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Summary Expression Phenotypes Gene Literature (72) GO Terms (5) Nucleotides (86) Proteins (38) Interactants (137) Wiki
XB-GENEPAGE-5896430

Papers associated with pycard



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referenced by:


Characterization of neutral and cationic amino acid transport in Xenopus oocytes., Campa MJ, Kilberg MS., J Cell Physiol. December 1, 1989; 141 (3): 645-52.


Mechanism of polyamine spermidine uptake by Xenopus laevis oocytes., Khan NA, Quemener V, Havouis R, Moulinoux JP., Biochem Int. January 1, 1990; 21 (4): 607-13.


Expression of rat liver Na+/L-alanine co-transport in Xenopus laevis oocytes. Effect of glucagon in vivo., Palacin M, Werner A, Dittmer J, Murer H, Biber J., Biochem J. August 15, 1990; 270 (1): 189-95.


Expression of rat liver glutamine transporters in Xenopus laevis oocytes., Taylor PM, Mackenzie B, Low SY, Rennie MJ., J Biol Chem. February 25, 1992; 267 (6): 3873-7.


Genetic transfer of a nonpeptide antagonist binding site to a previously unresponsive angiotensin receptor., Ji H, Zheng W, Zhang Y, Catt KJ, Sandberg K., Proc Natl Acad Sci U S A. September 26, 1995; 92 (20): 9240-4.


Cloning and functional characterization of a system ASC-like Na+-dependent neutral amino acid transporter., Utsunomiya-Tate N, Endou H, Kanai Y., J Biol Chem. June 21, 1996; 271 (25): 14883-90.


ASCT-1 is a neutral amino acid exchanger with chloride channel activity., Zerangue N, Kavanaugh MP., J Biol Chem. November 8, 1996; 271 (45): 27991-4.


Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel., Fink M, Duprat F, Lesage F, Reyes R, Romey G, Heurteaux C, Lazdunski M., EMBO J. December 16, 1996; 15 (24): 6854-62.


Mechanism of enhancement of slow delayed rectifier current by extracellular sulfhydryl modification., Yao JA, Jiang M, Tseng GN., Am J Physiol. July 1, 1997; 273 (1 Pt 2): H208-19.


Cystic fibrosis transmembrane conductance regulator (CFTR) anion binding as a probe of the pore., Mansoura MK, Smith SS, Choi AD, Richards NW, Strong TV, Drumm ML, Collins FS, Dawson DC., Biophys J. March 1, 1998; 74 (3): 1320-32.


Cysteine-scanning mutagenesis of flanking regions at the boundary between external loop I or IV and transmembrane segment II or VII in the GLUT1 glucose transporter., Olsowski A, Monden I, Keller K., Biochemistry. July 28, 1998; 37 (30): 10738-45.


Chimeric constructs between human and rat equilibrative nucleoside transporters (hENT1 and rENT1) reveal hENT1 structural domains interacting with coronary vasoactive drugs., Sundaram M, Yao SY, Ng AM, Griffiths M, Cass CE, Baldwin SA, Young JD., J Biol Chem. August 21, 1998; 273 (34): 21519-25.


Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel., Ashfield R, Gribble FM, Ashcroft SJ, Ashcroft FM., Diabetes. June 1, 1999; 48 (6): 1341-7.


Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2., Loewen SK, Ng AM, Yao SY, Cass CE, Baldwin SA, Young JD., J Biol Chem. August 27, 1999; 274 (35): 24475-84.


The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux., Bröer A, Brookes N, Ganapathy V, Dimmer KS, Wagner CA, Lang F, Bröer S., J Neurochem. November 1, 1999; 73 (5): 2184-94.


A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo., Lee SK, Anzick SL, Choi JE, Bubendorf L, Guan XY, Jung YK, Kallioniemi OP, Kononen J, Trent JM, Azorsa D, Jhun BH, Cheong JH, Lee YC, Meltzer PS, Lee JW, Lee JW., J Biol Chem. November 26, 1999; 274 (48): 34283-93.


Identification and characterization of a Na(+)-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L-amino acids., Fukasawa Y, Segawa H, Kim JY, Chairoungdua A, Kim DK, Matsuo H, Cha SH, Endou H, Kanai Y., J Biol Chem. March 31, 2000; 275 (13): 9690-8.


