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XB-GENEPAGE-6043717
Papers associated with p2rx2
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A histidine scan to probe the flexibility of the rat P2X2 receptor zinc-binding site., Tittle RK, Power JM, Hume RI., J Biol Chem. July 6, 2007; 282 (27): 19526-33. |
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Regulation of the desensitization and ion selectivity of ATP-gated P2X2 channels by phosphoinositides., Fujiwara Y, Kubo Y., J Physiol. October 1, 2006; 576 (Pt 1): 135-49. |
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Extracellular histidine residues identify common structural determinants in the copper/zinc P2X2 receptor modulation., Lorca RA, Coddou C, Gazitúa MC, Bull P, Arredondo C, Huidobro-Toro JP., J Neurochem. October 1, 2005; 95 (2): 499-512. |
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Regulatory interdependence of cloned epithelial Na+ channels and P2X receptors., Wildman SS, Marks J, Churchill LJ, Peppiatt CM, Chraibi A, Shirley DG, Horisberger JD, King BF, Unwin RJ., J Am Soc Nephrol. September 1, 2005; 16 (9): 2586-97. |
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An intersubunit zinc binding site in rat P2X2 receptors., Nagaya N, Tittle RK, Saar N, Dellal SS, Hume RI., J Biol Chem. July 15, 2005; 280 (28): 25982-93. |
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Characterization of voltage-dependent gating of P2X2 receptor/channel., Nakazawa K, Ohno Y., Eur J Pharmacol. January 31, 2005; 508 (1-3): 23-30. |
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Subunit-specific coupling between gamma-aminobutyric acid type A and P2X2 receptor channels., Boué-Grabot E, Toulmé E, Emerit MB, Garret M., J Biol Chem. December 10, 2004; 279 (50): 52517-25. |
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Trimeric architecture of homomeric P2X2 and heteromeric P2X1+2 receptor subtypes., Aschrafi A, Sadtler S, Niculescu C, Rettinger J, Schmalzing G., J Mol Biol. September 3, 2004; 342 (1): 333-43. |
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Desensitization of P2X2 receptor/channel pore mutants., Nakazawa K, Ohno Y., Eur J Pharmacol. July 8, 2004; 495 (1): 27-33. |
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Density-dependent changes of the pore properties of the P2X2 receptor channel., Fujiwara Y, Kubo Y., J Physiol. July 1, 2004; 558 (Pt 1): 31-43. |
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Cross-talk and co-trafficking between rho1/GABA receptors and ATP-gated channels., Boué-Grabot E, Emerit MB, Toulmé E, Séguéla P, Garret M., J Biol Chem. February 20, 2004; 279 (8): 6967-75. |
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Amino acid substitutions from an indispensable disulfide bond affect P2X2 receptor activation., Nakazawa K, Ojima H, Ishii-Nozawa R, Takeuchi K, Ohno Y., Eur J Pharmacol. January 1, 2004; 483 (1): 29-35. |
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Intracellular disulfide bond that affects ATP responsiveness of P2X2 receptor/channel., Nakazawa K, Ojima H, Ishii-Nozawa R, Takeuchi K, Ohno Y., Eur J Pharmacol. August 8, 2003; 474 (2-3): 205-8. |
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Expression level dependent changes in the properties of P2X2 receptors., Clyne JD, Brown TC, Hume RI., Neuropharmacology. March 1, 2003; 44 (3): 403-12. |
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Intracellular cross talk and physical interaction between two classes of neurotransmitter-gated channels., Boué-Grabot E, Barajas-López C, Chakfe Y, Blais D, Bélanger D, Emerit MB, Séguéla P., J Neurosci. February 15, 2003; 23 (4): 1246-53. |
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Allosteric modulation of native cochlear P2X receptors: insights from comparison with recombinant P2X2 receptors., Kanjhan R, Raybould NP, Jagger DJ, Greenwood D, Housley GD., Audiol Neurootol. January 1, 2003; 8 (3): 115-28. |
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Heteromultimerization modulates P2X receptor functions through participating extracellular and C-terminal subdomains., Koshimizu TA, Ueno S, Tanoue A, Yanagihara N, Stojilkovic SS, Tsujimoto G., J Biol Chem. December 6, 2002; 277 (49): 46891-9. |
