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Summary Expression Phenotypes Gene Literature (43) GO Terms (0) Nucleotides (21) Proteins (21) Interactants (593) Wiki
XB-GENEPAGE-29072347

Papers associated with axin2



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Enhancement of neural crest formation by mechanical force in Xenopus development., Kaneshima T, Ogawa M, Yamamoto T, Tsuboyama Y, Miyata Y, Kotani T, Okajima T, Michiue T., Int J Dev Biol. January 1, 2024; 68 (1): 25-37.              

The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E., Nat Commun. October 5, 2023; 14 (1): 6173.                                

CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping., Naert T, Tulkens D, Van Nieuwenhuysen T, Przybyl J, Demuynck S, van de Rijn M, Al-Jazrawe M, Alman BA, Coucke PJ, De Leeneer K, Vanhove C, Savvides SN, Creytens D, Vleminckx K, Vleminckx K., Proc Natl Acad Sci U S A. November 23, 2021; 118 (47):                             

The Actin-Family Protein Arp4 Is a Novel Suppressor for the Formation and Functions of Nuclear F-Actin., Yamazaki S, Gerhold C, Yamamoto K, Ueno Y, Grosse R, Miyamoto K, Harata M., Cells. March 19, 2020; 9 (3):           

The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer., Chang LS, Kim M, Glinka A, Reinhard C, Niehrs C., Elife. January 14, 2020; 9                                                                                               

Pathogenic FAM83G palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signalling., Wu KZL, Jones RA, Tachie-Menson T, Macartney TJ, Wood NT, Varghese J, Gourlay R, Soares RF, Smith JC, Sapkota GP., Wellcome Open Res. January 1, 2019; 4 133.          

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.                                

Two-Element Transcriptional Regulation in the Canonical Wnt Pathway., Kim K, Cho J, Hilzinger TS, Nunns H, Liu A, Ryba BE, Goentoro L., Curr Biol. August 7, 2017; 27 (15): 2357-2364.e5.                

Genome-wide identification of Wnt/β-catenin transcriptional targets during Xenopus gastrulation., Kjolby RAS, Harland RM., Dev Biol. June 15, 2017; 426 (2): 165-175.                                    

High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Michiue T, Yamamoto T, Yasuoka Y, Goto T, Ikeda T, Nagura K, Nakayama T, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 270-290.                  

An Epha4/Sipa1l3/Wnt pathway regulates eye development and lens maturation., Rothe M, Kanwal N, Dietmann P, Seigfried FA, Hempel A, Schütz D, Reim D, Engels R, Linnemann A, Schmeisser MJ, Bockmann J, Kühl M, Boeckers TM, Kühl SJ., Development. January 15, 2017; 144 (2): 321-333.                              

WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis., Nalesso G, Thomas BL, Sherwood JC, Yu J, Addimanda O, Eldridge SE, Thorup AS, Dale L, Schett G, Zwerina J, Eltawil N, Pitzalis C, Dell'Accio F., Ann Rheum Dis. January 1, 2017; 76 (1): 218-226.              

A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification., Rankin SA, Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM, Shannon JM, Zorn AM., Cell Rep. June 28, 2016; 16 (1): 66-78.                                              

Lens regeneration from the cornea requires suppression of Wnt/β-catenin signaling., Hamilton PW, Sun Y, Henry JJ., Exp Eye Res. April 1, 2016; 145 206-215.          

Noggin4 is a long-range inhibitor of Wnt8 signalling that regulates head development in Xenopus laevis., Eroshkin FM, Nesterenko AM, Borodulin AV, Martynova NY, Ermakova GV, Gyoeva FK, Orlov EE, Belogurov AA, Lukyanov KA, Bayramov AV, Zaraisky AG., Sci Rep. January 22, 2016; 6 23049.                                                            

Regulation of nuclear-cytoplasmic shuttling and function of Family with sequence similarity 13, member A (Fam13a), by B56-containing PP2As and Akt., Jin Z, Chung JW, Mei W, Strack S, He C, Lau GW, Yang J., Mol Biol Cell. March 15, 2015; 26 (6): 1160-73.                  

Early development of the neural plate: new roles for apoptosis and for one of its main effectors caspase-3., Juraver-Geslin HA, Durand BC., Genesis. February 1, 2015; 53 (2): 203-24.          

CNBP modulates the transcription of Wnt signaling pathway components., Margarit E, Armas P, García Siburu N, Calcaterra NB., Biochim Biophys Acta. November 1, 2014; 1839 (11): 1151-60.                

In vivo analysis of formation and endocytosis of the Wnt/β-catenin signaling complex in zebrafish embryos., Hagemann AI, Kurz J, Kauffeld S, Chen Q, Reeves PM, Weber S, Schindler S, Davidson G, Kirchhausen T, Scholpp S., J Cell Sci. September 15, 2014; 127 (Pt 18): 3970-82.                  

WLS retrograde transport to the endoplasmic reticulum during Wnt secretion., Yu J, Chia J, Canning CA, Jones CM, Bard FA, Virshup DM., Dev Cell. May 12, 2014; 29 (3): 277-91.  

Polarized Wnt signaling regulates ectodermal cell fate in Xenopus., Huang YL, Niehrs C., Dev Cell. April 28, 2014; 29 (2): 250-7.                  

