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Summary Expression Phenotypes Gene Literature (72) GO Terms (27) Nucleotides (104) Proteins (54) Interactants (583) Wiki
XB-GENEPAGE-482643

Papers associated with gli1



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Gli1 is a target of Sonic hedgehog that induces ventral neural tube development., Lee J, Platt KA, Censullo P, Ruiz i Altaba A., Development. July 1, 1997; 124 (13): 2537-52.                  

Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours., Dahmane N, Lee J, Lee J, Robins P, Heller P, Ruiz i Altaba A., Nature. October 23, 1997; 389 (6653): 876-81.

Expression profile of Gli family members and Shh in normal and mutant mouse limb development., Büscher D, Rüther U., Dev Dyn. January 1, 1998; 211 (1): 88-96.

Combinatorial Gli gene function in floor plate and neuronal inductions by Sonic hedgehog., Ruiz i Altaba A., Development. June 1, 1998; 125 (12): 2203-12.

Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice., Ding Q, Motoyama J, Gasca S, Mo R, Sasaki H, Rossant J, Hui CC., Development. July 1, 1998; 125 (14): 2533-43.

The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants., Hardcastle Z, Mo R, Hui CC, Sharpe PT., Development. August 1, 1998; 125 (15): 2803-11.

Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus., Motoyama J, Liu J, Mo R, Ding Q, Post M, Hui CC., Nat Genet. September 1, 1998; 20 (1): 54-7.

Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3., Dai P, Akimaru H, Tanaka Y, Maekawa T, Nakafuku M, Ishii S., J Biol Chem. March 19, 1999; 274 (12): 8143-52.

Gli proteins encode context-dependent positive and negative functions: implications for development and disease., Ruiz i Altaba A., Development. June 1, 1999; 126 (14): 3205-16.                

Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators., Pearse RV, Collier LS, Scott MP, Tabin CJ., Dev Biol. August 15, 1999; 212 (2): 323-36.

Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling., Sasaki H, Nishizaki Y, Hui C, Nakafuku M, Kondoh H., Development. September 1, 1999; 126 (17): 3915-24.

Neuralization of the Xenopus embryo by inhibition of p300/ CREB-binding protein function., Kato Y, Shi Y, Shi Y, He X., J Neurosci. November 1, 1999; 19 (21): 9364-73.          

Distinct and regulated activities of human Gli proteins in Drosophila., von Mering C, Basler K., Curr Biol. November 18, 1999; 9 (22): 1319-22.

Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation., Park HL, Bai C, Platt KA, Matise MP, Beeghly A, Hui CC, Nakashima M, Joyner AL., Development. April 1, 2000; 127 (8): 1593-605.

Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites., Borycki A, Brown AM, Emerson CP., Development. May 1, 2000; 127 (10): 2075-87.

Regulation of gli activity by all-trans retinoic acid in mouse keratinocytes., Goyette P, Allan D, Peschard P, Chen CF, Wang W, Lohnes D., Cancer Res. October 1, 2000; 60 (19): 5386-9.

Gli2 functions in FGF signaling during antero-posterior patterning., Brewster R, Mullor JL, Ruiz i Altaba A., Development. October 1, 2000; 127 (20): 4395-405.            

Zic3 is involved in the left-right specification of the Xenopus embryo., Kitaguchi T, Nagai T, Nakata K, Aruga J, Mikoshiba K., Development. November 1, 2000; 127 (22): 4787-95.              

Xrel3 is required for head development in Xenopus laevis., Lake BB, Ford R, Kao KR., Development. January 1, 2001; 128 (2): 263-73.

Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins., Mizugishi K, Aruga J, Nakata K, Mikoshiba K., J Biol Chem. January 19, 2001; 276 (3): 2180-8.

Identification of NKL, a novel Gli-Kruppel zinc-finger protein that promotes neuronal differentiation., Lamar E, Kintner C, Goulding M., Development. April 1, 2001; 128 (8): 1335-46.              

Expression pattern of Irx1 and Irx2 during mouse digit development., Zülch A, Becker MB, Gruss P., Mech Dev. August 1, 2001; 106 (1-2): 159-62.

Irx1 and Irx2 expression in early lung development., Becker MB, Zülch A, Bosse A, Gruss P., Mech Dev. August 1, 2001; 106 (1-2): 155-8.

Gli1 can rescue the in vivo function of Gli2., Bai CB, Joyner AL., Development. December 1, 2001; 128 (24): 5161-72.

Conserved expression control and shared activity between cognate T-box genes Tbx2 and Tbx3 in connection with Sonic hedgehog signaling during Xenopus eye development., Takabatake Y, Takabatake T, Sasagawa S, Takeshima K., Dev Growth Differ. August 1, 2002; 44 (4): 257-71.              

A novel function for Hedgehog signalling in retinal pigment epithelium differentiation., Perron M, Boy S, Amato MA, Viczian A, Koebernick K, Pieler T, Harris WA., Development. April 1, 2003; 130 (8): 1565-77.                                  

Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development., Karlstrom RO, Tyurina OV, Kawakami A, Nishioka N, Talbot WS, Sasaki H, Schier AF., Development. April 1, 2003; 130 (8): 1549-64.

The amino-terminal region of Gli3 antagonizes the Shh response and acts in dorsoventral fate specification in the developing spinal cord., Meyer NP, Roelink H., Dev Biol. May 15, 2003; 257 (2): 343-55.