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Evidence for non-independent gating of P2X2 receptors expressed in Xenopus oocytes., Ding S, Sachs F., BMC Neurosci. November 6, 2002; 3 17. ![]() |
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Size of side-chain at channel pore mouth affects Ca(2+) block of P2X(2) receptor., Nakazawa K, Sawa H, Ojima H, Ishii-Nozawa R, Takeuchi K, Ohno Y., Eur J Pharmacol. August 9, 2002; 449 (3): 207-11. |
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Control of P2X(2) channel permeability by the cytosolic domain., Eickhorst AN, Berson A, Cockayne D, Lester HA, Khakh BS., J Gen Physiol. August 1, 2002; 120 (2): 119-31. ![]() |
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Ethanol sensitivity in ATP-gated P2X receptors is subunit dependent., Davies DL, Machu TK, Guo Y, Alkana RL., Alcohol Clin Exp Res. June 1, 2002; 26 (6): 773-8. |
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A highly conserved tryptophane residue indispensable for cloned rat neuronal P2X receptor activation., Nakazawa K, Ojima H, Ohno Y., Neurosci Lett. May 17, 2002; 324 (2): 141-4. |
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Mutational analysis of the conserved cysteines of the rat P2X2 purinoceptor., Clyne JD, Wang LF, Hume RI., J Neurosci. May 15, 2002; 22 (10): 3873-80. |
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The role of histidine residues in modulation of the rat P2X(2) purinoceptor by zinc and pH., Clyne JD, LaPointe LD, Hume RI., J Physiol. March 1, 2002; 539 (Pt 2): 347-59. |
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Single amino acid residue influences the distribution pattern of an inwardly rectifying potassium channel in polarized cells., Wild K, Paysan J., Cell Tissue Res. January 1, 2002; 307 (1): 47-55. |
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Inflammatory mediators potentiate ATP-gated channels through the P2X(3) subunit., Paukert M, Osteroth R, Geisler HS, Brandle U, Glowatzki E, Ruppersberg JP, Gründer S., J Biol Chem. June 15, 2001; 276 (24): 21077-82. |
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Activation-dependent changes in receptor distribution and dendritic morphology in hippocampal neurons expressing P2X2-green fluorescent protein receptors., Khakh BS, Smith WB, Chiu CS, Ju D, Davidson N, Lester HA., Proc Natl Acad Sci U S A. April 24, 2001; 98 (9): 5288-93. |
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Coexpression of P2X(3) and P2X(2) receptor subunits in varying amounts generates heterogeneous populations of P2X receptors that evoke a spectrum of agonist responses comparable to that seen in sensory neurons., Liu M, King BF, Dunn PM, Rong W, Townsend-Nicholson A, Burnstock G., J Pharmacol Exp Ther. March 1, 2001; 296 (3): 1043-50. |
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Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors., Kim YC, Brown SG, Harden TK, Boyer JL, Dubyak G, King BF, Burnstock G, Jacobson KA., J Med Chem. February 1, 2001; 44 (3): 340-9. |
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State-dependent cross-inhibition between transmitter-gated cation channels., Khakh BS, Zhou X, Sydes J, Galligan JJ, Lester HA., Nature. July 27, 2000; 406 (6794): 405-10. |
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In search of selective P2 receptor ligands: interaction of dihydropyridine derivatives at recombinant rat P2X(2) receptors., Jacobson KA, Kim YC, King BF., J Auton Nerv Syst. July 3, 2000; 81 (1-3): 152-7. |
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Coexpression of rat P2X2 and P2X6 subunits in Xenopus oocytes., King BF, Townsend-Nicholson A, Wildman SS, Thomas T, Spyer KM, Burnstock G., J Neurosci. July 1, 2000; 20 (13): 4871-7. |
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A protein kinase C site highly conserved in P2X subunits controls the desensitization kinetics of P2X(2) ATP-gated channels., Boué-Grabot E, Archambault V, Séguéla P., J Biol Chem. April 7, 2000; 275 (14): 10190-5. |
