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Summary Expression Phenotypes Gene Literature (58) GO Terms (4) Nucleotides (107) Proteins (67) Interactants (625) Wiki
XB-GENEPAGE-481809

Papers associated with gli2



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Prdm15 acts upstream of Wnt4 signaling in anterior neural development of Xenopus laevis., Saumweber E, Mzoughi S, Khadra A, Werberger A, Schumann S, Guccione E, Schmeisser MJ, Kühl SJ., Front Cell Dev Biol. January 1, 2024; 12 1316048.                            

Cilia-localized GID/CTLH ubiquitin ligase complex regulates protein homeostasis of sonic hedgehog signaling components., Hantel F, Liu H, Fechtner L, Neuhaus H, Ding J, Arlt D, Walentek P, Villavicencio-Lorini P, Gerhardt C, Hollemann T, Pfirrmann T., J Cell Sci. May 1, 2022; 135 (9):                                     

Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development., Sun J, Yoon J, Lee M, Lee HK, Hwang YS, Daar IO., Cell Rep. February 1, 2022; 38 (5): 110312.                                          

Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease., Getwan M, Hoppmann A, Schlosser P, Grand K, Song W, Diehl R, Schroda S, Heeg F, Deutsch K, Hildebrandt F, Lausch E, Köttgen A, Lienkamp SS., Proc Natl Acad Sci U S A. September 28, 2021; 118 (39):                                                   

Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration in Xenopus laevis larvae., Hamilton AM, Balashova OA, Borodinsky LN., Elife. May 6, 2021; 10                               

Modeling endoderm development and disease in Xenopus., Edwards NA, Zorn AM., Curr Top Dev Biol. January 1, 2021; 145 61-90.

The critical role of dysregulated Hh-FOXM1-TPX2 signaling in human hepatocellular carcinoma cell proliferation., Wang Y, Wang H, Yan Z, Li G, Hu G, Zhang H, Huang D, Wang Y, Zhang X, Yan Y, Lu Q, Cheng M, Luo S., Cell Commun Signal. July 28, 2020; 18 (1): 116.              

Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog-Gli Is Required for Tracheoesophageal Separation., Nasr T, Mancini P, Rankin SA, Rankin SA, Edwards NA, Agricola ZN, Kenny AP, Kinney JL, Daniels K, Vardanyan J, Han L, Trisno SL, Cha SW, Wells JM, Kofron MJ, Zorn AM., Dev Cell. December 16, 2019; 51 (6): 665-674.e6.                  

Xenopus slc7a5 is essential for notochord function and eye development., Katada T, Sakurai H., Mech Dev. February 1, 2019; 155 48-59.                

Gli2 is required for the induction and migration of Xenopus laevis neural crest., Cerrizuela S, Vega-López GA, Palacio MB, Tríbulo C, Aybar MJ, Aybar MJ., Mech Dev. December 1, 2018; 154 219-239.                      

Sonic hedgehog antagonists reduce size and alter patterning of the frog inner ear., Zarei S, Zarei K, Fritzsch B, Elliott KL., Dev Neurobiol. December 1, 2017; 77 (12): 1385-1400.                

An analysis of MyoD-dependent transcription using CRISPR/Cas9 gene targeting in Xenopus tropicalis embryos., McQueen C, Pownall ME., Mech Dev. August 1, 2017; 146 1-9.          

High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Michiue T, Yamamoto T, Yasuoka Y, Goto T, Ikeda T, Nagura K, Nakayama T, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 270-290.                  

Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors., Kaminski MM, Tosic J, Kresbach C, Engel H, Klockenbusch J, Müller AL, Pichler R, Grahammer F, Kretz O, Huber TB, Walz G, Arnold SJ, Lienkamp SS., Nat Cell Biol. December 1, 2016; 18 (12): 1269-1280.                  

Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling., Jin Z, Schwend T, Fu J, Bao Z, Liang J, Zhao H, Mei W, Yang J., Development. November 1, 2016; 143 (21): 3944-3955.                        

