Papers associated with gabarap

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	Emamectin is a non-selective allosteric activator of nicotinic acetylcholine receptors and GABAA/C receptors., Xu X, Sepich C, Lukas RJ, Zhu G, Chang Y., Biochem Biophys Res Commun. May 13, 2016; 473 (4): 795-800.
	Potentiation of Gamma Aminobutyric Acid Receptors (GABAAR) by Ethanol: How Are Inhibitory Receptors Affected?, Förstera B, Castro PA, Moraga-Cid G, Aguayo LG., Front Cell Neurosci. May 6, 2016; 10 114.
	Correction for Inhibition Leads to an Allosteric Co-Agonist Model for Pentobarbital Modulation and Activation of α1β3γ2L GABAA Receptors., Ziemba AM, Forman SA., PLoS One. April 21, 2016; 11 (4): e0154031.
	GABAA receptor cysteinyl mutants and the ginkgo terpenoid lactones bilobalide and ginkgolides., Ng CC, Duke RK, Hinton T, Johnston GA., Eur J Pharmacol. April 15, 2016; 777 136-46.
	Dipicrylamine Modulates GABAρ1 Receptors through Interactions with Residues in the TM4 and Cys-Loop Domains., Limon A, Estrada-Mondragón A, Ruiz JM, Miledi R., Mol Pharmacol. April 1, 2016; 89 (4): 446-56.
	Potentiating effect of glabridin from Glycyrrhiza glabra on GABAA receptors., Hoffmann KM, Beltrán L, Ziemba PM, Hatt H, Gisselmann G., Biochem Biophys Rep. March 31, 2016; 6 197-202.
	Perturbation of Critical Prolines in Gloeobacter violaceus Ligand-gated Ion Channel (GLIC) Supports Conserved Gating Motions among Cys-loop Receptors., Rienzo M, Rocchi AR, Threatt SD, Dougherty DA, Lummis SC., J Biol Chem. March 18, 2016; 291 (12): 6272-80.
	Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels., Bertozzi C, Zimmermann I, Engeler S, Hilf RJ, Dutzler R., PLoS Biol. March 4, 2016; 14 (3): e1002393.
	Pharmacological induction of skin pigmentation unveils the neuroendocrine circuit regulated by light., Bertolesi GE, Vazhappilly ST, Hehr CL, McFarlane S., Pigment Cell Melanoma Res. March 1, 2016; 29 (2): 186-98.
	High and low GABA sensitivity α4β2δ GABAA receptors are expressed in Xenopus laevis oocytes with divergent stoichiometries., Hartiadi LY, Ahring PK, Chebib M, Absalom NL., Biochem Pharmacol. March 1, 2016; 103 98-108.
	γ-Aminobutyric Acid Type A Receptor Modulation by Etomidate Analogs., Pejo E, Santer P, Wang L, Dershwitz P, Husain SS, Raines DE., Anesthesiology. March 1, 2016; 124 (3): 651-63.
	A new chromanone derivative isolated from Hypericum lissophloeus (Hypericaceae) potentiates GABAA receptor currents in a subunit specific fashion., Crockett S, Baur R, Kunert O, Belaj F, Sigel E., Bioorg Med Chem. February 15, 2016; 24 (4): 681-5.
	Propofol and AZD3043 Inhibit Adult Muscle and Neuronal Nicotinic Acetylcholine Receptors Expressed in Xenopus Oocytes., Jonsson Fagerlund M, Krupp J, Dabrowski MA., Pharmaceuticals (Basel). February 6, 2016; 9 (1):
	Identification of an Inhibitory Alcohol Binding Site in GABAA ρ1 Receptors., Borghese CM, Ruiz CI, Lee US, Cullins MA, Bertaccini EJ, Trudell JR, Harris RA., ACS Chem Neurosci. January 20, 2016; 7 (1): 100-8.
	A Cysteine Substitution Probes β3H267 Interactions with Propofol and Other Potent Anesthetics in α1β3γ2L γ-Aminobutyric Acid Type A Receptors., Stern AT, Forman SA., Anesthesiology. January 1, 2016; 124 (1): 89-100.
	GABAA Receptor Modulation by Phenyl Ring Compounds Is Associated with a Water Solubility Cut-Off Value., Brosnan RJ, Pham TL., Pharmacology. January 1, 2016; 98 (1-2): 13-9.
	Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism., Chua HC, Christensen ET, Hoestgaard-Jensen K, Hartiadi LY, Ramzan I, Jensen AA, Absalom NL, Chebib M., PLoS One. January 1, 2016; 11 (6): e0157700.
	Structure-dependent inhibition of the human α1β2γ2 GABAA receptor by piperazine derivatives: A novel mode of action., Hondebrink L, Hermans EJ, Schmeink S, van Kleef RG, Meulenbelt J, Westerink RH., Neurotoxicology. December 1, 2015; 51 1-9.
