Papers associated with gabarap

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	Benzodiazepines modulate GABAA receptors by regulating the preactivation step after GABA binding., Gielen MC, Lumb MJ, Smart TG., J Neurosci. April 25, 2012; 32 (17): 5707-15.
	HPLC-based activity profiling--discovery of sanggenons as GABAA receptor modulators in the traditional Chinese drug Sang bai pi (Morus alba root bark)., Kim HJ, Baburin I, Zaugg J, Ebrahimi SN, Hering S, Hamburger M., Planta Med. March 1, 2012; 78 (5): 440-7.
	Structural link between γ-aminobutyric acid type A (GABAA) receptor agonist binding site and inner β-sheet governs channel activation and allosteric drug modulation., Venkatachalan SP, Czajkowski C., J Biol Chem. February 24, 2012; 287 (9): 6714-24.
	Mutations in the GABAA receptor that mimic the allosteric ligand etomidate., Forman SA, Stewart D., Methods Mol Biol. January 1, 2012; 796 317-33.
	The biochemical anatomy of cortical inhibitory synapses., Heller EA, Zhang W, Selimi F, Earnheart JC, Ślimak MA, Santos-Torres J, Ibañez-Tallon I, Aoki C, Chait BT, Heintz N., PLoS One. January 1, 2012; 7 (6): e39572.
	Effects of Ginsenoside Metabolites on GABAA Receptor-Mediated Ion Currents., Lee BH, Choi SH, Shin TJ, Hwang SH, Kang J, Kim HJ, Kim BJ, Nah SY., J Ginseng Res. January 1, 2012; 36 (1): 55-60.
	Modulation of human GABAA receptor function: a novel mode of action of drugs of abuse., Hondebrink L, Meulenbelt J, van Kleef RG, van den Berg M, Westerink RH., Neurotoxicology. December 1, 2011; 32 (6): 823-7.
	Insights into structure-activity relationship of GABAA receptor modulating coumarins and furanocoumarins., Singhuber J, Baburin I, Ecker GF, Kopp B, Hering S., Eur J Pharmacol. October 1, 2011; 668 (1-2): 57-64.
	Cysteine modification reveals which subunits form the ligand binding site in human heteromeric 5-HT3AB receptors., Thompson AJ, Price KL, Lummis SC., J Physiol. September 1, 2011; 589 (17): 4243-57.
	Modulation of GABAA-receptors by honokiol and derivatives: subtype selectivity and structure-activity relationship., Taferner B, Schuehly W, Huefner A, Baburin I, Wiesner K, Ecker GF, Hering S., J Med Chem. August 11, 2011; 54 (15): 5349-61.
	Different residues in the GABAA receptor benzodiazepine binding pocket mediate benzodiazepine efficacy and binding., Morlock EV, Czajkowski C., Mol Pharmacol. July 1, 2011; 80 (1): 14-22.
	Occupation of either site for the neurosteroid allopregnanolone potentiates the opening of the GABAA receptor induced from either transmitter binding site., Bracamontes J, McCollum M, Esch C, Li P, Ann J, Steinbach JH, Akk G., Mol Pharmacol. July 1, 2011; 80 (1): 79-86.
	HPLC-based activity profiling for GABAA receptor modulators from the traditional Chinese herbal drug Kushen (Sophora flavescens root)., Yang X, Baburin I, Plitzko I, Hering S, Hamburger M., Mol Divers. May 1, 2011; 15 (2): 361-72.
	HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes., Zaugg J, Eickmeier E, Rueda DC, Hering S, Hamburger M., Fitoterapia. April 1, 2011; 82 (3): 434-40.
	Cloning and characterization of GABAA α subunits and GABAB subunits in Xenopus laevis during development., Kaeser GE, Rabe BA, Saha MS., Dev Dyn. April 1, 2011; 240 (4): 862-73.
	The GABAA receptor alpha+beta- interface: a novel target for subtype selective drugs., Ramerstorfer J, Furtmüller R, Sarto-Jackson I, Varagic Z, Sieghart W, Ernst M., J Neurosci. January 19, 2011; 31 (3): 870-7.
	Ginkgolide B and bilobalide block the pore of the 5-HT₃receptor at a location that overlaps the picrotoxin binding site., Thompson AJ, Jarvis GE, Duke RK, Johnston GA, Lummis SC., Neuropharmacology. January 1, 2011; 60 (2-3): 488-95.
	A closer look at the high affinity benzodiazepine binding site on GABAA receptors., Sigel E, Lüscher BP., Curr Top Med Chem. January 1, 2011; 11 (2): 241-6.