A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification., Rankin SA, Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM, Shannon JM, Zorn AM., Cell Rep. June 28, 2016; 16 (1): 66-78.                                              

Noggin-Mediated Retinal Induction Reveals a Novel Interplay Between Bone Morphogenetic Protein Inhibition, Transforming Growth Factor β, and Sonic Hedgehog Signaling., Messina A, Lan L, Incitti T, Bozza A, Andreazzoli M, Vignali R, Cremisi F, Bozzi Y, Casarosa S., Stem Cells. August 1, 2015; 33 (8): 2496-508.

Inversion of Sonic hedgehog action on its canonical pathway by electrical activity., Belgacem YH, Borodinsky LN., Proc Natl Acad Sci U S A. March 31, 2015; 112 (13): 4140-5.                              

Prepatterning and patterning of the thalamus along embryonic development of Xenopus laevis., Bandín S, Morona R, González A., Front Neuroanat. February 3, 2015; 9 107.                                                    

Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression., Shi J, Zhao Y, Galati D, Winey M, Klymkowsky MW., Dev Biol. November 15, 2014; 395 (2): 287-98.                    

Gene regulatory networks governing lung specification., Rankin SA, Rankin SA, Zorn AM., J Cell Biochem. August 1, 2014; 115 (8): 1343-50.

Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling., Niewiadomski P, Kong JH, Ahrends R, Ma Y, Humke EW, Khan S, Teruel MN, Novitch BG, Rohatgi R., Cell Rep. January 16, 2014; 6 (1): 168-81.

Stabilization of speckle-type POZ protein (Spop) by Daz interacting protein 1 (Dzip1) is essential for Gli turnover and the proper output of Hedgehog signaling., Schwend T, Jin Z, Jiang K, Mitchell BJ, Jia J, Yang J., J Biol Chem. November 8, 2013; 288 (45): 32809-32820.                

The cytoskeletal protein Zyxin inhibits Shh signaling during the CNS patterning in Xenopus laevis through interaction with the transcription factor Gli1., Martynova NY, Ermolina LV, Ermakova GV, Eroshkin FM, Gyoeva FK, Baturina NS, Zaraisky AG., Dev Biol. August 1, 2013; 380 (1): 37-48.                      

Indian hedgehog signaling is required for proper formation, maintenance and migration of Xenopus neural crest., Agüero TH, Fernández JP, López GA, Tríbulo C, Aybar MJ., Dev Biol. April 15, 2012; 364 (2): 99-113.                    

Thyroid hormone-induced sonic hedgehog signal up-regulates its own pathway in a paracrine manner in the Xenopus laevis intestine during metamorphosis., Hasebe T, Kajita M, Fu L, Shi YB, Ishizuya-Oka A., Dev Dyn. February 1, 2012; 241 (2): 403-14.        

The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1., Jin Z, Mei W, Strack S, Jia J, Yang J., J Biol Chem. October 21, 2011; 286 (42): 36171-9.

Suppressing Wnt signaling by the hedgehog pathway through sFRP-1., He J, Sheng T, Stelter AA, Li C, Zhang X, Sinha M, Luxon BA, Xie J., J Biol Chem. November 24, 2006; 281 (47): 35598-602.

Cooperative requirement of the Gli proteins in neurogenesis., Nguyen V, Chokas AL, Stecca B, Ruiz i Altaba A., Development. July 1, 2005; 132 (14): 3267-79.                      

Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features., Roessler E, Du YZ, Mullor JL, Casas E, Allen WP, Gillessen-Kaesbach G, Roeder ER, Ming JE, Ruiz i Altaba A, Muenke M., Proc Natl Acad Sci U S A. November 11, 2003; 100 (23): 13424-9.          