	Contrasting actions of a convulsant barbiturate and its anticonvulsant enantiomer on the α1 β3 γ2L GABAA receptor account for their in vivo effects., Desai R, Savechenkov PY, Zolkowska D, Ge RL, Rogawski MA, Bruzik KS, Forman SA, Raines DE, Miller KW., J Physiol. November 15, 2015; 593 (22): 4943-61.
	Identification of the putative binding pocket of valerenic acid on GABAA receptors using docking studies and site-directed mutagenesis., Luger D, Poli G, Wieder M, Stadler M, Ke S, Ernst M, Hohaus A, Linder T, Seidel T, Langer T, Khom S, Hering S., Br J Pharmacol. November 1, 2015; 172 (22): 5403-13.
	The Direct Actions of GABA, 2'-Methoxy-6-Methylflavone and General Anaesthetics at β3γ2L GABAA Receptors: Evidence for Receptors with Different Subunit Stoichiometries., Chua HC, Absalom NL, Hanrahan JR, Viswas R, Chebib M., PLoS One. October 20, 2015; 10 (10): e0141359.
	Nitrogenated honokiol derivatives allosterically modulate GABAA receptors and act as strong partial agonists., Bernaskova M, Schoeffmann A, Schuehly W, Hufner A, Baburin I, Hering S., Bioorg Med Chem. October 15, 2015; 23 (20): 6757-62.
	A novel GABA(A) alpha 5 receptor inhibitor with therapeutic potential., Ling I, Mihalik B, Etherington LA, Kapus G, Pálvölgyi A, Gigler G, Kertész S, Gaál A, Pallagi K, Kiricsi P, Szabó É, Szénási G, Papp L, Hársing LG, Lévay G, Spedding M, Lambert JJ, Belelli D, Barkóczy J, Volk B, Simig G, Gacsályi I, Antoni FA., Eur J Pharmacol. October 5, 2015; 764 497-507.
	GABAA currents are decreased by IL-1β in epileptogenic tissue of patients with temporal lobe epilepsy: implications for ictogenesis., Roseti C, van Vliet EA, Cifelli P, Ruffolo G, Baayen JC, Di Castro MA, Bertollini C, Limatola C, Aronica E, Vezzani A, Palma E., Neurobiol Dis. October 1, 2015; 82 311-320.
	Mutational Analysis of the Putative High-Affinity Propofol Binding Site in Human β3 Homomeric GABAA Receptors., Eaton MM, Cao LQ, Chen Z, Franks NP, Evers AS, Akk G., Mol Pharmacol. October 1, 2015; 88 (4): 736-45.
	Interactions of L-3,5,3'-Triiodothyronine [corrected], Allopregnanolone, and Ivermectin with the GABAA Receptor: Evidence for Overlapping Intersubunit Binding Modes., Westergard T, Salari R, Martin JV, Brannigan G., PLoS One. September 4, 2015; 10 (9): e0139072.
	Direct evidence for GABAergic activity of Withania somnifera on mammalian ionotropic GABAA and GABAρ receptors., Candelario M, Cuellar E, Reyes-Ruiz JM, Darabedian N, Feimeng Z, Miledi R, Russo-Neustadt A, Limon A., J Ethnopharmacol. August 2, 2015; 171 264-72.
	A molecular characterization of the agonist binding site of a nematode cys-loop GABA receptor., Kaji MD, Kwaka A, Callanan MK, Nusrat H, Desaulniers JP, Forrester SG., Br J Pharmacol. August 1, 2015; 172 (15): 3737-47.
	Positive modulation of synaptic and extrasynaptic GABAA receptors by an antagonist of the high affinity benzodiazepine binding site., Middendorp SJ, Maldifassi MC, Baur R, Sigel E., Neuropharmacology. August 1, 2015; 95 459-67.
	A Multifaceted GABAA Receptor Modulator: Functional Properties and Mechanism of Action of the Sedative-Hypnotic and Recreational Drug Methaqualone (Quaalude)., Hammer H, Bader BM, Ehnert C, Bundgaard C, Bunch L, Hoestgaard-Jensen K, Schroeder OH, Bastlund JF, Gramowski-Voß A, Jensen AA., Mol Pharmacol. August 1, 2015; 88 (2): 401-20.
	Carbonic anhydrase inhibition by acetazolamide reduces in vitro epileptiform synchronization., Hamidi S, Avoli M., Neuropharmacology. August 1, 2015; 95 377-87.
	GABA signalling modulates plant growth by directly regulating the activity of plant-specific anion transporters., Ramesh SA, Tyerman SD, Xu B, Bose J, Kaur S, Conn V, Domingos P, Ullah S, Wege S, Shabala S, Feijó JA, Ryan PR, Gilliham M., Nat Commun. July 29, 2015; 6 7879.
	Re-engineering a neuroprotective, clinical drug as a procognitive agent with high in vivo potency and with GABAA potentiating activity for use in dementia., Luo J, Lee SH, VandeVrede L, Qin Z, Piyankarage S, Tavassoli E, Asghodom RT, Ben Aissa M, Fà M, Arancio O, Yue L, Pepperberg DR, Thatcher GR., BMC Neurosci. June 19, 2015; 16 67.