Reorientation of aquaporin-1 topology during maturation in the endoplasmic reticulum., Lu Y, Turnbull IR, Bragin A, Carveth K, Verkman AS, Skach WR., Mol Biol Cell. September 1, 2000; 11 (9): 2973-85.


Helix packing of functionally important regions of the cardiac Na(+)-Ca(2+) exchanger., Qiu Z, Nicoll DA, Philipson KD., J Biol Chem. January 5, 2001; 276 (1): 194-9.


Equilibrative nucleoside transporters: mapping regions of interaction for the substrate analogue nitrobenzylthioinosine (NBMPR) using rat chimeric proteins., Sundaram M, Yao SY, Ng AM, Cass CE, Baldwin SA, Young JD., Biochemistry. July 10, 2001; 40 (27): 8146-51.


Structural basis for the interference between nicorandil and sulfonylurea action., Reimann F, Ashcroft FM, Gribble FM., Diabetes. October 1, 2001; 50 (10): 2253-9.


A disulfide bond is required for functional assembly of NCX1 from complementary fragments., Qiu Z, Chen J, Nicoll DA, Philipson KD., Biochem Biophys Res Commun. October 5, 2001; 287 (4): 825-8.


Identification and characterization of a novel member of the heterodimeric amino acid transporter family presumed to be associated with an unknown heavy chain., Chairoungdua A, Kanai Y, Matsuo H, Inatomi J, Kim DK, Endou H., J Biol Chem. December 28, 2001; 276 (52): 49390-9.


The oxidant thimerosal modulates gating behavior of KCNQ1 by interaction with the channel outer shell., Kerst G, Brousos H, Schreiber R, Nitschke R, Hug MJ, Greger R, Bleich M., J Membr Biol. March 15, 2002; 186 (2): 89-100.


Characterisation and cloning of a Na(+)-dependent broad-specificity neutral amino acid transporter from NBL-1 cells: a novel member of the ASC/B(0) transporter family., Pollard M, Meredith D, McGivan JD., Biochim Biophys Acta. April 12, 2002; 1561 (2): 202-8.


Identification of a novel Na+-independent acidic amino acid transporter with structural similarity to the member of a heterodimeric amino acid transporter family associated with unknown heavy chains., Matsuo H, Kanai Y, Kim JY, Chairoungdua A, Kim DK, Inatomi J, Shigeta Y, Ishimine H, Chaekuntode S, Tachampa K, Choi HW, Babu E, Fukuda J, Endou H., J Biol Chem. June 7, 2002; 277 (23): 21017-26.


Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocation., Yao SY, Ng AM, Vickers MF, Sundaram M, Cass CE, Baldwin SA, Young JD., J Biol Chem. July 12, 2002; 277 (28): 24938-48.


Cooperativity and flexibility of cystic fibrosis transmembrane conductance regulator transmembrane segments participate in membrane localization of a charged residue., Carveth K, Buck T, Anthony V, Skach WR., J Biol Chem. October 18, 2002; 277 (42): 39507-14.


Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides., Reimann F, Dabrowski M, Jones P, Gribble FM, Ashcroft FM., J Physiol. February 15, 2003; 547 (Pt 1): 159-68.


Cation stoichiometry and cation pathway in the Na,K-ATPase and nongastric H,K-ATPase., Horisberger JD, Guennoun S, Burnay M, Geering K., Ann N Y Acad Sci. April 1, 2003; 986 127-32.


Cross-linking of glycine receptor transmembrane segments two and three alters coupling of ligand binding with channel opening., Lobo IA, Trudell JR, Harris RA., J Neurochem. August 1, 2004; 90 (4): 962-9.


The amino acid transporter asc-1 is not involved in cystinuria., Pineda M, Font M, Bassi MT, Manzoni M, Borsani G, Marigo V, Fernández E, Río RM, Purroy J, Zorzano A, Nunes V, Palacín M., Kidney Int. October 1, 2004; 66 (4): 1453-64.


Mutational analysis of the alpha-1 repeat of the cardiac Na(+)-Ca2+ exchanger., Ottolia M, Nicoll DA, Philipson KD., J Biol Chem. January 14, 2005; 280 (2): 1061-9.


