, Gilbert DM., J Cell Sci. January 1, 2002; 115 (Pt 1): 51-9.

The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase., Nishitani H, Taraviras S, Lygerou Z, Nishimoto T., J Biol Chem. November 30, 2001; 276 (48): 44905-11.

mei-41 and bub1 block mitosis at two distinct steps in response to incomplete DNA replication in Drosophila embryos., Garner M, van Kreeveld S, Su TT., Curr Biol. October 16, 2001; 11 (20): 1595-9.

The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis., Quinn LM, Herr A, McGarry TJ, Richardson H., Genes Dev. October 15, 2001; 15 (20): 2741-54.    

Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin., Tada S, Li A, Maiorano D, Méchali M, Blow JJ., Nat Cell Biol. February 1, 2001; 3 (2): 107-13.

Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins., Gillespie PJ, Li A, Blow JJ., BMC Biochem. January 1, 2001; 2 15.                

Cell cycle. License withheld--geminin blocks DNA replication., Lygerou Z, Nurse P., Science. December 22, 2000; 290 (5500): 2271-3.

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1., Wohlschlegel JA, Dwyer BT, Dhar SK, Cvetic C, Walter JC, Dutta A., Science. December 22, 2000; 290 (5500): 2309-12.

XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis., Maiorano D, Moreau J, Méchali M., Nature. April 6, 2000; 404 (6778): 622-5.

Characterization of a functional angiotensin II receptor in Xenopus laevis heart., Aiyar N, Baker E, Pullen M, Nuthulaganti P, Bergsma DJ, Kumar C, Nambi P., Pharmacology. April 1, 1994; 48 (4): 242-9.

Molecular cloning, sequencing and functional expression of an amphibian angiotensin II receptor., Ji H, Sandberg K, Zhang Y, Catt KJ., Biochem Biophys Res Commun. July 30, 1993; 194 (2): 756-62.

Amphibian myocardial angiotensin II receptors are distinct from mammalian AT1 and AT2 receptor subtypes., Sandberg K, Ji H, Millan MA, Catt KJ., FEBS Lett. June 24, 1991; 284 (2): 281-4.

Novel angiotensin II antagonists distinguish amphibian from mammalian angiotensin II receptors expressed in Xenopus laevis oocytes., Ji H, Sandberg K, Catt KJ., Mol Pharmacol. February 1, 1991; 39 (2): 120-3.

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