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Summary Expression Phenotypes Gene Literature (84) GO Terms (6) Nucleotides (95) Proteins (54) Interactants (861) Wiki
XB-GENEPAGE-485516

Papers associated with lef1



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Competence for neural crest induction is controlled by hydrostatic pressure through Yap., Alasaadi DN, Alvizi L, Hartmann J, Stillman N, Moghe P, Hiiragi T, Mayor R., Nat Cell Biol. March 18, 2024;                                     


Mechanical Tensions Regulate Gene Expression in the Xenopus laevis Axial Tissues., Eroshkin FM, Fefelova EA, Bredov DV, Orlov EE, Kolyupanova NM, Mazur AM, Sokolov AS, Zhigalova NA, Prokhortchouk EB, Nesterenko AM, Zaraisky AG., Int J Mol Sci. January 10, 2024; 25 (2):         


RNF2 regulates Wnt/ß-catenin signaling via TCF7L1 destabilization., Koo Y, Han W, Keum BR, Lutz L, Yun SH, Kim GH, Han JK., Sci Rep. November 13, 2023; 13 (1): 19750.            


The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E., Nat Commun. October 5, 2023; 14 (1): 6173.                                


Unravelling the limb regeneration mechanisms of Polypedates maculatus, a sub-tropical frog, by transcriptomics., Mahapatra C, Naik P, Swain SK, Mohapatra PP., BMC Genomics. March 16, 2023; 24 (1): 122.                                                


HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs., Liang T, Bai J, Zhou W, Lin H, Ma S, Zhu X, Tao Q, Xi Q., Cell Rep. July 12, 2022; 40 (2): 111038.                              


The role of Xenopus developmental biology in unraveling Wnt signalling and antero-posterior axis formation., Niehrs C., Dev Biol. February 1, 2022; 482 1-6.


Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension., Mok GF, Folkes L, Weldon SA, Maniou E, Martinez-Heredia V, Godden AM, Williams RM, Sauka-Spengler T, Wheeler GN, Moxon S, Münsterberg AE., Nat Commun. February 19, 2021; 12 (1): 1157.              


Model systems for regeneration: Xenopus., Phipps LS, Marshall L, Dorey K, Amaya E., Development. March 19, 2020; 147 (6):           


The myeloid lineage is required for the emergence of a regeneration-permissive environment following Xenopus tail amputation., Aztekin C, Hiscock TW, Butler R, De Jesús Andino F, Robert J, Gurdon JB, Jullien J., Development. February 5, 2020; 147 (3):                                     


Lef1 regulates caveolin expression and caveolin dependent endocytosis, a process necessary for Wnt5a/Ror2 signaling during Xenopus gastrulation., Puzik K, Tonnier V, Opper I, Eckert A, Zhou L, Kratzer MC, Noble FL, Nienhaus GU, Gradl D., Sci Rep. October 30, 2019; 9 (1): 15645.                          


Using Zebrafish to Study Collective Cell Migration in Development and Disease., Olson HM, Nechiporuk AV., Front Cell Dev Biol. January 1, 2018; 6 83.            


A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL, Medina-Ruiz S, Borday C, Bernard E, Vert JP, Eisen MB, Harland RM, Monsoro-Burq AH., PLoS Biol. October 19, 2017; 15 (10): e2004045.                                              


SHH signaling directed by two oral epithelium-specific enhancers controls tooth and oral development., Sagai T, Amano T, Maeno A, Kiyonari H, Seo H, Cho SW, Shiroishi T., Sci Rep. October 11, 2017; 7 (1): 13004.          


High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Michiue T, Yamamoto T, Yasuoka Y, Goto T, Ikeda T, Nagura K, Nakayama T, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 270-290.                  


Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis., Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MD, Zhang K, Merkurjev D, De Robertis EM., Proc Natl Acad Sci U S A. April 11, 2017; 114 (15): E3081-E3090.                        


Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling., Han W, Lee H, Lee H, Han JK., Sci Rep. February 15, 2017; 7 42590.                        


Functional differences between Tcf1 isoforms in early Xenopus development., Roël G, Van Den Broek O, Destrée O., Int J Dev Biol. January 1, 2017; 61 (1-2): 29-34.          


Controlled levels of canonical Wnt signaling are required for neural crest migration., Maj E, Künneke L, Loresch E, Grund A, Melchert J, Pieler T, Aspelmeier T, Borchers A., Dev Biol. September 1, 2016; 417 (1): 77-90.                          