	Ligand- and subunit-specific conformational changes in the ligand-binding domain and the TM2-TM3 linker of {alpha}1 {beta}2 {gamma}2 GABAA receptors., Wang Q, Pless SA, Lynch JW., J Biol Chem. December 17, 2010; 285 (51): 40373-86.
	A transmembrane amino acid in the GABAA receptor β2 subunit critical for the actions of alcohols and anesthetics., McCracken ML, Borghese CM, Trudell JR, Harris RA., J Pharmacol Exp Ther. December 1, 2010; 335 (3): 600-6.
	PCB-47, PBDE-47, and 6-OH-PBDE-47 differentially modulate human GABAA and alpha4beta2 nicotinic acetylcholine receptors., Hendriks HS, Antunes Fernandes EC, Bergman A, van den Berg M, Westerink RH., Toxicol Sci. December 1, 2010; 118 (2): 635-42.
	A residue close to α1 loop F disrupts modulation of GABAA receptors by benzodiazepines while their binding is maintained., Baur R, Lüscher BP, Richter L, Sigel E., J Neurochem. December 1, 2010; 115 (6): 1478-85.
	Benzodiazepine modulation of the rat GABAA receptor α4β3γ2L subtype expressed in Xenopus oocytes., You H, Kozuska JL, Paulsen IM, Dunn SM., Neuropharmacology. November 1, 2010; 59 (6): 527-33.
	Activation and potentiation of human GABAA receptors by non-dioxin-like PCBs depends on chlorination pattern., Antunes Fernandes EC, Hendriks HS, van Kleef RG, Reniers A, Andersson PL, van den Berg M, Westerink RH., Toxicol Sci. November 1, 2010; 118 (1): 183-90.
	GABAergic circuits control stimulus-instructed receptive field development in the optic tectum., Richards BA, Voss OP, Akerman CJ., Nat Neurosci. September 1, 2010; 13 (9): 1098-106.
	Valerenic acid derivatives as novel subunit-selective GABAA receptor ligands - in vitro and in vivo characterization., Khom S, Strommer B, Ramharter J, Schwarz T, Schwarzer C, Erker T, Ecker GF, Mulzer J, Hering S., Br J Pharmacol. September 1, 2010; 161 (1): 65-78.
	m-Azipropofol (AziPm) a photoactive analogue of the intravenous general anesthetic propofol., Hall MA, Xi J, Lor C, Dai S, Pearce R, Dailey WP, Eckenhoff RG., J Med Chem. August 12, 2010; 53 (15): 5667-75.
	Fragrant dioxane derivatives identify beta1-subunit-containing GABAA receptors., Sergeeva OA, Kletke O, Kragler A, Poppek A, Fleischer W, Schubring SR, Görg B, Haas HL, Zhu XR, Lübbert H, Gisselmann G, Hatt H., J Biol Chem. July 30, 2010; 285 (31): 23985-93.
	Agonist function of the recombinant alpha 4 beta 3 delta GABAA receptor is dependent on the human and rat variants of the alpha 4-subunit., Wang MD, Rahman M, Johansson IM, Bäckström T., Clin Exp Pharmacol Physiol. July 1, 2010; 37 (7): 662-9.
	Diversity of structure and function of alpha1alpha6beta3delta GABAA receptors: comparison with alpha1beta3delta and alpha6beta3delta receptors., Baur R, Kaur KH, Sigel E., J Biol Chem. June 4, 2010; 285 (23): 17398-405.
	Structurally diverse amphiphiles exhibit biphasic modulation of GABAA receptors: similarities and differences with neurosteroid actions., Chisari M, Shu HJ, Taylor A, Steinbach JH, Zorumski CF, Mennerick S., Br J Pharmacol. May 1, 2010; 160 (1): 130-41.
	A synthetic 18-norsteroid distinguishes between two neuroactive steroid binding sites on GABAA receptors., Evers AS, Chen ZW, Manion BD, Han M, Jiang X, Darbandi-Tonkabon R, Kable T, Bracamontes J, Zorumski CF, Mennerick S, Steinbach JH, Covey DF., J Pharmacol Exp Ther. May 1, 2010; 333 (2): 404-13.
	Molecular characterization of agonists that bind to an insect GABA receptor., McGonigle I, Lummis SC., Biochemistry. April 6, 2010; 49 (13): 2897-902.
	Novel positive allosteric modulators of GABAA receptors: do subtle differences in activity at alpha1 plus alpha5 versus alpha2 plus alpha3 subunits account for dissimilarities in behavioral effects in rats?, Savić MM, Majumder S, Huang S, Edwankar RV, Furtmüller R, Joksimović S, Clayton T, Ramerstorfer J, Milinković MM, Roth BL, Sieghart W, Cook JM., Prog Neuropsychopharmacol Biol Psychiatry. March 17, 2010; 34 (2): 376-86.