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Molecular and functional characterization of human P2X(2) receptors., Lynch KJ, Touma E, Niforatos W, Kage KL, Burgard EC, van Biesen T, Kowaluk EA, Jarvis MF., Mol Pharmacol. December 1, 1999; 56 (6): 1171-81. |
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Contribution of individual subunits to the multimeric P2X(2) receptor: estimates based on methanethiosulfonate block at T336C., Stoop R, Thomas S, Rassendren F, Kawashima E, Buell G, Surprenant A, North RA., Mol Pharmacol. November 1, 1999; 56 (5): 973-81. |
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Identification of amino acids within the P2X2 receptor C-terminus that regulate desensitization., Smith FM, Humphrey PP, Murrell-Lagnado RD., J Physiol. October 1, 1999; 520 Pt 1 91-9. |
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5-Hydroxytryptamine inhibits P2X2 receptor channel pore mutants., Nakazawa K, Ohno Y., Cell Mol Neurobiol. October 1, 1999; 19 (5): 665-9. |
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Differential modulation by copper and zinc of P2X2 and P2X4 receptor function., Xiong K, Peoples RW, Montgomery JP, Chiang Y, Stewart RR, Weight FF, Li C., J Neurophysiol. May 1, 1999; 81 (5): 2088-94. |
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Single channel properties of P2X2 purinoceptors., Ding S, Sachs F., J Gen Physiol. May 1, 1999; 113 (5): 695-720. ![]() |
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Neighboring glycine residues are essential for P2X2 receptor/channel function., Nakazawa K, Ohno Y., Eur J Pharmacol. April 16, 1999; 370 (3): R5-6. |
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Block and unblock by imipramine of cloned and mutated P2X2 receptor/channel expressed in Xenopus oocytes., Nakazawa K, Inoue K, Ohno Y., Neurosci Lett. April 2, 1999; 264 (1-3): 93-6. |
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Selectivity of diadenosine polyphosphates for rat P2X receptor subunits., Wildman SS, Brown SG, King BF, Burnstock G., Eur J Pharmacol. February 12, 1999; 367 (1): 119-23. |
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Antagonistic properties of the suramin analogue NF023 at heterologously expressed P2X receptors., Soto F, Lambrecht G, Nickel P, Stühmer W, Busch AE., Neuropharmacology. January 1, 1999; 38 (1): 141-9. |
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Identification of a site that modifies desensitization of P2X2 receptors., Zhou Z, Monsma LR, Hume RI., Biochem Biophys Res Commun. November 27, 1998; 252 (3): 541-5. |
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A pyridoxine cyclic phosphate and its 6-azoaryl derivative selectively potentiate and antagonize activation of P2X1 receptors., Jacobson KA, Kim YC, Wildman SS, Mohanram A, Harden TK, Boyer JL, King BF, Burnstock G., J Med Chem. June 18, 1998; 41 (13): 2201-6. |
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Membrane topology of an ATP-gated ion channel (P2X receptor)., Newbolt A, Stoop R, Virginio C, Surprenant A, North RA, Buell G, Rassendren F., J Biol Chem. June 12, 1998; 273 (24): 15177-82. |
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An asparagine residue regulating conductance through P2X2 receptor/channels., Nakazawa K, Inoue K, Ohno Y., Eur J Pharmacol. April 17, 1998; 347 (1): 141-4. |
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An aspartic acid residue near the second transmembrane segment of ATP receptor/channel regulates agonist sensitivity., Nakazawa K, Ohno Y, Inoue K., Biochem Biophys Res Commun. March 17, 1998; 244 (2): 599-603. |
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Zn2+ modulation of ATP-responses at recombinant P2X2 receptors and its dependence on extracellular pH., Wildman SS, King BF, Burnstock G., Br J Pharmacol. March 1, 1998; 123 (6): 1214-20. |
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Two mechanisms for inward rectification of current flow through the purinoceptor P2X2 class of ATP-gated channels., Zhou Z, Hume RI., J Physiol. March 1, 1998; 507 ( Pt 2) 353-64. |
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