	Role for the propofol hydroxyl in anesthetic protein target molecular recognition., Woll KA, Weiser BP, Liang Q, Meng T, McKinstry-Wu A, Pinch B, Dailey WP, Gao WD, Covarrubias M, Eckenhoff RG., ACS Chem Neurosci. June 17, 2015; 6 (6): 927-35.
	Identification of amino acids involved in histamine potentiation of GABA A receptors., Thiel U, Platt SJ, Wolf S, Hatt H, Gisselmann G., Front Pharmacol. May 26, 2015; 6 106.
	The desensitization gate of inhibitory Cys-loop receptors., Gielen M, Thomas P, Smart TG., Nat Commun. April 20, 2015; 6 6829.
	Oxytocin prevents ethanol actions at δ subunit-containing GABAA receptors and attenuates ethanol-induced motor impairment in rats., Bowen MT, Peters ST, Absalom N, Chebib M, Neumann ID, McGregor IS., Proc Natl Acad Sci U S A. March 10, 2015; 112 (10): 3104-9.
	Pharmacological characterisation of murine α4β1δ GABAA receptors expressed in Xenopus oocytes., Villumsen IS, Wellendorph P, Smart TG., BMC Neurosci. March 5, 2015; 16 8.
	MmTX1 and MmTX2 from coral snake venom potently modulate GABAA receptor activity., Rosso JP, Schwarz JR, Diaz-Bustamante M, Céard B, Gutiérrez JM, Kneussel M, Pongs O, Bosmans F, Bougis PE., Proc Natl Acad Sci U S A. February 24, 2015; 112 (8): E891-900.
	GABAA α5 subunit-containing receptors do not contribute to reversal of inflammatory-induced spinal sensitization as indicated by the unique selectivity profile of the GABAA receptor allosteric modulator NS16085., de Lucas AG, Ahring PK, Larsen JS, Rivera-Arconada I, Lopez-Garcia JA, Mirza NR, Munro G., Biochem Pharmacol. February 1, 2015; 93 (3): 370-9.
	Metal-assisted synthesis of unsymmetrical magnolol and honokiol analogs and their biological assessment as GABAA receptor ligands., Rycek L, Puthenkalam R, Schnürch M, Ernst M, Mihovilovic MD., Bioorg Med Chem Lett. January 15, 2015; 25 (2): 400-3.
	Inhibitory effects of insulin on GABAA currents modulated by the GABAA alpha subunit., Williams DB., J Recept Signal Transduct Res. January 1, 2015; 35 (6): 516-22.
	The Differential Effects of Resveratrol and trans-ε-Viniferin on the GABA-Induced Current in GABAA Receptor Subtypes Expressed in Xenopus Laevis Oocytes., Groundwater PW, Hamid K, Ng I, Tallapragada VJ, Hibbs DE, Hanrahan J., J Pharm Pharm Sci. January 1, 2015; 18 (4): 328-38.
	Structural analogues of the natural products magnolol and honokiol as potent allosteric potentiators of GABA(A) receptors., Fuchs A, Baur R, Schoeder C, Sigel E, Müller CE., Bioorg Med Chem. December 15, 2014; 22 (24): 6908-17.
	Probing α4βδ GABAA receptor heterogeneity: differential regional effects of a functionally selective α4β1δ/α4β3δ receptor agonist on tonic and phasic inhibition in rat brain., Hoestgaard-Jensen K, Dalby NO, Krall J, Hammer H, Krogsgaard-Larsen P, Frølund B, Jensen AA., J Neurosci. December 3, 2014; 34 (49): 16256-72.
	The neurosteroid 5β-pregnan-3α-ol-20-one enhances actions of etomidate as a positive allosteric modulator of α1β2γ2L GABAA receptors., Li P, Bracamontes JR, Manion BD, Mennerick S, Steinbach JH, Evers AS, Akk G., Br J Pharmacol. December 1, 2014; 171 (23): 5446-57.
	Identification of dehydroabietc acid from Boswellia thurifera resin as a positive GABAA receptor modulator., Rueda DC, Raith M, De Mieri M, Schöffmann A, Hering S, Hamburger M., Fitoterapia. December 1, 2014; 99 28-34.
	An atypical residue in the pore of Varroa destructor GABA-activated RDL receptors affects picrotoxin block and thymol modulation., Price KL, Lummis SC., Insect Biochem Mol Biol. December 1, 2014; 55 19-25.
	Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation., Brosnan RJ, Pham TL., BMC Pharmacol Toxicol. November 19, 2014; 15 62.
	Benzodiazepine modulation of homomeric GABAAρ1 receptors: differential effects of diazepam and 4'-chlorodiazepam., Beltrán González AN, Pomata PE, Goutman JD, Gasulla J, Chebib M, Calvo DJ., Eur J Pharmacol. November 15, 2014; 743 24-30.

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