A Molecular atlas of Xenopus respiratory system development., Rankin SA, Rankin SA, Thi Tran H, Wlizla M, Mancini P, Shifley ET, Bloor SD, Han L, Vleminckx K, Vleminckx K, Wert SE, Zorn AM., Dev Dyn. January 1, 2015; 244 (1): 69-85.                    


Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway., Amado NG, Predes D, Fonseca BF, Cerqueira DM, Reis AH, Dudenhoeffer AC, Borges HL, Mendes FA, Abreu JG., J Biol Chem. December 19, 2014; 289 (51): 35456-67.                  


In vivo analysis of formation and endocytosis of the Wnt/β-catenin signaling complex in zebrafish embryos., Hagemann AI, Kurz J, Kauffeld S, Chen Q, Reeves PM, Weber S, Schindler S, Davidson G, Kirchhausen T, Scholpp S., J Cell Sci. September 15, 2014; 127 (Pt 18): 3970-82.                  


Design and use of transgenic reporter strains for detecting activity of signaling pathways in Xenopus., Tran HT, Vleminckx K, Vleminckx K., Methods. April 1, 2014; 66 (3): 422-32.


A genome-wide survey of maternal and embryonic transcripts during Xenopus tropicalis development., Paranjpe SS, Jacobi UG, van Heeringen SJ, Veenstra GJ., BMC Genomics. November 6, 2013; 14 762.              


The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling., Wang F, Hu W, Xian J, Ohnuma S, Brenton JD., Dev Biol. July 1, 2013; 379 (1): 16-27.                            


Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling., Huang X, McGann JC, Liu BY, Hannoush RN, Lill JR, Pham V, Newton K, Kakunda M, Liu J, Yu C, Hymowitz SG, Hongo JA, Wynshaw-Boris A, Polakis P, Harland RM, Dixit VM., Science. March 22, 2013; 339 (6126): 1441-5.


The Wnt signaling mediator tcf1 is required for expression of foxd3 during Xenopus gastrulation., Janssens S, Van Den Broek O, Davenport IR, Akkers RC, Liu F, Veenstra GJ, Hoppler S, Vleminckx K, Vleminckx K, Destrée O., Int J Dev Biol. January 1, 2013; 57 (1): 49-54.    


β-Catenin-independent activation of TCF1/LEF1 in human hematopoietic tumor cells through interaction with ATF2 transcription factors., Grumolato L, Liu G, Haremaki T, Mungamuri SK, Mong P, Akiri G, Lopez-Bergami P, Arita A, Anouar Y, Mlodzik M, Ronai ZA, Brody J, Weinstein DC, Aaronson SA., PLoS Genet. January 1, 2013; 9 (8): e1003603.            


SUMOylated SoxE factors recruit Grg4 and function as transcriptional repressors in the neural crest., Lee PC, Taylor-Jaffe KM, Nordin KM, Prasad MS, Lander RM, LaBonne C., J Cell Biol. September 3, 2012; 198 (5): 799-813.              


Amer2 protein is a novel negative regulator of Wnt/β-catenin signaling involved in neuroectodermal patterning., Pfister AS, Tanneberger K, Schambony A, Behrens J., J Biol Chem. January 13, 2012; 287 (3): 1734-41.      


Functional analyses of vertebrate TCF proteins in C. elegans embryos., Robertson SM, Lo MC, Odom R, Yang XD, Medina J, Huang S, Lin R., Dev Biol. July 1, 2011; 355 (1): 115-23.


Non-canonical wnt signals antagonize and canonical wnt signals promote cell proliferation in early kidney development., McCoy KE, Zhou X, Vize PD., Dev Dyn. June 1, 2011; 240 (6): 1558-66.          


Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2., Hikasa H, Sokol SY., J Biol Chem. April 8, 2011; 286 (14): 12093-100.


Microarray identification of novel downstream targets of FoxD4L1/D5, a critical component of the neural ectodermal transcriptional network., Yan B, Neilson KM, Moody SA., Dev Dyn. December 1, 2010; 239 (12): 3467-80.                  


Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria., Hernandez L, Roux KJ, Wong ES, Mounkes LC, Mutalif R, Navasankari R, Rai B, Cool S, Jeong JW, Wang H, Lee HS, Kozlov S, Grunert M, Keeble T, Jones CM, Meta MD, Young SG, Daar IO, Burke B, Perantoni AO, Stewart CL., Dev Cell. September 14, 2010; 19 (3): 413-25.  


beta-Catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2., Blythe SA, Cha SW, Tadjuidje E, Heasman J, Klein PS., Dev Cell. August 17, 2010; 19 (2): 220-31.      


Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction., Wang Y, Fu Y, Gao L, Zhu G, Liang J, Gao C, Huang B, Fenger U, Niehrs C, Chen YG, Chen YG, Wu W., J Biol Chem. April 2, 2010; 285 (14): 10890-901.                            


A directional Wnt/beta-catenin-Sox2-proneural pathway regulates the transition from proliferation to differentiation in the Xenopus retina., Agathocleous M, Iordanova I, Willardsen MI, Xue XY, Vetter ML, Harris WA, Moore KB., Development. October 1, 2009; 136 (19): 3289-99.                          


Integration of telencephalic Wnt and hedgehog signaling center activities by Foxg1., Danesin C, Peres JN, Johansson M, Snowden V, Cording A, Papalopulu N, Houart C., Dev Cell. April 1, 2009; 16 (4): 576-87.              


Requirement of Wnt/beta-catenin signaling in pronephric kidney development., Lyons JP, Miller RK, Zhou X, Weidinger G, Deroo T, Denayer T, Park JI, Ji H, Hong JY, Li A, Moon RT, Jones EA, Vleminckx K, Vleminckx K, Vize PD, McCrea PD., Mech Dev. January 1, 2009; 126 (3-4): 142-59.        


Lef1 plays a role in patterning the mesoderm and ectoderm in Xenopus tropicalis., Roel G, Gent YY, Peterson-Maduro J, Verbeek FJ, Destree O., Int J Dev Biol. January 1, 2009; 53 (1): 81-9.          


Evolution of non-coding regulatory sequences involved in the developmental process: reflection of differential employment of paralogous genes as highlighted by Sox2 and group B1 Sox genes., Kamachi Y, Iwafuchi M, Okuda Y, Takemoto T, Uchikawa M, Kondoh H., Proc Jpn Acad Ser B Phys Biol Sci. January 1, 2009; 85 (2): 55-68.                  


Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL., Chitalia VC, Foy RL, Bachschmid MM, Zeng L, Panchenko MV, Zhou MI, Bharti A, Seldin DC, Lecker SH, Dominguez I, Cohen HT., Nat Cell Biol. October 1, 2008; 10 (10): 1208-16.        


Cold-inducible RNA binding protein (CIRP), a novel XTcf-3 specific target gene regulates neural development in Xenopus., van Venrooy S, Fichtner D, Kunz M, Wedlich D, Gradl D., BMC Dev Biol. August 7, 2008; 8 77.                                


Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia., Bergmann C, Fliegauf M, Brüchle NO, Frank V, Olbrich H, Kirschner J, Schermer B, Schmedding I, Kispert A, Kränzlin B, Nürnberg G, Becker C, Grimm T, Girschick G, Lynch SA, Kelehan P, Senderek J, Neuhaus TJ, Stallmach T, Zentgraf H, Nürnberg P, Gretz N, Lo C, Lienkamp S, Schäfer T, Walz G, Benzing T, Zerres K, Omran H., Am J Hum Genet. April 1, 2008; 82 (4): 959-70.


Myeloid translocation gene family members associate with T-cell factors (TCFs) and influence TCF-dependent transcription., Moore AC, Amann JM, Williams CS, Tahinci E, Farmer TE, Martinez JA, Yang G, Luce KS, Lee E, Hiebert SW., Mol Cell Biol. February 1, 2008; 28 (3): 977-87.


Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells., Sinner D, Kordich JJ, Spence JR, Opoka R, Rankin S, Rankin S, Lin SC, Jonatan D, Zorn AM, Wells JM., Mol Cell Biol. November 1, 2007; 27 (22): 7802-15.                


Wnt/beta-catenin signaling controls Mespo expression to regulate segmentation during Xenopus somitogenesis., Wang J, Li S, Chen Y, Chen Y, Ding X., Dev Biol. April 15, 2007; 304 (2): 836-47.                    


Xom interacts with and stimulates transcriptional activity of LEF1/TCFs: implications for ventral cell fate determination during vertebrate embryogenesis., Gao H, Wu B, Giese R, Zhu Z., Cell Res. April 1, 2007; 17 (4): 345-56.


Neural induction in Xenopus requires inhibition of Wnt-beta-catenin signaling., Heeg-Truesdell E, LaBonne C., Dev Biol. October 1, 2006; 298 (1): 71-86.                    

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