Expression profile of Xenopus banded hedgehog, a homolog of mouse Indian hedgehog, is related to the late development of endochondral ossification in Xenopus laevis., Moriishi T, Shibata Y, Tsukazaki T, Yamaguchi A., Biochem Biophys Res Commun. March 25, 2005; 328 (4): 867-73.

The pro-apoptotic activity of a vertebrate Bar-like homeobox gene plays a key role in patterning the Xenopus neural plate by limiting the number of chordin- and shh-expressing cells., Offner N, Duval N, Jamrich M, Durand B., Development. April 1, 2005; 132 (8): 1807-18.          

Cooperative requirement of the Gli proteins in neurogenesis., Nguyen V, Chokas AL, Stecca B, Ruiz i Altaba A., Development. July 1, 2005; 132 (14): 3267-79.                      

Dual degradation signals control Gli protein stability and tumor formation., Huntzicker EG, Estay IS, Zhen H, Lokteva LA, Jackson PK, Oro AE., Genes Dev. February 1, 2006; 20 (3): 276-81.

Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase., Koide T, Hayata T, Cho KW., Development. June 1, 2006; 133 (12): 2395-405.                

Suppressing Wnt signaling by the hedgehog pathway through sFRP-1., He J, Sheng T, Stelter AA, Li C, Zhang X, Sinha M, Luxon BA, Xie J., J Biol Chem. November 24, 2006; 281 (47): 35598-602.

PP2A:B56epsilon is required for eye induction and eye field separation., Rorick AM, Mei W, Liette NL, Phiel C, El-Hodiri HM, Yang J., Dev Biol. February 15, 2007; 302 (2): 477-93.                  

Correlation between Shh expression and DNA methylation status of the limb-specific Shh enhancer region during limb regeneration in amphibians., Yakushiji N, Suzuki M, Satoh A, Sagai T, Shiroishi T, Kobayashi H, Sasaki H, Ide H, Tamura K, Tamura K., Dev Biol. December 1, 2007; 312 (1): 171-82.  

Effects of activation of hedgehog signaling on patterning, growth, and differentiation in Xenopus froglet limb regeneration., Yakushiji N, Suzuki M, Satoh A, Ide H, Tamura K, Tamura K., Dev Dyn. August 1, 2009; 238 (8): 1887-96.          

Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain., Zhao L, Saitsu H, Sun X, Shiota K, Ishibashi M., Mech Dev. January 1, 2010; 127 (1-2): 62-72.                

MID1 and MID2 are required for Xenopus neural tube closure through the regulation of microtubule organization., Suzuki M, Hara Y, Takagi C, Yamamoto TS, Ueno N., Development. July 1, 2010; 137 (14): 2329-39.                                                      

MIM regulates vertebrate neural tube closure., Liu W, Komiya Y, Mezzacappa C, Khadka DK, Runnels L, Habas R., Development. May 1, 2011; 138 (10): 2035-47.                            

The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo., Min TH, Kriebel M, Hou S, Pera EM., Dev Biol. October 1, 2011; 358 (1): 262-76.                            

The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1., Jin Z, Mei W, Strack S, Jia J, Yang J., J Biol Chem. October 21, 2011; 286 (42): 36171-9.

Thyroid hormone-induced sonic hedgehog signal up-regulates its own pathway in a paracrine manner in the Xenopus laevis intestine during metamorphosis., Hasebe T, Kajita M, Fu L, Shi YB, Ishizuya-Oka A., Dev Dyn. February 1, 2012; 241 (2): 403-14.        

Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation., Borday C, Cabochette P, Parain K, Mazurier N, Janssens S, Tran HT, Sekkali B, Bronchain O, Vleminckx K, Vleminckx K, Locker M, Perron M., Development. October 1, 2012; 139 (19): 3499-509.                    

Resting potential, oncogene-induced tumorigenesis, and metastasis: the bioelectric basis of cancer in vivo., Lobikin M, Chernet B, Lobo D, Levin M., Phys Biol. December 1, 2012; 9 (6): 065002.

Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model., Chernet BT, Levin M., Dis Model Mech. May 1, 2013; 6 (3): 595-607.                  

The cytoskeletal protein Zyxin inhibits Shh signaling during the CNS patterning in Xenopus laevis through interaction with the transcription factor Gli1., Martynova NY, Ermolina LV, Ermakova GV, Eroshkin FM, Gyoeva FK, Baturina NS, Zaraisky AG., Dev Biol. August 1, 2013; 380 (1): 37-48.                      

Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling., Nedelcu D, Liu J, Xu Y, Xu Y, Jao C, Salic A., Nat Chem Biol. September 1, 2013; 9 (9): 557-64.          

Stabilization of speckle-type POZ protein (Spop) by Daz interacting protein 1 (Dzip1) is essential for Gli turnover and the proper output of Hedgehog signaling., Schwend T, Jin Z, Jiang K, Mitchell BJ, Jia J, Yang J., J Biol Chem. November 8, 2013; 288 (45): 32809-32820.                

Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling., Niewiadomski P, Kong JH, Ahrends R, Ma Y, Humke EW, Khan S, Teruel MN, Novitch BG, Rohatgi R., Cell Rep. January 16, 2014; 6 (1): 168-81.

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