Secondary structure and gating rearrangements of transmembrane segments in rat P2X4 receptor channels., Silberberg SD, Chang TH, Swartz KJ., J Gen Physiol. April 1, 2005; 125 (4): 347-59.                


Recent progress in structure-function analyses of Nramp proton-dependent metal-ion transporters., Courville P, Chaloupka R, Cellier MF., Biochem Cell Biol. December 1, 2006; 84 (6): 960-78.


Specific mutations in transmembrane helix 8 of human concentrative Na+/nucleoside cotransporter hCNT1 affect permeant selectivity and cation coupling., Slugoski MD, Loewen SK, Ng AM, Smith KM, Yao SY, Karpinski E, Cass CE, Baldwin SA, Young JD., Biochemistry. February 13, 2007; 46 (6): 1684-93.


Ivermectin Interaction with transmembrane helices reveals widespread rearrangements during opening of P2X receptor channels., Silberberg SD, Li M, Swartz KJ., Neuron. April 19, 2007; 54 (2): 263-74.


A conductive pathway generated from fragments of the human red cell anion exchanger AE1., Parker MD, Young MT, Daly CM, Meech RW, Boron WF, Tanner MJ., J Physiol. May 15, 2007; 581 (Pt 1): 33-50.


The Xenopus FcR family demonstrates continually high diversification of paired receptors in vertebrate evolution., Guselnikov SV, Ramanayake T, Erilova AY, Mechetina LV, Najakshin AM, Robert J, Taranin AV., BMC Evol Biol. February 8, 2008; 8 148.                


Presence of aquaporin and V-ATPase on the contractile vacuole of Amoeba proteus., Nishihara E, Yokota E, Tazaki A, Orii H, Katsuhara M, Kataoka K, Igarashi H, Moriyama Y, Shimmen T, Sonobe S., Biol Cell. March 1, 2008; 100 (3): 179-88.


Structural signatures and membrane helix 4 in GLUT1: inferences from human blood-brain glucose transport mutants., Pascual JM, Wang D, Yang R, Shi L, Yang H, De Vivo DC., J Biol Chem. June 13, 2008; 283 (24): 16732-42.


Roles of ectodomain and transmembrane regions in ethanol and agonist action in purinergic P2X2 and P2X3 receptors., Asatryan L, Popova M, Woodward JJ, King BF, Alkana RL, Davies DL., Neuropharmacology. October 1, 2008; 55 (5): 835-43.


Cystic fibrosis transmembrane conductance regulator: using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore., Alexander C, Ivetac A, Liu X, Norimatsu Y, Serrano JR, Landstrom A, Sansom M, Dawson DC., Biochemistry. October 27, 2009; 48 (42): 10078-88.                


AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10., Ovens MJ, Davies AJ, Wilson MC, Murray CM, Halestrap AP., Biochem J. January 15, 2010; 425 (3): 523-30.              


The inhibition of monocarboxylate transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary protein., Ovens MJ, Manoharan C, Wilson MC, Murray CM, Halestrap AP., Biochem J. October 15, 2010; 431 (2): 217-25.              


The intracellular amino terminus plays a dominant role in desensitization of ATP-gated P2X receptor ion channels., Allsopp RC, Evans RJ., J Biol Chem. December 30, 2011; 286 (52): 44691-701.            


Effect of simultaneously replacing putative TM6 and TM12 of human NBCe1-A with those from NBCn1 on surface abundance in Xenopus oocytes., Chen LM, Qin X, Moss FJ, Liu Y, Boron WF., J Membr Biol. March 1, 2012; 245 (3): 131-40.


Arg188 in rice sucrose transporter OsSUT1 is crucial for substrate transport., Sun Y, Ward JM., BMC Biochem. November 21, 2012; 13 26.          


The SLC16 gene family - structure, role and regulation in health and disease., Halestrap AP., Mol Aspects Med. January 1, 2013; 34 (2-3): 337-49.


Both transmembrane domains of BK β1 subunits are essential to confer the normal phenotype of β1-containing BK channels., Kuntamallappanavar G, Toro L, Dopico AM., PLoS One. January 1, 2014; 9 (10): e109306.          

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