	Limiting activity at beta1-subunit-containing GABAA receptor subtypes reduces ataxia., Gee KW, Tran MB, Hogenkamp DJ, Johnstone TB, Bagnera RE, Yoshimura RF, Huang JC, Belluzzi JD, Whittemore ER., J Pharmacol Exp Ther. March 1, 2010; 332 (3): 1040-53.
	Diverse voltage-sensitive dyes modulate GABAA receptor function., Mennerick S, Chisari M, Shu HJ, Taylor A, Vasek M, Eisenman LN, Zorumski CF., J Neurosci. February 24, 2010; 30 (8): 2871-9.
	About a snail, a toad, and rodents: animal models for adaptation research., Roubos EW, Jenks BG, Xu L, Kuribara M, Scheenen WJ, Kozicz T., Front Endocrinol (Lausanne). January 1, 2010; 1 4.
	Gamma-amino butyric acid type A receptor mutations at beta2N265 alter etomidate efficacy while preserving basal and agonist-dependent activity., Desai R, Ruesch D, Forman SA., Anesthesiology. October 1, 2009; 111 (4): 774-84.
	Photodynamic effects of steroid-conjugated fluorophores on GABAA receptors., Shu HJ, Eisenman LN, Wang C, Bandyopadhyaya AK, Krishnan K, Taylor A, Benz AM, Manion B, Evers AS, Covey DF, Zorumski CF, Mennerick S., Mol Pharmacol. October 1, 2009; 76 (4): 754-65.
	Inhibitory transmission in locus coeruleus neurons expressing GABAA receptor epsilon subunit has a number of unique properties., Belujon P, Baufreton J, Grandoso L, Boué-Grabot E, Batten TF, Ugedo L, Garret M, Taupignon AI., J Neurophysiol. October 1, 2009; 102 (4): 2312-25.
	The influence of neuroactive steroid lipophilicity on GABAA receptor modulation: evidence for a low-affinity interaction., Chisari M, Eisenman LN, Krishnan K, Bandyopadhyaya AK, Wang C, Taylor A, Benz A, Covey DF, Zorumski CF, Mennerick S., J Neurophysiol. August 1, 2009; 102 (2): 1254-64.
	Unanticipated structural and functional properties of delta-subunit-containing GABAA receptors., Kaur KH, Baur R, Sigel E., J Biol Chem. March 20, 2009; 284 (12): 7889-96.
	GABA-induced intersubunit conformational movement in the GABAA receptor alpha 1M1-beta 2M3 transmembrane subunit interface: experimental basis for homology modeling of an intravenous anesthetic binding site., Bali M, Jansen M, Akabas MH., J Neurosci. March 11, 2009; 29 (10): 3083-92.
	Oxcarbazepine, not its active metabolite, potentiates GABAA activation and aggravates absence seizures., Zheng T, Clarke AL, Morris MJ, Reid CA, Petrou S, O'Brien TJ., Epilepsia. January 1, 2009; 50 (1): 83-7.
	Distinct structural changes in the GABAA receptor elicited by pentobarbital and GABA., Muroi Y, Theusch CM, Czajkowski C, Jackson MB., Biophys J. January 1, 2009; 96 (2): 499-509.
	Tryptophan mutations at azi-etomidate photo-incorporation sites on alpha1 or beta2 subunits enhance GABAA receptor gating and reduce etomidate modulation., Stewart D, Desai R, Cheng Q, Liu A, Forman SA., Mol Pharmacol. December 1, 2008; 74 (6): 1687-95.
	Structural determinants for antagonist pharmacology that distinguish the rho1 GABAC receptor from GABAA receptors., Zhang J, Xue F, Chang Y., Mol Pharmacol. October 1, 2008; 74 (4): 941-51.
	Adenosine receptor antagonists alter the stability of human epileptic GABAA receptors., Roseti C, Martinello K, Fucile S, Piccari V, Mascia A, Di Gennaro G, Quarato PP, Manfredi M, Esposito V, Cantore G, Arcella A, Simonato M, Fredholm BB, Limatola C, Miledi R, Eusebi F., Proc Natl Acad Sci U S A. September 30, 2008; 105 (39): 15118-23.
	Covalent modification of GABAA receptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs., Baur R, Tan KR, Lüscher BP, Gonthier A, Goeldner M, Sigel E., J Neurochem. September 1, 2008; 106 (6): 2353-63.
	Synthesis of GABAA receptor agonists and evaluation of their alpha-subunit selectivity and orientation in the GABA binding site., Jansen M, Rabe H, Strehle A, Dieler S, Debus F, Dannhardt G, Akabas MH, Lüddens H., J Med Chem. August 14, 2008; 51 (15): 4430-48.

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