The amino-terminal region of Gli3 antagonizes the Shh response and acts in dorsoventral fate specification in the developing spinal cord., Meyer NP, Roelink H., Dev Biol. May 15, 2003; 257 (2): 343-55.

A novel function for Hedgehog signalling in retinal pigment epithelium differentiation., Perron M, Boy S, Amato MA, Viczian A, Koebernick K, Pieler T, Harris WA., Development. April 1, 2003; 130 (8): 1565-77.                                  

Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development., Karlstrom RO, Tyurina OV, Kawakami A, Nishioka N, Talbot WS, Sasaki H, Schier AF., Development. April 1, 2003; 130 (8): 1549-64.

Exposure to the herbicide acetochlor alters thyroid hormone-dependent gene expression and metamorphosis in Xenopus Laevis., Crump D, Werry K, Veldhoen N, Van Aggelen G, Helbing CC., Environ Health Perspect. December 1, 2002; 110 (12): 1199-205.

Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity., Persson M, Stamataki D, te Welscher P, Andersson E, Böse J, Rüther U, Ericson J, Briscoe J., Genes Dev. November 15, 2002; 16 (22): 2865-78.

Conserved expression control and shared activity between cognate T-box genes Tbx2 and Tbx3 in connection with Sonic hedgehog signaling during Xenopus eye development., Takabatake Y, Takabatake T, Sasagawa S, Takeshima K., Dev Growth Differ. August 1, 2002; 44 (4): 257-71.              

Gli1 can rescue the in vivo function of Gli2., Bai CB, Joyner AL., Development. December 1, 2001; 128 (24): 5161-72.

Anorectal malformations caused by defects in sonic hedgehog signaling., Mo R, Kim JH, Zhang J, Chiang C, Hui CC, Kim PC., Am J Pathol. August 1, 2001; 159 (2): 765-74.

Expression pattern of Irx1 and Irx2 during mouse digit development., Zülch A, Becker MB, Gruss P., Mech Dev. August 1, 2001; 106 (1-2): 159-62.

Hexokinase I is a Gli2-responsive gene expressed in the embryonic CNS., Brewster R, Ruiz i Altaba A., Mech Dev. December 1, 2000; 99 (1-2): 159-62.  

Similar expression and regulation of Gli2 and Gli3 in the chick limb bud., Schweitzer R, Vogan KJ, Tabin CJ., Mech Dev. November 1, 2000; 98 (1-2): 171-4.

Distinct expression of two types of Xenopus Patched genes during early embryogenesis and hindlimb development., Takabatake T, Takahashi TC, Takabatake Y, Yamada K, Ogawa M, Takeshima K., Mech Dev. November 1, 2000; 98 (1-2): 99-104.            

Gli2 functions in FGF signaling during antero-posterior patterning., Brewster R, Mullor JL, Ruiz i Altaba A., Development. October 1, 2000; 127 (20): 4395-405.            

Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites., Borycki A, Brown AM, Emerson CP., Development. May 1, 2000; 127 (10): 2075-87.

Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation., Park HL, Bai C, Platt KA, Matise MP, Beeghly A, Hui CC, Nakashima M, Joyner AL., Development. April 1, 2000; 127 (8): 1593-605.

Distinct and regulated activities of human Gli proteins in Drosophila., von Mering C, Basler K., Curr Biol. November 18, 1999; 9 (22): 1319-22.

Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling., Sasaki H, Nishizaki Y, Hui C, Nakafuku M, Kondoh H., Development. September 1, 1999; 126 (17): 3915-24.

Gli proteins encode context-dependent positive and negative functions: implications for development and disease., Ruiz i Altaba A., Development. June 1, 1999; 126 (14): 3205-16.                

Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus., Motoyama J, Liu J, Mo R, Ding Q, Post M, Hui CC., Nat Genet. September 1, 1998; 20 (1): 54-7.

The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants., Hardcastle Z, Mo R, Hui CC, Sharpe PT., Development. August 1, 1998; 125 (15): 2803-11.

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