Selective nuclear export of specific classes of mRNA from mammalian nuclei is promoted by GANP., Wickramasinghe VO, Andrews R, Ellis P, Langford C, Gurdon JB, Stewart M, Venkitaraman AR, Laskey RA., Nucleic Acids Res. April 1, 2014; 42 (8): 5059-71.            

Pax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers., Plouhinec JL, Roche DD, Pegoraro C, Figueiredo AL, Maczkowiak F, Brunet LJ, Milet C, Vert JP, Pollet N, Harland RM, Monsoro-Burq AH., Dev Biol. February 15, 2014; 386 (2): 461-72.                                            

Syndecan-4 inhibits Wnt/β-catenin signaling through regulation of low-density-lipoprotein receptor-related protein (LRP6) and R-spondin 3., Astudillo P, Carrasco H, Larraín J., Int J Biochem Cell Biol. January 1, 2014; 46 103-12.            

RAB8B is required for activity and caveolar endocytosis of LRP6., Demir K, Kirsch N, Beretta CA, Erdmann G, Ingelfinger D, Moro E, Argenton F, Carl M, Niehrs C, Boutros M., Cell Rep. September 26, 2013; 4 (6): 1224-34.                    

GREM1, FRZB and DKK1 mRNA levels correlate with osteoarthritis and are regulated by osteoarthritis-associated factors., Leijten JC, Bos SD, Landman EB, Georgi N, Jahr H, Meulenbelt I, Post JN, van Blitterswijk CA, Karperien M., Arthritis Res Ther. September 19, 2013; 15 (5): R126.            

The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling., Wang F, Hu W, Xian J, Ohnuma S, Brenton JD., Dev Biol. July 1, 2013; 379 (1): 16-27.                            

Precise regulation of porcupine activity is required for physiological Wnt signaling., Proffitt KD, Virshup DM., J Biol Chem. October 5, 2012; 287 (41): 34167-78.              

A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice., Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S., Cancer Res. June 1, 2012; 72 (11): 2822-32.

Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells., Evans AL, Faial T, Gilchrist MJ, Down T, Vallier L, Pedersen RA, Wardle FC, Smith JC., PLoS One. January 1, 2012; 7 (3): e33346.              

Transcription factor Zic2 inhibits Wnt/β-catenin protein signaling., Pourebrahim R, Houtmeyers R, Ghogomu S, Janssens S, Thelie A, Tran HT, Langenberg T, Vleminckx K, Vleminckx K, Bellefroid E, Cassiman JJ, Tejpar S., J Biol Chem. October 28, 2011; 286 (43): 37732-40.          

WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways., Nalesso G, Sherwood J, Bertrand J, Pap T, Ramachandran M, De Bari C, Pitzalis C, Dell'accio F., J Cell Biol. May 2, 2011; 193 (3): 551-64.              

Barhl2 limits growth of the diencephalic primordium through Caspase3 inhibition of beta-catenin activation., Juraver-Geslin HA, Ausseil JJ, Wassef M, Durand BC., Proc Natl Acad Sci U S A. February 8, 2011; 108 (6): 2288-93.                    

Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth., Waaler J, Machon O, von Kries JP, Wilson SR, Lundenes E, Wedlich D, Gradl D, Paulsen JE, Machonova O, Dembinski JL, Dinh H, Krauss S., Cancer Res. January 1, 2011; 71 (1): 197-205.

Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction., Wang Y, Fu Y, Gao L, Zhu G, Liang J, Gao C, Huang B, Fenger U, Niehrs C, Chen YG, Chen YG, Wu W., J Biol Chem. April 2, 2010; 285 (14): 10890-901.                            

Xenopus axin-related protein: a link between its centrosomal localization and function in the Wnt/beta-catenin pathway., Alexandrova EM, Sokol SY., Dev Dyn. January 1, 2010; 239 (1): 261-70.            

Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis., Karner CM, Chirumamilla R, Aoki S, Igarashi P, Wallingford JB, Carroll TJ., Nat Genet. July 1, 2009; 41 (7): 793-9.          

Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL., Chitalia VC, Foy RL, Bachschmid MM, Zeng L, Panchenko MV, Zhou MI, Bharti A, Seldin DC, Lecker SH, Dominguez I, Cohen HT., Nat Cell Biol. October 1, 2008; 10 (10): 1208-16.        

LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin., Cselenyi CS, Jernigan KK, Tahinci E, Thorne CA, Lee LA, Lee E, Lee E., Proc Natl Acad Sci U S A. June 10, 2008; 105 (23): 8032-7.        

Investigation of Frizzled-5 during embryonic neural development in mouse., Burns CJ, Zhang J, Brown EC, Van Bibber AM, Van Es J, Clevers H, Ishikawa TO, Taketo MM, Vetter ML, Fuhrmann S., Dev Dyn. June 1, 2008; 237 (6): 1614-26.

NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)., Yamada M, Ohnishi J, Ohkawara B, Iemura S, Satoh K, Hyodo-Miura J, Kawachi K, Natsume T, Shibuya H., J Biol Chem. July 28, 2006; 281 (30): 20749-20760.                    

Wnt pathway mutations selected by optimal beta-catenin signaling for tumorigenesis., Cho KH, Baek S, Sung MH., FEBS Lett. June 26, 2006; 580 (15): 3665-70.

Identification and characterization of rat Dact1 and Dact2 genes in silico., Katoh M., Int J Mol Med. June 1, 2005; 15 (6): 1045-9.

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